Praxis

Analytics Engineer

• Design, develop, and maintain scalable ETL/ELT pipelines that support cross-functional data needs
• Build, deploy, and optimize Power BI dashboards and other reporting tools to support strategic decision-making
• Write well-structured, testable code in Python, R, and SQL to support analytics workflows
• Lead the development and enforcement of version control, documentation, and coding standards
• Partner with data scientists to bring analytics products from prototype to production
• Identify and integrate AI-driven tools to enhance data processing and reporting capabilities
• Mentor junior team members and contribute to a culture of knowledge sharing and continuous improvement

Data & Analytics Engineer II

Engineer

• Own and manage the configuration, deployment, and optimization of Microsoft Intune across all corporate devices
• Own and understand dynamic software patching and deployment of patching using modern tools
• Administer and troubleshoot Microsoft Entra (Azure AD) to support secure access and identity management
• Develop and enforce device compliance policies, ensuring security standards are met across endpoints
• Partner with IT leadership to refine endpoint strategy and tooling as we scale
• Proactively monitor, detect, and remediate issues impacting device health, performance, or security
• Build and maintain documentation, SOPs, and automated workflows for efficiency and consistency
• Serve as a go-to resource for device-related escalations and user support

Intune Engineer

Compliance

• Design, implement, and scale Praxis’s commercial compliance program in advance of first launch, including policies, SOPs, governance, risk assessment, monitoring and training.
• Establish launch-ready corporate compliance controls supporting commercial operations.
• Serve as a standing MLR member, providing regulatory, legal, and compliance review of promotional materials.
• Ensure alignment with FDA regulations, OPDP guidance, and company standards.
• Partner with Commercial and Medical teams to enable efficient, compliant review and messaging.
• Define MLR processes, timelines, precedents, and escalation pathways.
• Train internal stakeholders on promotional compliance, scientific exchange, and appropriate data use.
• Advise on compliant use of clinical, safety, and real-world data across promotional and non-promotional channels.
• Conduct launch-focused compliance risk assessments and implement monitoring activities.
• Support investigation and remediation of commercial compliance issues in partnership with Legal and HR.

Director, Commercial Compliance

• Serve as Praxis’s lead point of contact with our Contract Manufacturing Organizations (CMOs).
• Work onsite at partner facilities to validate small molecule API manufacturing processes.
• Ensure successful tech transfer and support commercial readiness.
• Oversee future production to maintain reliable supply.
• Understand written chemical synthesis processes and translate those to instructions for industrialized execution.
• Efficiently gather, analyze, and archive data to support regulatory filings.
• Review documentation from CMOs and lab partners including instructions, procedures, and batch records.
• Work alongside Quality Assurance to ensure follow of regulations and standards in all processes executed by third parties.
• Adhere to industry guidelines and standards including cGMPs.
• Travel required - PIP at CMOs (US and worldwide).

Senior Manager – Process Engineer, Drug Substance

Director

• Collaborate with key stakeholders to execute a comprehensive investor relations strategy aligned with corporate objectives and long-term value creation.
• Articulate a clear and compelling investment thesis that integrates scientific rationale, clinical data, regulatory strategy, and financial outlook.
• Lead preparation of earnings materials, investor presentations, fact sheets, Q&A documents, and corporate messaging.
• Keep track of investor interactions, organize meetings, and coordinate presence at investor conferences including developing a strategy for identifying and meeting a target list of investors.
• Oversee investor-facing sections of press releases, SEC filings, and the corporate website for consistency and accuracy.
• Serve as a primary point of contact for institutional investors, analysts, and proxy advisory firms.
• Manage earnings calls, investor days, conference participation, non-deal roadshows, and one-on-one investor meetings.
• Build and maintain strong relationships with sell-side analysts to ensure accurate coverage.
• Partner with Finance, Legal, and external advisors to ensure compliance with SEC regulations and Reg FD requirements.
• Monitor peer activity, valuation trends, sell-side price targets & valuation models, and industry developments within the biotech and life sciences sector.
• Approximately 25% travel, including investor conferences, roadshows, and meetings.

Director, Investor Relations

Supply Chain

• Ensure clinical trials are ready to run without delay, disruption, or waste.
• Responsible for the end-to-end planning, execution, and oversight of clinical supply activities.
• Manage supply strategy development, forecasting, and demand planning.
• Handle depot and site supply management, returns, reconciliation, and destruction.
• Develop and maintain integrated supply plans aligned with protocol requirements.
• Support study startup activities and monitor supply performance.
• Manage relationships with clinical supply vendors and lead forecasting discussions.
• Author, review, and approve clinical supply-related documents to ensure compliance.

Manager, Clinical Supply Chain

Manager

• Manage day-to-day ticket intake performance and ensure SLAs are met or exceeded.
• Serve as the primary point of escalation for Tier I tickets, resolving issues or coordinating handoff to Tier II as needed.
• Support the Tier II team on ongoing IT maintenance and infrastructure projects.
• Identify and escalate trends in hardware and licensing needs before they impact the business.
• Coach, mentor, and develop a small team (3–4) of Tier I Service Desk Specialists.
• Partner cross-functionally with internal teams and external vendors to ensure seamless service.
• Develop documentation, workflows, and training to improve consistency and efficiency.

Service Desk Manager

Research Analyst

• Support study execution by managing meeting logistics, documenting decisions, and tracking action items.
• Partner with Clinical Operations and site monitors to ensure protocol compliance and quality standards are met.
• Responsible for filing the site-level documents into the Trial Master Files (TMFs) in a timely manner.
• Track, review, and organize essential documents from sites and vendors.
• Identify, escalate, and help resolve site-level issues in collaboration with cross-functional teams.
• Assist with regulatory submissions and other study deliverables.
• Drive process improvements that enhance speed, quality, and patient impact.

