Senior Medical Director, Clinical Research, Endocrinology

Crinetics Pharmaceuticals

Senior Medical Director overseeing clinical research strategies and execution for endocrine therapies. Integral role within multi-disciplinary teams in developing clinical plans and trials.

Posted 7/16/2026full-timeRemote • California • 🇺🇸 United StatesSenior💰 $324,000 - $360,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive expertise in clinical development, including the design and execution of clinical trials, regulatory compliance, and medical monitoring. Proven ability to lead cross-functional teams and collaborate with regulatory agencies to ensure successful trial outcomes.

Highest-signal resume keywords

MD Degree10+ Years Clinical Experience5+ Years Program Management ExperienceClinical Trial Design and ExecutionGCP and ICH Guidelines Knowledge

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical Development Plan (CDP) CreationTarget Product Profile (TPP) DevelopmentFirst-in-Human Study DesignPhase 2 Proof-of-Concept StudiesGlobal Phase 3 Trials ExecutionBiomarker ApplicationMedical Monitoring of Clinical Trials

Soft Skills

CollaborationLeadershipCommunication

Tools & Technologies

Electronic Data Capture (EDC)

Industry Keywords

EndocrinologyRegulatory Agencies InteractionClinical ResearchPharmacovigilanceHealth Authorities Compliance

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Clinical leader of one or more endocrinology programs, being integral to developing the clinical strategy and plans
Member of global project team(s) and development sub team(s)
Contribute as the Clinical Research expert to the conception and regular modifications of the Target Product Profile (TPP)
Lead the development of the Clinical Development Plan (CDP) for each indication being pursued, using the TPP as guidance
Define the scientific rationale and design captured in the Clinical Study Outline for each study in the CDP
Lead the discussions and oversee the writing of the study synopsis, study protocol and its amendments
Review or oversee the review of the data input in the EDC for events of interest or needing further investigation
Provide senior-level medical monitoring and safety oversight in cooperation with pharmacovigilance
Collaborate with other departments in all topics related to the conduct and analysis of clinical study results
Use the findings and other analyses to contribute to trial-related advisory boards, lead investigator meetings, protocol training meetings
Support advisory boards, key opinion leader engagement, and external scientific collaborations
Contribute to the development of relevant sections of regulatory documents such as amendments to protocols and responses to Health Authorities questions

Requirements

What you’ll need

MD degree
10+ years of experience industry, clinical/medical practice or combination
5+ years of program management experience
Experience from clinical practice in internal medicine/endocrinology
Experience in designing, planning, and executing First-in-Human studies, Phase 2 proof-of-concept studies and preferably also global phase 3 trials
Experience with application of biomarkers
Experience interacting with the FDA and/or EU regulatory agencies is a plus
Strong general knowledge of GCP, ICH guidelines and regulatory requirements and trial design
Intimate knowledge of and high-level expertise in the day-to-day medical monitoring of clinical trials

Benefits

Comp & perks

Health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance
20 days of PTO
10 paid holidays
Winter company shutdown
Discretionary annual target bonus
Stock options
401k match