
Senior Director – Discovery Portfolio Lead
Eli Lilly and Company
full-time
Posted on:
Location Type: Hybrid
Location: New York City • Colorado • New York • United States
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Salary
💰 $172,500 - $253,000 per year
Job Level
Tech Stack
About the role
- Manage early discovery project kickoffs ensuring that key stakeholders are engaged at the right time
- Oversee portfolio transitions between Early and Late Discovery, ensuring smooth handoffs and alignment with program objectives
- Identify cross-project dependencies, risks, and opportunities for synergy
- Monitor portfolio health metrics including timelines, milestones, and decision points for progression
- Analyze cross-project themes, learnings, and opportunities for process improvement to drive portfolio optimization
- Collaborate with Candidate Selection Leads as projects approach the candidate seeking stage to ensure that projects are ready to move to the next stage
- Develop and refine stage-gate processes that balance rigor with the flexibility required in discovery research
- Serve as primary advisor to Project Managers on early-stage programs, providing guidance on project strategy, decision frameworks, and best practices
- Support alignment between project teams and senior leadership on priorities
- Advise on risk assessment, alternative approaches, and decision criteria for program progression
- Facilitate strategic discussions on program priorities and portfolio optimization
- Lead comprehensive project management for 1-2 early discovery projects, including timeline development, milestone tracking, resource coordination, and deliverable management
- Facilitate project meetings, developing agendas, capturing minutes, and tracking action items through resolution
- Coordinate cross-functional activities across matrixed teams including biology, chemistry, translational sciences, and external collaborators
- Ensure consistency in project reporting standards and decision frameworks across teams
- Drive continuous improvement initiatives for discovery project management processes and tools
- Maintain portfolio-level calendars and ensure timely preparation of materials for key decision meetings
- Develop best practices that both maintain agility and support a decision-making framework
- Proactively manage project and portfolio communications, identifying and resolving gaps or ambiguities to maintain cross-functional alignment
- Develop integrated slide decks and presentations for leadership forums that synthesize portfolio status, trends, and actionable insights
- Foster collaborative dialogue across diverse scientific disciplines, encouraging knowledge sharing and creative problem-solving approaches
- Maintain consistent communication frameworks and reporting standards across portfolio teams
Requirements
- Bachelors degree preferably in life sciences with 15+ years of relevant experience, or Masters preferably in life sciences with 12+ years of experience, or PhD in preferably in life sciences with 10+ years of experience
- Advanced degree is highly preferred
- PMP preferred
- Experience in advisory or mentorship roles
- Must have an understanding of oncology drug discovery processes and decision criteria; small molecule and large molecule experience preferred
- Ability to think strategically and use judgement
- Excellent communication and stakeholder management across scientific and operational teams
- Experience with portfolio management tools (e.g. MS Office suite, MS Project, SharePoint, and/or SmartSheet)
Benefits
- eligibility to participate in a company-sponsored 401(k)
- pension
- vacation benefits
- eligibility for medical, dental, vision and prescription drug benefits
- flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- life insurance and death benefits
- certain time off and leave of absence benefits
- well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
portfolio managementproject managementrisk assessmentprocess improvementdecision frameworkstimeline developmentmilestone trackingresource coordinationstakeholder managementoncology drug discovery
Soft Skills
strategic thinkingjudgmentcommunicationcollaborationproblem-solvingmentorshipadvisory skillsagilityknowledge sharingfacilitation
Certifications
PMP