In-House Clinical Research Associate, CRA

Financial Planning and Analysis

• Act as the primary FP&A partner to Commercial leadership, supporting brand strategy, launch planning and revenue forecasting from pre-launch through scale.
• Perform revenue modeling, scenario and sensitivity analyses and key commercial assumptions as the business grows to multi-billion-dollar revenue levels.
• Partner closely with CMC and Supply Chain teams on inventory assumptions, demand planning and working capital considerations.
• Collaborate cross-functionally on pricing, gross-to-net, market access and demand dynamics.
• Lead Commercial and CMC input into budgets, ongoing forecasts and long-range plans.
• Evaluate investment decisions through ROI analysis and financial modeling to support prioritization and resource allocation.
• Develop executive-ready materials that clearly communicate risks, opportunities and trade-offs.
• Continuously improves forecasting tools, processes and analytical rigor to support a scaling commercial organization.

Director, Commercial FP&A

Accountant

• Support the monthly general ledger close process, including preparation and review of journal entries, reconciliations and supporting schedules.
• Assist in preparation of commercial related accruals and R&D accruals, including coordination with functional stakeholders and timely recording in the general ledger.
• Perform cash reconciliations as part of the monthly close process and investigate and resolve variances.
• Assist with the preparation of monthly, quarterly and annual financial reporting deliverables.
• Support budgeting and forecasting activities in collaboration with the FP&A team, including data gathering, analysis and tracking of actuals versus forecast.
• Maintain and improve accounting processes, documentation and controls to support accuracy and scalability.
• Collaborate cross-functionally to ensure timely, accurate financial information and support ad hoc analyses as needed.

Senior Accountant

• Own the design and execution of revenue and inventory accounting processes, including revenue recognition, gross-to-net deductions, inventory valuation, reserves, and GL close activities, in compliance with U.S. GAAP (ASC 606) and SOX requirements.
• Establish and maintain accounting processes related to government pricing programs, including Medicaid, Medicare and other federal and state programs.
• Partner closely with cross functional stakeholders and external auditors to support accounting policy development, documentation, audit readiness, and ongoing compliance.
• Design and operationalize gross-to-net processes, including controls, reconciliations and data flows with third-party vendors.
• Build and maintain inventory accounting and operational processes in partnership with supply chain and 3PL providers.
• Lead the implementation and optimization of systems and tools supporting revenue, inventory, and government pricing processes.
• Serve as the primary Finance partner for revenue, inventory and government pricing operations.

Director, Revenue and Inventory

• Providing oversight and daily management of all activities pertaining to drug safety within the Praxis pharmacovigilance (PV) department globally.
• Leadership and oversight of global PV operations, personnel and strategic resource planning.
• Oversight of developing compliant PV procedures and training modules.
• Oversight of timely safety reporting to regulatory authorities and external business partners.
• Implementation of strategies to manage safety risks.
• Ensure the PV department maintains inspection readiness, including representing the company during audits and pharmacovigilance inspections.
• Monitor key performance indicators for PV vendors.
• Collaborate cross-functionally to ensure timely authoring of key safety deliverables including periodic safety updates and regulatory query responses.
• Lead PV/safety aspects of NDA/MAA preparation, including authoring of integrated safety summary and drafting labeling.
• Leads capabilities enhancement within PV, including implementation of safety database and data visualization tools for signal detection.
• Oversight of relationships with external business partners, including overseeing the alliance, associated requests, and PV agreements, ensuring mechanisms are in place for governance of partnerships.

Senior Director, Safety/Pharmacovigilance

Research Scientist

• Responsible for translating the processes and products for Praxis’ clinical and commercial pipeline from the laboratory to the manufacturing environment.
• Use knowledge of analytical method development, qualification, validation, and troubleshooting to deliver to Analytical Team.
• Strong collaboration with Drug Substance/Drug Product scientists, engineers, Quality and manufacturing to ensure efficiency and control.
• Lead contributing to ensuring the analytical function is agile and at the forefront in the industry.
• Deliver to product teams within CMC to realize Praxis’ pipeline of innovative medicines for neurological disease.
• Involved in all analytical deliverables with CMC program while acting as Analytical lead, including management and execution of analytical testing.

Principal Scientist, Analytical Development

• Involved in supporting analytical deliverables of the CMC programs while working in conjunction with CMC team members.
• Management of analytical testing in our external network, especially as it relates to GMP drug substances and drug products.
• Ensuring that analytical documentation (protocols, reports, methods, COAs, change controls, etc.) are added contemporaneously to Praxis’ document management system.
• Oversight and coordination of CMC stability and reference standard programs.
• Direct monitoring of our external network providers that execute Analytical Development activities to ensure deliverables and continuously improve efficiency.
• Supporting the design and development of phase-appropriate quality control strategies, specifications, and stability studies for drug substance and drug product.
• Contribute to the overall CMC team in terms of execution.
• Collaborate with other functions of Praxis CMC to establish the technical and business practices of the team.

Data & Analytics Engineer II

Intune Engineer

Director, Commercial Compliance

Senior Manager – Process Engineer, Drug Substance

Director, Investor Relations

Manager, Clinical Supply Chain

Service Desk Manager

In-House Clinical Research Associate, CRA

Intune Engineer

Director, Commercial FP&A

Senior Accountant

Director, Revenue and Inventory

Senior Director, Safety/Pharmacovigilance

Principal Scientist, Analytical Development

Senior Manager, Analytical Development