Praxis

Program Manager

• Operationalize the HUB: Stand-up core PSP operations including intake pathways, process flows, SOPs, training materials, call guides, FAQs, and quality controls
• Support Salesforce CRM build and systems integrations: Partner with vendor partners and technology teams to support CRM configuration, data flows, and end-to-end systems integrations; ensure tools are connected, functional, and aligned to HUB workflows; willing to explore and implement AI-powered features, automation capabilities, and emerging integrations to drive operational efficiency and unlock new ways of working
• Build, manage and lead day-to-day operations: Recruit, onboard, develop and performance manage a high-performing patient support team, establishing clear roles, accountability structures, and a culture of excellence ahead of launch
• Establish and manage performance standards: Define SLAs, monitor performance, conduct root-cause analysis, and hold teams and vendors accountable
• Partnership & Collaboration: Ensure clear, consistent handoffs across HUB, field teams, MSLs, market access, and vendor partners; serve as the primary operational liaison across commercial, medical, legal, and market access functions, influencing without authority to drive alignment
• Own the patient and HCP experience: Take end-to-end ownership of the patient and HCP journey, ensuring every touchpoint is seamless, compliant, and centered on access and support outcomes
• Manage escalations: Own complex case escalations, patient safety events, and adverse event reporting pathways, ensuring timely resolution and appropriate documentation
• Vendor oversight and management: Formally manage vendor performance, contract adherence, and relationships; where applicable, lead or support HUB vendor evaluation and onboarding
• Embed compliance into execution: Ensure HIPAA adherence, audit readiness, and appropriate controls across all workflows in partnership with Legal and Compliance
• Drive data integrity and visibility: Define reporting needs and ensure accurate case documentation and data capture to enable visibility into performance, access barriers, and risk
• Stakeholder reporting: Provide regular updates to senior leadership on program performance, KPIs, risks, and operational health
• Own budget and resources: Manage operational budget, vendor contracts, and cost tracking to ensure fiscal accountability and resource alignment
• Own launch readiness: Identify operational gaps early, prioritize fixes, and ensure the program is fully functional and resilient for launch, recognizing this is a full build with a 3-month runway
• Translate strategy into execution: Implement program design, pressure-test workflows, and ensure processes perform reliably in real-world conditions on day one

Director, Patient Support Program Operations

Product Manager

• Lead development and execution of integrated product and commercialization strategies aligned to corporate and portfolio objectives
• Drive cross-functional alignment across Commercial, Medical Affairs, Market Access, Regulatory, Clinical, and Corporate Communications teams to support launch readiness and ongoing product strategy
• Translate scientific and clinical data into differentiated product positioning, messaging, and customer engagement strategies
• Partner with market research and analytics teams to generate actionable insights from customer feedback, market dynamics, competitive intelligence, and performance metrics
• Lead development of disease education, promotional, and non-promotional initiatives in partnership with agency and internal stakeholders
• Identify strategic risks, gaps, and opportunities proactively, helping teams make informed business tradeoff decisions
• Manage complex initiatives across multiple stakeholders while ensuring speed, quality, accountability, and compliance
• Contribute to long-range planning, portfolio strategy discussions, and commercialization readiness activities
• Serve as a collaborative leader and trusted thought partner who elevates cross-functional execution and organizational effectiveness

Senior Marketing Product Manager

Analytics Engineer

• Design, develop, and maintain scalable ETL/ELT pipelines that support cross-functional data needs
• Build, deploy, and optimize analytical dashboards and other reporting tools to support strategic decision-making
• Write well-structured, testable code in Python, R, and SQL to support analytics workflows
• Lead the development and best practices of version control, documentation, and coding standards
• Partner with data scientists to bring analytics products from prototype to production
• Identify and integrate AI-driven tools to enhance data processing and reporting capabilities
• Mentor junior team members and contribute to a culture of knowledge sharing and continuous improvement

