Crinetics Pharmaceuticals

Director

• Develop and implement strategies to protect Crinetics’ intellectual property
• Manage patent prosecution in-house and by outside counsel
• Identify commercially valuable IP in collaboration with teams
• Manage prosecution of high-quality patent applications
• Conduct and manage freedom-to-operate and patentability analyses
• Review and assist in negotiating IP provisions of agreements
• Provide coaching and mentoring to direct reports

Senior Director, Intellectual Property

Financial Planning and Analysis

• Lead and own commercial financial forecasting processes, including revenue, gross‑to‑net, demand planning assumptions, and commercial performance modeling, ensuring alignment across key cross‑functional partners
• Oversee commercial operating expense planning, partnering closely with commercial leadership to ensure financial discipline, optimized resource allocation, and alignment with corporate objectives
• Serve as the primary strategic finance partner to commercial leaders, providing insights and recommendations that support product launch readiness, market planning, and commercial execution strategies
• Analyze and communicate monthly and quarterly commercial performance, identifying trends, risks, and opportunities, and presenting clear recommendations to executive leadership
• Conduct ROI analyses for sales, marketing, and market access initiatives to ensure capital deployment supports commercial effectiveness and product performance
• Drive consistency in forecasting methodologies, assumptions, and reporting across Commercial, Accounting, NPP, and S&OP
• Lead the recurring commercial purchase order review process, enforcing financial controls and ensuring well‑supported and value‑driven investments
• Partner with Commercial, NPP, S&OP, and Accounting to ensure pricing strategies, demand expectations, accruals, and revenue recognition processes are aligned and financially sound
• Support long‑range planning through scenario modeling, sensitivity analysis, and evaluation of commercial strategies
• Promote continuous improvement across commercial FP&A processes to enhance accuracy, efficiency, and collaboration

Associate Director, Commercial FP&A

Content Writer

• Ensure company compliance with clinical trial transparency laws and requirements by applying expert knowledge of key regulatory frameworks, including FDAA 801 and Final Rule and CTR 536/2014
• Work with cross-functional teams to develop content for clinical trial and results postings and post all approved materials in accordance with regulations
• Develop and implement internal procedures, processes, templates, and tools for all aspects of clinical trial disclosure
• Develop and maintains CCI documents (process owner)
• Prepare redacted documents for postings ensuring CCI and personal protected information (PPI) in accordance with the General Data Protection Regulation in the EU and other privacy laws are identified for redaction and redacted from documents that are posted publicly
• Apply logic, attention to detail, critical thinking, good judgement, and follow-up skills to every deliverable and situation
• Approach all engagements with cross-functional team members with a customer-service mindset
• Other duties as assigned

Manager, Trial Disclosure, Medical Writing Operations

Account Manager

• Strategically lead a small team of therapeutic specialists while maintaining strong territory responsibilities
• Consistently share insights and critical field intelligence with the Region Business Director
• Meet or exceed the prescription and revenue targets for each product within assigned territory/account.
• Develop and maintain thorough understanding of the marketing plan for each product.
• Deliver the product messages in an accurate and persuasive manner that is consistent with the marketing plan and results in utilization of Crinetics’ products.
• Develop an understanding of each customer’s (physician & managed care/market access) needs and deliver messages and programs that effectively address them.
• Develop and maintain productive business relationships with customers (physicians, staff, nurses, administrators, etc.) throughout the territory.
• Develop and analyze territory reports to identify opportunities to increase sales of Crinetics’ products.
• Implement plans to address opportunities.
• Manage territory and develop routing that provides for maximum efficiency and attainment of the call plan.
• Continually update knowledge of Crinetics and competitive products to act as a resource to customers.
• Complete administrative duties as required in an accurate and timely manner.
• Stay within expense guidelines.
• Develop and follow a plan of self-development to ensure continual development and attainment of career objectives.
• Communicate routinely and effectively with peers, management & marketing.
• Solid, proven persuasion skills
• Analyze the territory to evaluate opportunities and implement a tactical plan for consistent growth of the business

