Frontage Laboratories, Inc

Research Scientist

• Process Development & Scale-Up: Design, develop, and optimize scalable synthetic routes for small-molecule APIs and intermediates.
• Conduct reaction optimization, impurity profiling, and robustness studies.
• Execute demonstration/engineering batches and support kilogram-scale manufacturing campaigns.
• GMP Kilo-Lab Technical Support: Contribute to batch record drafting, process descriptions, and execute support kilogram-scale manufacturing campaigns.
• Provide on-the-floor technical support during non-GMP and GMP campaigns.
• Troubleshoot process deviations and equipment issues in real time.
• Collaborate with QA, QC, CMC Operations, EHS, and Engineering.
• Client Interaction & Project Leadership: Serve as the technical point-of-contact for client programs.
• Present data clearly, propose development strategies, and manage timelines.
• Support CMC planning, risk mitigation, and tech-transfer discussions.
• Documentation & Regulatory: Prepare process development reports, tech-transfer packages, and supporting CMC documentation.
• Ensure full compliance with non-GMP & GMP requirements and contribute to IND process sections.
• Team & Capability Development: Mentor junior chemists and contribute to building best practices in the new kilo-lab.
• Support implementation of SOPs, equipment capabilities, and continuous improvement initiatives.
• Participate in hiring and onboarding as the group expands.

Scientist, Senior, Principal