Data and Analytics Engineer III

Payroll

• Own end-to-end U.S. multi-state payroll processing, ensuring accuracy, timeliness, and full regulatory compliance
• Administer equity programs including stock options, RSUs, and ESPP across the full lifecycle
• Partner with Fidelity or similar platforms to manage equity operations and maintain data integrity
• Design and maintain SOX-compliant payroll and equity controls, including documentation, reconciliations, and audit support
• Build and continuously strengthen audit-ready infrastructure that scales with company growth
• Improve payroll and equity workflows to increase efficiency while maintaining strong controls
• Ensure compliance with federal, state, and local payroll tax regulations, filings, and reporting
• Maintain and reconcile data across payroll, equity, HRIS, and finance systems
• Serve as a trusted resource for employees, resolving payroll and equity questions clearly and quickly
• Partner with Finance, People, Legal, and external auditors to ensure alignment and audit readiness

Manager, Payroll – Stock Administration

Manager

• Serve as the reimbursement and access lead for the assigned territory.
• Partner with provider offices, hospitals, specialty pharmacies, and internal teams.
• Educate healthcare providers and office staff on payer coverage requirements.
• Proactively manage complex patient access scenarios.
• Build trusted relationships with neurologists and institutional stakeholders.
• Serve as a strategic field partner to Market Access and Commercial leadership.
• Maintain compliant and accurate documentation of field activities.

Field Reimbursement Manager

Director

• Execute trade and distribution strategies across rare disease and broader market channel models.
• Lead implementation and oversight of 3PL partners, including inventory flow, order-to-cash, reverse logistics, and SLA management.
• Support selection, onboarding, and operational management of specialty pharmacy partners.
• Drive implementation of data aggregation capabilities across 3PLs, specialty pharmacies, and digital pharmacy partners.
• Ensure serialization readiness, DSCSA compliance, and audit preparedness across products.
• Serve as the primary operational lead across external trade, distribution, and data partners.
• Partner cross-functionally with Market Access, Finance, Patient Services, and IT to ensure aligned execution and launch readiness.

Senior Director of Trade and Distribution

Chief Marketing Officer

• Support and strengthen brand strategy
• Partner closely with the Brand Lead to translate strategy into action
• Deliver exceptional execution across HCP and patient initiatives
• Analyze campaign performance and market dynamics
• Lead execution of patient-focused initiatives

Associate Director – Marketing

Research Scientist

• Serve as Analytical Lead across CMC programs, with primary responsibility for oligonucleotide analytical development activities and support for small molecule programs.
• Lead analytical method development, qualification, validation, transfer, and GMP testing activities across internal teams and external partners.
• Drive technical troubleshooting, data interpretation, method lifecycle management, and review of analytical documentation including validation reports, stability reports, specifications, and CoAs.
• Design and implement phase-appropriate analytical control strategies, specifications, and stability programs for oligonucleotide and small molecule drug substances and drug products.
• Direct and manage CRO/CMO analytical partners to ensure high-quality execution, strong communication, and continuous operational improvement.
• Collaborate cross-functionally to strengthen CMC operations, improve processes, and establish scalable technical and business practices across the analytical function.
• Contribute strategic and technical expertise to support regulatory filings, commercialization readiness, and ongoing product lifecycle management.

Principal Scientist, Analytical Development, Oligo and Small Molecule

Sales

• Lead, coach, and develop a team of field sales professionals to achieve and exceed commercial objectives.
• Drive execution of a unified commercial strategy across the region in alignment with enterprise priorities.
• Partner with Commercial, Medical Affairs, Patient Services, and Market Access to deliver coordinated customer engagement.
• Support field readiness and execution across pre-launch, launch, and post-launch phases.
• Ensure teams are equipped with the capabilities, tools, and behaviors required for successful product launches.
• Drive performance through clear goal setting, KPI tracking, and ongoing coaching.
• Provide insights from the field to inform strategy and improve execution.
• Build a strong, accountable, and high-performance team culture.
• Ensure compliance with all regulatory and company policies.

