dsm-firmenich

Senior Manager, High-Throughput Screening Operations

dsm-firmenich

full-time

Posted on:

Location Type: Office

Location: San DiegoCaliforniaUnited States

Visit company website

Explore more

AI Apply
Apply

Salary

💰 $132,000 - $188,000 per year

Job Level

Tech Stack

About the role

  • Manage and mentor a group of four or more scientists and associates within high-throughput screening operations
  • Oversee day-to-day activities in HTS and compound reformatting laboratories
  • Foster a problem-solving mindset and promote innovative approaches to research challenges
  • Ensure efficient scheduling and supervision of all workflow processes
  • Maintain and optimize the use of screening, liquid handling, and automation instruments
  • Supervise the transfer of assays from Biology to the HTS group, ensuring robustness and reproducibility
  • Manage and reformat collections of compounds and natural samples for daily operations
  • Monitor assay performance, identify and resolve technical issues, and ensure data integrity
  • Review and analyze screening data to drive discovery program success
  • Partner with Data Science and Chemistry teams to enable AI-driven operations and data analysis
  • Contribute to the design and implementation of new HTS assays by staying current with emerging technologies
  • Prepare and submit scientific manuscripts, patent applications, and internal reports to top peer-reviewed journals

Requirements

  • Ph.D. in Molecular or Cell Biology, Neuroscience, Pharmacology, or a related field
  • At least 8 years of industry experience in high-throughput screening or related settings
  • Demonstrated success in leading scientific teams and managing HTS laboratory operations
  • Proven record of HTS-aided small molecule discovery leading to candidate selection
  • Extensive knowledge of HTS procedures, assays, compound management, and automation technologies
  • Strong organizational and communication skills with a collaborative, multidisciplinary approach
  • Expertise in GPCR or ion channel pharmacology and structure-function analysis, with advanced data analysis capabilities
  • Experience supporting computer-aided discovery within HTS operations preferred
  • Development of data analysis pipelines using R or Python strongly preferred
Benefits
  • A highly creative, imaginative team culture that encourages curiosity and open-mindedness
  • Support for your professional growth and development through career advancement opportunities
  • Dynamic application of Machine Learning and advanced modeling in biology and chemistry
  • A collaborative, results-oriented organizational culture focused on scientific excellence
  • A workplace that prioritizes your safety and well-being, both physically and mentally
  • Competitive pay, outstanding benefits, and a rewarding compensation program
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
high-throughput screeningcompound reformattingassay performance monitoringdata analysisautomation technologiesGPCR pharmacologyion channel pharmacologystructure-function analysisdata analysis pipelinesR
Soft Skills
mentoringproblem-solvingorganizational skillscommunication skillscollaborative approachleadershipinnovative thinkingsupervisionworkflow managementmultidisciplinary collaboration
Certifications
Ph.D. in Molecular BiologyPh.D. in Cell BiologyPh.D. in NeurosciencePh.D. in Pharmacology