
Senior Manager, High-Throughput Screening Operations
dsm-firmenich
full-time
Posted on:
Location Type: Office
Location: San Diego • California • United States
Visit company websiteExplore more
Salary
💰 $132,000 - $188,000 per year
Job Level
Tech Stack
About the role
- Manage and mentor a group of four or more scientists and associates within high-throughput screening operations
- Oversee day-to-day activities in HTS and compound reformatting laboratories
- Foster a problem-solving mindset and promote innovative approaches to research challenges
- Ensure efficient scheduling and supervision of all workflow processes
- Maintain and optimize the use of screening, liquid handling, and automation instruments
- Supervise the transfer of assays from Biology to the HTS group, ensuring robustness and reproducibility
- Manage and reformat collections of compounds and natural samples for daily operations
- Monitor assay performance, identify and resolve technical issues, and ensure data integrity
- Review and analyze screening data to drive discovery program success
- Partner with Data Science and Chemistry teams to enable AI-driven operations and data analysis
- Contribute to the design and implementation of new HTS assays by staying current with emerging technologies
- Prepare and submit scientific manuscripts, patent applications, and internal reports to top peer-reviewed journals
Requirements
- Ph.D. in Molecular or Cell Biology, Neuroscience, Pharmacology, or a related field
- At least 8 years of industry experience in high-throughput screening or related settings
- Demonstrated success in leading scientific teams and managing HTS laboratory operations
- Proven record of HTS-aided small molecule discovery leading to candidate selection
- Extensive knowledge of HTS procedures, assays, compound management, and automation technologies
- Strong organizational and communication skills with a collaborative, multidisciplinary approach
- Expertise in GPCR or ion channel pharmacology and structure-function analysis, with advanced data analysis capabilities
- Experience supporting computer-aided discovery within HTS operations preferred
- Development of data analysis pipelines using R or Python strongly preferred
Benefits
- A highly creative, imaginative team culture that encourages curiosity and open-mindedness
- Support for your professional growth and development through career advancement opportunities
- Dynamic application of Machine Learning and advanced modeling in biology and chemistry
- A collaborative, results-oriented organizational culture focused on scientific excellence
- A workplace that prioritizes your safety and well-being, both physically and mentally
- Competitive pay, outstanding benefits, and a rewarding compensation program
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
high-throughput screeningcompound reformattingassay performance monitoringdata analysisautomation technologiesGPCR pharmacologyion channel pharmacologystructure-function analysisdata analysis pipelinesR
Soft Skills
mentoringproblem-solvingorganizational skillscommunication skillscollaborative approachleadershipinnovative thinkingsupervisionworkflow managementmultidisciplinary collaboration
Certifications
Ph.D. in Molecular BiologyPh.D. in Cell BiologyPh.D. in NeurosciencePh.D. in Pharmacology