Regional Sales Director

• Lead and develop a team of Field Reimbursement Managers (FRMs), setting clear performance expectations aligned to patient impact and business priorities
• Define and execute the national field reimbursement strategy, ensuring consistent, high-quality support across territories
• Drive accountability through clear metrics (time to therapy initiation, PA approval rates, appeal success, patient onboarding progression, etc.)
• Partner cross-functionally with Market Access, Patient Services, Commercial, Compliance, and Specialty Pharmacy partners to proactively address systemic access barriers
• Analyze field trends across payers, regions, and provider types; escalate patterns and recommend strategic interventions to leadership
• Build strong external relationships with key neurology practices, specialty pharmacies, and access stakeholders to strengthen Praxis’ reputation as a credible access partner
• Recruit, coach, and retain top-tier reimbursement talent aligned with Praxis values of Trust, Ownership, Curiosity, and Results

Director, Field Reimbursement

• Manage, lead and develop a team of field-based Clinical Educators.
• Ensure patients experience seamless onboarding and clear education.
• Partner cross-functionally with Patient Services, Market Access, Medical, Commercial, and Specialty Pharmacy partners.
• Monitor field trends, patient feedback, and operational challenges.
• Maintain high standards of compliance and adherence to company policies.

Director, Clinical Educator Team

• Lead and develop regional sales and account management teams to deliver strong performance and achieve commercial objectives.
• Drive execution of a unified commercial strategy across geographies in alignment with enterprise priorities.
• Oversee strategic account engagement, including health systems, IDNs, IPNs, and key payer relationships.
• Partner closely with Commercial, Medical Affairs, Patient Services, and Market Access to deliver coordinated customer engagement.
• Drive field readiness and execution across pre-launch, launch, and post-launch phases for multiple products.
• Ensure sales teams are equipped with the capabilities, tools, and behaviors required for successful product launches.
• Build scalable processes, infrastructure, and performance management systems to support growth.
• Establish clear metrics to measure effectiveness and drive continuous improvement across the field.
• Recruit, develop, and retain top talent while building a high-performance, accountable culture.
• Provide insights from the field to inform strategy, execution, and future capability development.

Area Vice President, Sales

IT Support

• Serve as the go-to escalation point for Level 2 IT issues from our internal Helpdesk
• Troubleshoot and resolve complex problems across Microsoft 365, collaboration tools, and endpoint devices
• Support onboarding and offboarding workflows for employees, consultants, and contractors
• Administer user access and authentication across Microsoft Entra ID and SaaS platforms
• Manage SSO, MFA, password managers (1Password), certificates, and guest access
• Handle admin consent requests and configure access for contractors and temporary roles
• Administer permissions for SharePoint, DocuSign, Zoom AI, Atlassian, and other SaaS tools
• Conduct periodic license reviews and audits across enterprise applications
• Oversee laptop shipping, imaging, and inventory tracking in Jira
• Manage conference room AV systems and recordings for company-wide meetings as needed to support vendors
• Respond to security-related alerts and support access to secure systems and VPNs
• Partner with vendors and internal teams to manage OEM support and renewals
• Maintain IT knowledge base in Confluence and refine workflows
• Proactively identify and implement improvements to enhance support quality and user experience

IT Support Specialist, Tier II

• Serve as the first line of support for user technical issues across hardware, software, and collaboration tools.
• Troubleshoot and resolve problems involving Microsoft 365 Business applications, including Outlook, Teams, SharePoint, and OneDrive.
• Assist with basic configuration, user provisioning, and license management in Microsoft Entra, Defender, and SharePoint environments.
• Maintain and update IT documentation including procedures, system configurations, and knowledge base articles.
• Provide user support and training for productivity and collaboration tools such as Adobe Acrobat, Jira, Confluence, Zoom, and Microsoft Teams.
• Coordinate with vendors and third-party support as necessary to resolve technical issues.
• Monitor IT support queues, escalate complex incidents appropriately, and follow up to ensure resolution.
• Assist in onboarding and offboarding activities including account setup, access permissions, and hardware provisioning.
• Contribute to continuous improvement of IT service processes and user experience.

IT Support Specialist, Tier I

People Operations

• Partner with Commercial leadership to shape organizational design and talent strategy for business goals.
• Coach leaders with actionable feedback on performance and accountability.
• Drive talent decisions (hiring, promotions, exits) with high standards.
• Operate across the employee lifecycle from recruiting to performance management.
• Lead performance and feedback processes ensuring accountability.
• Diagnose and implement solutions for organizational friction.
• Engage with frontline teams to evolve leadership or structure as necessary.
• Build operating rhythms (OKRs, talent reviews) to improve execution.