Nuclera

Research Associate/Scientist, Protein Science

Nuclera

full-time

Posted on:

Origin:  • 🇬🇧 United Kingdom

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Job Level

JuniorMid-Level

About the role

  • Work on protein expression, purification, and characterisation workflows contributing to development of Nuclera’s eProtein Discovery platform
  • Follow SOPs and work under supervision to execute and analyse experiments on the eProtein Discovery System
  • Design, execute, and troubleshoot DNA preparations, protein purifications and protein activity assays with guidance from senior members of the group
  • Actively engage in scientific discussion within the group and across groups to contribute to robust product development
  • Report results in a timely manner and maintain good laboratory practices

Requirements

  • BS/MSc in protein biophysics, biochemistry, molecular biology or a related area, with 2-4 years’ (for BS) and 1 years’ (for MSc) industry experience
  • Track record of delivering robust data and high-quality results within tight timelines
  • Experience with common molecular biology techniques, including PCR, molecular cloning, and agarose gel electrophoresis
  • Experience with common protein expression and purification techniques, SDS-PAGE gel electrophoresis, and protein quantification
  • A collaborative team player with a positive can-do attitude
  • Strong problem solving capabilities, clear communication and presentation skills
  • Self-motivated interest in Nuclera’s technology
  • Right to work in the UK
  • Previous experience of making or working with proteins in the pharmaceutical, CRO, and/or biotechnology industry (desirable)
  • Prior experience in expressing and purifying antibodies (desirable)
  • Understanding the principles of cell-free protein synthesis technologies (desirable)
  • Experience in protein engineering and structure-guided design of protein variants for stability, activity, or yield (desirable)
  • Some knowledge of protein assays, characterisation and functional properties (e.g. solubility, aggregation properties, activity) (desirable)
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