Encoded Therapeutics Inc.

Senior Manager, HRIS, Benefits & Compliance

Encoded Therapeutics Inc.

full-time

Posted on:

Location Type: Hybrid

Location: South San Francisco • California • United States

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Salary

💰 $150,000 - $205,000 per year

Job Level

Senior

About the role

  • Own the overall administration, optimization, and governance of the company’s HRIS platform, including employee lifecycle transactions, workflows, reporting, and system configuration.
  • In partnership with IT, develop and execute an HRIS roadmap that supports organizational scaling, evolving business needs, and future technology integrations.
  • Serve as the primary system administrator responsible for maintaining system functionality, troubleshooting issues, managing upgrades, and coordinating system changes.
  • Lead evaluation and implementation of new HR technologies, integrations, and automation opportunities that improve HR operations and employee experience.
  • Ensure the accuracy, integrity, and security of employee data across HR systems.
  • Partner with IT, Payroll, and Finance to maintain integrations between HRIS, payroll, equity administration, and other enterprise systems.
  • Oversee the design, administration, and communication of employee benefits programs including medical, dental, vision, life, disability, wellness, retirement plans, and leave programs.
  • Partner with leadership and external brokers to evaluate benefits strategy and ensure competitive offerings aligned with biotech industry benchmarks in the San Francisco Bay Area.
  • Manage annual open enrollment planning, implementation, and employee communications.
  • Act as the primary point of contact for benefits vendors, brokers, and third-party administrators.
  • Provide guidance to employees regarding benefit programs, eligibility, and claims escalation when necessary.
  • Ensure compliance with all applicable federal, state, and local regulations related to benefits administration and HR data management including ERISA, ACA, HIPAA, COBRA, and state leave programs.
  • Maintain compliance with California-specific employment and benefits regulations including leave programs, pay transparency requirements, and reporting obligations.
  • Oversee administration of employee leave programs including FMLA, CFRA, Pregnancy Disability Leave (PDL), California Paid Family Leave (PFL), ADA accommodations, and workers’ compensation coordination, partnering with third-party administrators and ensuring compliance with California and federal regulations while supporting employees and managers throughout the leave lifecycle.
  • Support audits and reporting requirements related to HR systems and benefits programs.
  • Maintain accurate plan documentation and required regulatory filings.
  • Continuously evaluate HR systems and benefits processes to identify opportunities for automation, efficiency, and improved employee experience.
  • Develop and maintain system documentation, standard operating procedures, and training resources.
  • Provide training and guidance to HR team members and managers on HRIS functionality and benefits processes.

Requirements

  • Bachelor’s degree in Human Resources, Business Administration, Information Systems, or related field.
  • 10+ years of progressive experience in HRIS administration and benefits management, including experience in high-growth or scaling organizations.
  • Experience supporting biotechnology, life sciences, or technology organizations strongly preferred, but not required.
  • Strong experience administering modern HRIS platforms (e.g., ADP, Workday, UKG, Rippling, or similar).
  • Demonstrated experience managing vendor relationships including benefits brokers and third-party administrators.
  • Strong knowledge of employee benefits regulations and compliance requirements.
  • Experience supporting multi-state employee populations, with strong knowledge of California employment and benefits regulations preferred.
  • Advanced analytical and problem-solving skills with the ability to translate HR data into actionable insights.
  • Strong communication and cross-functional collaboration skills.
  • HRIS, benefits, or HR certification such as CEBS, CBP, SHRM-CP/SHRM-SCP, or SPHR preferred.
  • Experience supporting HRIS implementations, system migrations, or major upgrades.
  • Experience working in companies with fewer than 500 employees or in rapid growth environments.
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
HRIS administrationbenefits managementsystem configurationdata integritycompliance managementemployee lifecycle transactionsreportingautomationvendor managementanalytical skills
Soft Skills
communicationcross-functional collaborationproblem-solvingguidancetrainingleadershiporganizational skillsemployee supportstrategic planningrelationship management
Certifications
CEBSCBPSHRM-CPSHRM-SCPSPHR