Strategic Account Manager

Project Manager

• Lead project management efforts associated with commercialization activities to support successful execution across the Palsonify franchise (including multiple indications) and related commercialization initiatives
• Provide PM leadership and operational support to Brand, Commercial, and Evidence Generation Teams (EGT) across Palsonify indications, enabling coordinated planning, readiness, execution, and post-launch optimization
• Organize and facilitate Launch Readiness Team (LRT) and other commercialization workstream meetings, including agendas, attendee management, minutes, decisions, and action items
• Accurately and efficiently maintain and track detailed cross-functional timelines and milestones for all components of launch and commercialization plans (e.g., marketing/brand, commercial operations, sales, market access, patient services, supply/operations, CMC, medical affairs)
• Facilitate identification of key dependencies, risks, and issues; drive risk mitigation strategies, decision support, and contingency planning
• Maintain dashboards and reporting mechanisms for launch status, risks, decisions, and critical path updates for team, senior/executive leadership, and Board-facing forums
• Facilitate communications across departments to gather inputs, align priorities, and share project updates; ensure clarity of owners, deliverables, and deadlines
• Maintain an integrated commercialization calendar identifying critical decision points, governance reviews, team events, and milestones
• Partner with Product/Program Project Management to ensure appropriate integration with Global Product Team strategy, timelines, and reporting (including alignment between commercialization and development activities as needed)
• Support preparation for governance reviews, such as Executive Leadership Team, Product Portfolio Committee, and other executive program presentations
• As the organization evolves, support expansion of scope into broader franchise governance in partnership with Global Product Leadership and Product/Program PM
• Mentor and support project manager(s) assigned to commercialization sub-teams/workstreams; ensure consistency of PM practices and reporting
• Drive creation and continuous improvement of PM tools, templates, and best practices; contribute to PMO initiatives and operating rhythms
• Lead or support additional cross-functional commercialization, PPAM, or enterprise projects from initiation through closeout, including risk/issue management and status reporting
• Focus on immediate and short-term (<2 years) strategic planning horizon while building scalable readiness mechanisms that can extend to future portfolio needs
• Coach and mentor direct reports to develop skills, knowledge, and career growth
• Other duties as assigned

Director, Project Management, Commercialization

Manager

• Manage release testing and stability programs for various projects in commercial, preclinical and clinical development internally or at external parties.
• Author, review, and approve stability protocols; responsible for planning, execution, data management, data analysis, and data trending to support drug substance (API)/drug product retest period/shelf-life determination.
• Manage reference material program.
• Review raw data to support release testing, stability testing, and reference materials qualification.
• Manage, report, and trend stability data.
• Escalate trends and support associated investigations, including temperature excursion assessment, client and regulatory requests.
• Own and support stability-related deviations, investigations, CAPAs, and change controls.
• Work in close collaboration and support with other members of the Technical Operations team responsible for API and DP development and provide support to management as necessary.
• Support regulatory filings (including INDs, IMPDs, NDAs, briefing packages, and other regulatory dossiers), specifically stability and reference material sections.
• Recommend updates and participate in authoring/reviewing of the department related Standard Operating Procedures and guidelines.
• Maintain QC SOPs, methods, specifications, and other associated documents.
• Review analytical methods, technical reports, specifications, corrective/preventative actions, change controls, investigations, and deviations to ensure compliance with cGMP and company standards.
• Support QA on quality system and compliance activities, including audit functions.
• Stay current on industry trends, practices, and regulatory guidelines.
• Present stability updates to various internal audience.

