ICON plc

Research Analyst

• Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards
• Conducting site visits to assess site performance, resolve issues, and provide support
• Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting
• Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct
• Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations

Senior Clinical Research Associate

Recruitment

• Launch digital advertising through online channels globally to drive patient recruitment for supported clinical studies with a focus in Google and Meta channels
• Monitor and optimize the performance of digital advertising campaigns and assess performance against goals (ROI and KPIs)
• Produce reports and recommendations concerning current and future advertising and patient recruitment strategies
• Liaise with the marketing team on current and upcoming studies, contributing to the formulation of digital outreach strategies
• Provide strategic input to copywriters drafting patient recruitment advertising materials copy and consult with design and production team members to develop images / video assets
• Liaise with study leads on study start-up requirements and during the study enrollment to deliver against randomization targets
• Liaise with media agencies and external vendors to support patient recruitment initiatives

Patient Recruitment Digital Media Buyer

Clinical Operations

• Manage day-to-day project and program management activities, supporting your team to deliver quality outcomes.
• Developing and executing project plans, focusing on achieving project goals and objectives.
• Leading cross-functional teams to ensure the successful implementation of project activities.
• Collaborating with stakeholders to identify project requirements and define project scope.
• Mentoring and guiding team members, fostering a culture of excellence and continuous improvement.
• Driving the development of project documentation and reports to present findings to stakeholders in a clear and actionable manner.
• Staying abreast of industry trends and emerging technologies to integrate best practices into project management strategies.
• Contributing to organizational growth through effective project leadership and strategic planning.

Regional Clinical Operations Lead

Clinical Research

• Manage and oversee local trial management services throughout the study
• Execution of local milestones from feasibility through study close out
• Resourcing of country-level roles in collaboration and agreement with the study Functional Manager (FM)
• Close collaboration with assigned Local Trial Manager(s), Lead Site Manager, Site Managers, Clinical Trial Associates, and Site Contract Managers
• Inspecting Readiness and AQR at the country level
• Country level ad hoc meetings to address unexpected circumstances that might impact country or study level deliverables
• Provide updates, discuss hurdles, timelines/resources, and potential risks with the study FM
• Assist with necessary documentation for leadership

Clinical Trial Manager

• Manage integration of project team activities, leveraging internal and external resources, expertise and knowledge, along with optimizing CRO resources, expertise and knowledge
• Provide input on trial level operational strategies for clinical trials from protocol design to the final clinical study report for specified studies
• Provide input into global subject/patient recruitment plans
• Relationship management between study sites and vendors
• Manage aspects of CRO/vendor identification and the day to day operational management activities of CROs & other vendors including set up, statement of work creation and budget oversight
• Manage strategic study operations including: study sites and tracking systems for regulatory submissions, drug supply and use, enrollment of subjects, regulatory document flow, study timelines, all budgetary and financial information, performance metrics, data flow, etc
• Create and update critical trial-specific documents (for example country specific ICF) and plans
• Support development of compound and protocol level training materials
• Review and provide input into budgets, timelines, and forecasts for assigned clinical studies
• Interface with internal key stakeholders including, but not limited to; Finance, Program Management, Vendor Management, Safety, Accounting, Clinical Supply, Quality Assurance, Data Management, Statistics, Clinical Research, Commercial, Regulatory, Bio Analytical, Medical Affairs; which may include acting as a liaison between groups
• Provide support for inspection readiness activities and on identification of risks and mitigation plans at the trial level
• Participate in process improvement activities at a trial and department level as needed

Manager, Clinical Operations

Manager

• Manage day-to-day biostatistics activities, supporting your team to deliver quality outcomes.
• Leading a team of statistical analysts and programmers to design and conduct statistical analyses for peri/post approval studies.
• Collaborating closely with cross-functional teams to develop statistical analysis plans and interpret study results.
• Providing statistical expertise and guidance on study design, protocol development, and data interpretation.
• Overseeing the development and validation of statistical models and methodologies for analyzing clinical trial data.
• Contributing to the strategic planning and implementation of statistical analysis projects to support business objectives.

Senior Statistical Manager – RWE, Peri/Post Approval

Director

• Provide scientific expertise and guidance to the Commercial Development and Operations teams within IMC.
• Serve as a scientific expert and point of contact for customers, offering insight and support as needed.
• Review and provide scientific input on imaging charters, site-facing materials, and sponsor-facing reports.
• Ensure projects are designed and implemented appropriately to meet all required imaging endpoints.
• Represent the organization at scientific conventions by delivering presentations, participating in panels, and contributing to imaging standardization initiatives.
• Collaborate with the Marketing division to highlight key differentiators in imaging services for metabolic diseases.
• Conduct sales presentations and maintain strong client relationships, supporting the RFP and RFI processes.
• Act as an internal consultant, offering technical and scientific training and support to team members.
• Contribute to defining requirements for the development of proprietary imaging software for metabolic diseases.
• Travel up to approximately 10%, both domestically and internationally.
• Perform other duties and responsibilities as assigned.

