Eli Lilly and Company

Director/Senior Director, Analytical Methods – Methods4Insight

Eli Lilly and Company

full-time

Posted on:

Location Type: Hybrid

Location: San DiegoCaliforniaColoradoUnited States

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Salary

💰 $193,500 - $338,800 per year

Job Level

Tech Stack

About the role

  • Serve as the subject matter expert in your analytical domain, staying current on innovative methods and making informed recommendations about adoption, adaptation, or development of novel approaches.
  • Develop and deploy cutting-edge analytical methods tailored to Lilly's discovery challenges, building workflows that integrate multiple approaches (e.g., physics-based and data-driven) to harness complementary strengths.
  • Work alongside discovery project teams to translate complex scientific questions into tractable analytical problems, driving analyses that directly inform compound prioritization, design recommendations, and mechanism of action hypotheses.
  • Collaborate with Architecture4Insight to deploy analytical methods as accessible tools and agent-ready capabilities with well-defined APIs for autonomous AI decision-making.
  • Identify strategic data gaps in your domain and partner with Scale4Insight to design targeted experiments that generate data in high-value areas.
  • Establish best practices for method validation, including prospective testing against experimental outcomes, and demonstrate impact through tracked metrics: decisions influenced, hypotheses generated, and timelines accelerated.
  • Collaborate across all Data Foundry pillars and with Frontier AI to ensure analytical capabilities are fully integrated into the broader discovery ecosystem.
  • Publish peer-reviewed research, present at scientific conferences, and build analytical literacy across the organization.
  • Mentor junior computational scientists and contribute to a culture of scientific rigor, reproducibility, and continuous improvement.

Requirements

  • MS/Ph.D. in Cheminformatics, Computational Biology, Biophysics, Applied Mathematics, Computer Science, Statistics, or a related quantitative field
  • 6+ years of experience developing and applying analytical methods in drug discovery or related life sciences fields
  • Deep expertise in at least one analytical domain with demonstrated impact on scientific outcomes
  • Strong programming skills in Python, R, or similar scientific computing languages
  • Publications in peer-reviewed journals demonstrating contributions to your analytical domain
  • Ability to explain complex analytical concepts clearly to non-computational scientists
  • Track record of deploying analytical methods that influenced real scientific decisions or discoveries
  • Breadth across multiple analytical approaches, with experience both developing novel methods and adopting external approaches
  • Familiarity with software engineering practices and deploying research code in production environments
  • Experience mentoring junior scientists or managing interns/postdocs
  • Ability to communicate effectively across scientific, technical, and executive audiences
  • Passion for mentoring and empowering others.
Benefits
  • eligibility to participate in a company-sponsored 401(k)
  • pension
  • vacation benefits
  • eligibility for medical, dental, vision and prescription drug benefits
  • flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
  • life insurance and death benefits
  • certain time off and leave of absence benefits
  • well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
analytical methodsPythonRscientific computingmethod validationdata-driven approachesphysics-based approachesexperimental outcomessoftware engineering practicesdeploying research code
Soft Skills
mentoringcommunicationcollaborationscientific rigorreproducibilitycontinuous improvementexplaining complex conceptsbuilding analytical literacyinfluencing decisionsempowering others