Manager, Quality Control – Stability

• Responsible for driving cross-functional execution and providing strategic operational leadership for Crinetics’ oncology portfolio
• Create and maintain integrated cross-functional development plans aligned with governance expectations
• Lead program operating rhythms and governance forums, proactively anticipate risks and interdependencies
• Provide clear, executive-ready visibility into critical path, decisions, and resourcing implications
• Facilitate identification of key dependencies, risks, and issues
• Maintain dashboards and reporting mechanisms for program status, risks, decisions, and critical path updates
• Facilitate cross-functional communications to gather inputs, align priorities, resolve conflicts, and share project updates
• Support preparation for governance reviews and executive program presentations
• Drive disciplined change control and documentation of scope/timeline changes

Associate Director, Project Management

• Partner with IT, Finance, Legal, and other key stakeholders to ensure a strong control environment is embedded in new systems, processes, and business initiatives
• Assist in the annual SOX risk assessment and scoping process
• Lead the development and continuous improvement of ITGC documentation, controls, and testing methodologies
• Execute ITGC testing, including testing of key reports and interfaces
• Identify and evaluate deficiencies related to IT controls and provide recommendations for remediation
• Stay current on industry best practices, emerging IT risks, and regulatory developments
• Foster a culture of accountability and controls awareness
• Work closely with external service providers on ITGC audits
• Support the identification and implementation of opportunities to enhance audit effectiveness through technology

Internal Audit & SOX Manager

Vice President

• Serve as a strategic leader for the HEOR and RWE strategy
• Define global HEOR and RWE strategy integrating advanced analytics, digital health
• Drive U.S. market access priorities and support optimal reimbursement
• Oversee design and delivery of real-world studies and economic models
• Collaborate with internal and external stakeholders to align evidence generation with clinical strategy

Vice President, Health Economics and Outcomes Research

Medical Director

• Co-develop and implement the Medical Affairs strategic and integrated medical plans across their lead asset
• Through cross-functional collaboration, identify data gaps and develop and deliver an integrated evidence generation plan
• Provide scientific guidance and tactical execution for medical publication planning, medical education, medical information system development, field medical liaisons, medical communication, RWE, and HEOR
• Work closely with clinical development and regulatory professionals as well as strategic alliance partners
• Develop and maintain professional relationships with Key Opinion Leaders (physicians and researchers) and relevant professional societies to exchange scientific knowledge and to identify current and future collaboration opportunities
• Contribute to the conduct of scientific advisory boards and steering committees and partner with new product planning in executing subject matter expert focus groups in concert with Executive Director, Medical Affairs
• Execute on MA strategic imperatives and tactical plans to enhance healthcare practitioner education and improve patient outcomes
• Support preparation of clinical sections of relevant regulatory filings to Health Authorities and safety reporting in conjunction with the Executive Medical Director, Medical Affairs
• Provide medical review of training materials for medical and commercial employees; contribute to scientific affairs by authorizing and/or reviewing abstracts, presentations and manuscripts for medical and scientific accuracy and content
• Work across the organization to develop and implement publication strategies across multiple programs
• Evaluate health economics landscape in each disease area in association with HEOR and make recommendations to the outcomes research plan that can support reimbursement and commercial activity
• Work closely with commercial and clinical development in writing target product profiles in light of potential life cycle management opportunities
• Partner with Marketing, Market Access, and Commercial Operations in concert with the Executive Director, Medical Affairs, in developing Senior Management approved brand plans
• Develop, refine, and implement Medical Affairs policies and procedures and SOPs
• Partner with various functions in developing an IME/CME strategy and implement process for review and approval; provide medical review of applications for independent medical education grants
• Foster research relationships with key research centers in the US and OUS
• Interact regularly with key medical subject matter experts along with Executive Director, Medical Affairs
• Support the Medical Information function to respond to external requests for information regarding compounds in development and approved products consistent with promotional compliance and regulatory requirements
• Provide medical review or support the medical affairs review and approval of promotional and medical materials in compliance with corporate standards and government/industry regulations; partner effectively with commercial organization to develop scientifically rigorous promotional material
• Maintain up-to-date knowledge and adherence of all applicable guidance, regulation, and law that mandates the nature in which pharmaceutical organizations function.
• Other duties as assigned