Director, Medical & Scientific Affairs – Imaging

Product Adoption Specialist

• Work with GDO, R&D and cross-functional stakeholders to collect develop and deploy effective support materials for systems in DSDS ownership
• Work with the Business System Owner (BSO) for the system portfolio to identify and understand the system capabilities to create easy to understand user facing materials
• Support clinical systems BSO and change management functions by contributing to process development, training, and change management.
• Develop user facing materials for the system(s) in alignment with GDO/R&D business and strategic priorities
• Support the Business System Owner in the development of the overall clinical system user adoption from material development, change management, and communications
• Partner with the Product Manager(s) for the clinical systems to ensure understanding of forthcoming system capabilities
• Collaborate with system owners and stakeholders to resolve issues promptly and accurately.
• Actively represent the end user’s experience to the BSO to inform any system challenges preventing successful adoption
• Responsible to supporting the education and awareness of available support resources for the end users

Business System Adoption Specialist

• Provide scientific expertise and guidance to the Commercial Development and Operations teams within IMC
• Serve as a scientific expert and point of contact for customers, offering insight and support as needed
• Review and provide scientific input on imaging charters, site-facing materials, and sponsor-facing reports
• Ensure projects are designed and implemented appropriately to meet all required imaging endpoints
• Represent the organization at scientific conventions by delivering presentations, participating in panels, and contributing to imaging standardization initiatives
• Collaborate with the Marketing division to highlight key differentiators in imaging services for metabolic diseases
• Conduct sales presentations and maintain strong client relationships, supporting the RFP and RFI processes
• Act as an internal consultant, offering technical and scientific training and support to team members
• Contribute to defining requirements for the development of proprietary imaging software for metabolic diseases
• Travel up to approximately 10%, both domestically and internationally
• Perform other duties and responsibilities as assigned

• As an intern, you will have the opportunity to rotate through various roles to gain experience in Clinical Delivery.
• Performs all tasks in accordance with applicable guidelines, (e.g., ICH-GCP), company and sponsor SOPs, project plan, study-specific processes, local regulatory requirements.
• Completes essential document collection and review throughout the study lifecycle, organizes and maintains site clinical trial master file (TMF) documents, and maintains site-related data in applicable clinical systems according to procedures and guidelines.
• Ensures timely and complete data entry into CTMS.
• Performs risk assessment and management responsibilities throughout the project including site process evaluation, addressing follow up items and issue escalation.
• Manage additional clinical operations tasks as required and outlined in study job task list.
• Facilitate ordering and tracking of trial materials as needed.
• Assist project teams with trial progress tracking by updating the Clinical Trial Management systems, providing access to study/client systems (as appropriate).

Excel Intern – Clinical Operations

• Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout
• Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements
• Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas
• Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives
• Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites, including for example, novel site models, community-based research initiatives etc
• Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct
• Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery
• Leverage performance metrics to anticipate issues, intervene decisively, and maintain momentum toward clinical milestones
• Drive inspection readiness as a continuous discipline across sites
• Collaborate across functions and with vendor partners to resolve operational barriers, ensuring delivery with speed and quality
• Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization
• Provide oversight and quality assurance for vendor monitoring, escalating risks proactively
• Cultivate a portfolio of strategically aligned, high-impact investigators

Clinical Trial Liaison – Clinical Research Lead

• Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout
• Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements
• Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas
• Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives
• Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites, including for example, novel site models, community-based research initiatives etc
• Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct
• Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery
• Leverage performance metrics to anticipate issues, intervene decisively, and maintain momentum toward clinical milestones
• Drive inspection readiness as a continuous discipline across sites
• Collaborate across functions and with vendor partners to resolve operational barriers, ensuring delivery with speed and quality
• Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization
• Provide oversight and quality assurance for vendor monitoring, escalating risks proactively
• Cultivate a portfolio of strategically aligned, high-impact investigators who consistently prioritize client trials
• Enable an exceptional investigator experience by being a responsive, knowledgeable, and valued scientific partner
• Collaborate cross-functionally (e.g., Medical, Clinical, Study Delivery) to align on trial and site priorities, troubleshooting challenges with urgency and creativity
• Conduct data-informed site prospecting and prioritization, contributing to trial competitiveness and regional strategic execution
• Maintain scientific fluency and therapeutic expertise to lead meaningful, solutions-focused discussions with site personnel
• Act as a key liaison between field teams, vendors, and investigators, ensuring alignment, shared purpose, and continuous knowledge transfer
• Partner closely with field team colleagues to elevate the investigator and site experience, ensuring seamless collaboration and improving enrollment outcomes and Investigator relationships

• Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout
• Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements
• Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas
• Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives
• Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites
• Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct
• Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery
• Collaborate across functions and with vendor partners to resolve operational barriers
• Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization

Compliance

• Manage quality assurance and compliance activities across your area, ensuring your team delivers to the highest standards
• Develop and implement quality assurance strategies and processes to support clinical trial activities
• Conduct comprehensive quality assessments and audits to ensure compliance with regulatory standards and guidelines
• Collaborate with cross-functional teams to identify and address quality issues and implement corrective actions as needed
• Participate in the review and approval of clinical trial documentation and data to ensure accuracy and completeness
• Provide leadership and mentorship to quality assurance staff, fostering a culture of excellence and continuous improvement

Senior Manager, Clinical Compliance

Operations

• Responsible for management/oversight of study and regional/country level activities from study startup through conduct and study close
• May manage the study start up process in countries assigned (where SUPM not assigned) and/or oversee pCRO responsible for these activities as applicable
• Through the Site Care Partner/Country Trial Manager or pCRO supports the Country/investigator outreach process, site identification and feasibility ensuring countries/sites can meet all study protocol requirements
• Provides country level input on Startup and Recruitment milestones as provided by pCRO and/or Country Trial Manager/Site Care Partner to Global Study Manager during planning
• Is accountable for overseeing pCRO and/or Country Trial Manager/Site Care Partner for assigned studies at country level in accordance with the overall project plan, manages and maintains accurate country level plans (e.g. timelines, budget, risk and quality plans)
• Collaborates with accountable roles to identify and manage deviations and risks in study startup and execution and implements mitigation strategies as required
• Is also accountable for resolution of Site Activation escalations to Study Teams including offering options for mitigation
• Leader of the Local Study Team (core members: (Lead) Site Care Partners Clinical Trial Assistant, ad hoc members: ICL, Site Activation Partner, CTRO and Local Regulatory, Medical Affairs colleagues and other key stakeholders as required)
• Ensures compliance to relevant Global and Local, internal and external requirements and regulations
• Ensures timely communication bidirectionally between the global and local study team
• Provides protocol level guidance and support to responsible Local Study Team members as applicable
• Liaise with Site Care Partner, Lead Site Care Partner, Site Activation Partners and Regulatory colleagues in country to agree on submission strategy to Health Authorities and Ethic Committees
• Utilize roles in countries such as Lead Site Care Partner, and expert roles such as Contracts Leads, Site Activation Partners to provide the Global Teams with local intelligence and operational nuances to be considered
• Acts as the study level point of contact for all study-level questions for the Local Study Team, ensuring resolution at lowest possible level, and when needed liaising with and escalating to appropriate global roles/teams
• Follows up on region/country level issue status to ensure resolution
• Identifies country level trends to improve deliverables processes as needed
• Utilizes country intelligence to provide input on country specific risks into preparation of Investigational Quality Management Plan, Study Monitoring Plans, ensures PTMF completeness and oversight of all relevant compliance activities for allocated studies
• Ensures audit/Inspection readiness during start-up and conduct
• Manages applicable Quality Events with pCRO and local team as applicable and required
• Coordinates effective site recruitment planning to allow for implementation of plans at the country and site level, consistent with global plan and local targets
• Responsible to drive and ensure delivery of data cleaning deliverables for pCRO and sites as applicable
• Provides input on Country level Per Subject Costs, local vendor costs and other fees where applicable
• May act as a Subject Matter Expert
• May lead operational effectiveness initiatives at country or regional level
• Responsible for PTA and SIV report review for reports completed by the Site Care Partner
• Supports implementation of client’s Site Technology Experience systems (e.g. Shared Investigator Platform SIP, Centralized Account Management CAM)
• Support to EC/RA and other relevant (e.g. radiation, biobank) submissions and deficiency/query responses for initial and subsequent CTA submissions within required timelines
• Drives pCRO and/or applicable internal study team members to ensure PTMF set up meets study requirements, and maintains oversight of PTMF completeness
• Provides country level documents to PTMF and maintains oversight of Investigator Site File (ISF) reconciliation and completeness actions
• Ensure pCRO and/or applicable internal study team members maintain appropriate level IP/equipment/ancillary supplies management including Import/Export License management with the support of Clinical Trial Assistants and other roles as required
• Supports implementation of new tools and technologies (e.g. eConsent, eISF, Remote Source Access, remote SDV/SDR, iConnect, implementation of protocol required decentralized trial options etc.)
• Support Identification, contract development and management of local vendors or facilities as per protocol
• Investigator Meeting support and management including doing presentations as appropriate
• Management of local Investigator Meetings including doing presentations as appropriate

Senior Clinical Research Associate

Patient Recruitment Digital Media Buyer

Regional Clinical Operations Lead

Clinical Trial Manager

Manager, Clinical Operations

Senior Statistical Manager – RWE, Peri/Post Approval

Director, Medical & Scientific Affairs – Imaging

Business System Adoption Specialist

Director, Medical & Scientific Affairs – Imaging

Excel Intern – Clinical Operations

Clinical Trial Liaison – Clinical Research Lead

Clinical Trial Liaison – Clinical Research Lead

Clinical Trial Liaison – Clinical Research Lead

Senior Manager, Clinical Compliance

Country Study Operations Manager