Director, Patient Support Program Operations

Praxis

Director of Patient Support Program Operations overseeing HUB operations at Praxis Precision Medicines. Focused on launching patient support programs in the rare disease space.

Posted 6/4/2026full-timeRemote • 🇺🇸 United StatesLead💰 $215,000 - $235,000 per yearWebsite

About the role

Key responsibilities & impact

Operationalize the HUB: Stand-up core PSP operations including intake pathways, process flows, SOPs, training materials, call guides, FAQs, and quality controls
Support Salesforce CRM build and systems integrations: Partner with vendor partners and technology teams to support CRM configuration, data flows, and end-to-end systems integrations; ensure tools are connected, functional, and aligned to HUB workflows; willing to explore and implement AI-powered features, automation capabilities, and emerging integrations to drive operational efficiency and unlock new ways of working
Build, manage and lead day-to-day operations: Recruit, onboard, develop and performance manage a high-performing patient support team, establishing clear roles, accountability structures, and a culture of excellence ahead of launch
Establish and manage performance standards: Define SLAs, monitor performance, conduct root-cause analysis, and hold teams and vendors accountable
Partnership & Collaboration: Ensure clear, consistent handoffs across HUB, field teams, MSLs, market access, and vendor partners; serve as the primary operational liaison across commercial, medical, legal, and market access functions, influencing without authority to drive alignment
Own the patient and HCP experience: Take end-to-end ownership of the patient and HCP journey, ensuring every touchpoint is seamless, compliant, and centered on access and support outcomes
Manage escalations: Own complex case escalations, patient safety events, and adverse event reporting pathways, ensuring timely resolution and appropriate documentation
Vendor oversight and management: Formally manage vendor performance, contract adherence, and relationships; where applicable, lead or support HUB vendor evaluation and onboarding
Embed compliance into execution: Ensure HIPAA adherence, audit readiness, and appropriate controls across all workflows in partnership with Legal and Compliance
Drive data integrity and visibility: Define reporting needs and ensure accurate case documentation and data capture to enable visibility into performance, access barriers, and risk
Stakeholder reporting: Provide regular updates to senior leadership on program performance, KPIs, risks, and operational health
Own budget and resources: Manage operational budget, vendor contracts, and cost tracking to ensure fiscal accountability and resource alignment
Own launch readiness: Identify operational gaps early, prioritize fixes, and ensure the program is fully functional and resilient for launch, recognizing this is a full build with a 3-month runway
Translate strategy into execution: Implement program design, pressure-test workflows, and ensure processes perform reliably in real-world conditions on day one

Requirements

What you’ll need

Rare disease experience is required; candidates without direct rare disease PSP or HUB experience will not be considered
Direct experience managing internal HUB operations is required; this is not a role for candidates whose experience is limited to oversight of fully outsourced models
7+ years of progressive experience in patient services, PSP operations, or HUB leadership supporting patients and HCPs within the rare disease environment
Proven experience building or operationalizing PSP infrastructure in pre-launch or early commercial settings; direct experience launching a program from inception, not just managing an existing one
Experience with small patient populations, named patient programs, or rare disease registry requirements strongly preferred
Strong ability to translate strategy into execution with a focus on reliability, scalability, and real-world performance
Demonstrated cross-functional leadership and ability to influence without authority across commercial, medical, legal, and market access teams
Proven change management skills with the ability to build, pivot, and adapt quickly in a fast-moving, pre-launch environment
Hands-on experience configuring or administering a Salesforce CRM platform within a patient services or HUB environment strongly preferred
Demonstrated curiosity and willingness to explore AI-driven tools, workflow automation, and innovative technology integrations — bringing a solutions-oriented, outside-the-box mindset to operational challenges

Benefits

Comp & perks

99% of the premium paid for medical, dental and vision plans
Company-paid life insurance
AD&D
Disability benefits
Voluntary plans to personalize your coverage
401(k) contributions matched dollar-for-dollar up to 6%
Long-term stock incentives
Employee Stock Purchase Plan (ESPP)
Discretionary quarterly bonus
Flexible wellness benefit
Generous PTO
Paid holidays
Company-wide shutdowns

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Salesforce CRM configurationdata integrationroot-cause analysisperformance managementbudget managementprogram designworkflow automationdata capturecompliance adherencepatient support program (PSP) operationalization

Soft Skills

cross-functional leadershipinfluence without authoritychange managementstrategic executionproblem-solvingadaptabilityteam developmentcommunicationcollaborationaccountability