Encoded Therapeutics Inc.

Business Operations

• Partner with clinical operations, data management, and biometrics teams to author Request for Proposals (RFPs) and define vendor scopes of work.
• Lead cross-functional bid defense meetings, analyze commercial proposals, perform cost benchmarking, and provide data-driven recommendations to leadership.
• Drive the strategic selection of CROs and specialized clinical vendors, optimizing the vendor portfolio for quality, scalability, and cost-efficiency.
• Partner with Legal and the clinical development team in the drafting, negotiation, and final execution of Master Services Agreements (MSAs), Statements of Work (SOWs), Change Orders and confidentiality agreements across clinical functions.
• Design, author, and standardize SOW templates to streamline vendor onboarding, establish baseline metrics, and reduce execution cycle times.
• Manage the negotiation and execution of Clinical Trial Agreements (CTAs) and investigator budgets for sponsor-managed sites, ensuring rapid study startup.
• Manage an active change order management pipeline to rigorously track contract amendments, budget shifts, and vendor performance.
• Partner closely with study teams to proactively identify operational deviations from the original SOW, mitigating scope creep before it impacts the budget.
• Liaise between Clinical Operations and Corporate Finance to ensure financial alignment across all programs.
• Partner with the Head of Clinical Operations to build robust, multi-year clinical trial budget forecasts, lifecycle cost models, and annual operational plans.
• Support quarterly Budget vs. Actual (BVA) reviews; track investigator grant accruals and vendor pass-through costs, and accurately explain financial variances to leadership.
• Identify operational gaps and implement scalable business processes, tools, templates, and governance mechanisms to improve efficiency, transparency, compliance, and organizational effectiveness.
• Support due diligence, alliance management, and business development activities as needed.
• Champion a culture of accountability, operational rigor, collaboration, and continuous improvement across the Clinical organization.

Associate Director, Clinical Business Operations

Director

• Lead the multi-year strategy and roadmap for Encoded’s applications across all business functions.
• Work closely with stakeholders to rationalize the existing portfolio, minimizing functional duplication and consolidating on core platforms.
• Partner with functional leaders to understand priorities, translate business requirements into scalable technology solutions, and deliver implementations and enhancements that improve process efficiency, control, and user experience.
• Establish and evolve Encoded’s data strategy, including data architecture, master data, data lifecycle management, interoperability, reporting, and access controls.
• Lead the development of dashboards and reporting capabilities that enable timely, high-quality insights for operational, financial, and strategic decision-making.
• Oversee the design and evolution of integrations, connecting enterprise applications, data sources, and workflows across the organization.
• Partner with GxP teams to ensure enterprise applications and data processes support regulated operations.
• Identify, prioritize, and enable practical AI and automation use cases across business functions, with emphasis on productivity, workflow acceleration, knowledge access, reporting, and decision support, while aligning solutions to business value and risk tolerance.
• Define governance practices for data quality, stewardship, access, retention, and control documentation; partner with IT Security, Legal, Compliance and Quality stakeholders to align with privacy, SOX, and GxP-related requirements.
• Lead relationships with software vendors, implementation partners, and managed service providers; manage budgets, roadmaps, delivery quality, and platform performance.
• Build and lead a lean, high performing team of FTE and consulting resources.
• Drive adoption of new platforms and capabilities through strong communication, stakeholder alignment, training, and change management, ensuring technology investments translate into measurable business outcomes.

Senior Director, IT Applications, Data

Financial Planning and Analysis

• Strategic Financial Planning: Lead end-to-end annual operating plan, quarterly forecasting (Latest Estimate), Long Range Plan and Scenario Planning processes. Conduct rigorous sensitivity and risk analyses to guide executive decision-making. Establish Commercial Planning process, including P&L modeling, demand planning and competitive analysis.
• R&D CMC Business Partnership: Act as the dedicated finance lead for R&D and Manufacturing functions. Collaborate on complex clinical study accruals and build robust modeling frameworks to track program-level performance against budgets.
• Corporate Dashboards & KPIs: Develop and maintain corporate dashboards to track performance against key clinical, program, and operational milestones.
• Infrastructure Scaling: Build out the FP&A team’s infrastructure to enable flexible forecast modeling, streamlined management reporting, cash forecasting and clinical trial study analytics and reporting
• Corporate Development Support: Provide financial modeling and due diligence support for M&A, licensing, and clinical investment decisions
• Cross-Functional Stewardship: Serve as the financial gatekeeper for contract requests via Coupa and act as the primary System Administrator for Adaptive, ensuring the integrity of our planning tools
• Governance & Compliance: Advise internal stakeholders on corporate policies and compliance to ensure proper GAAP treatment of expenses throughout the organization.

Associate Director, Clinical Business Operations

Senior Director, IT Applications, Data

Senior Director, Financial Planning and Analysis