BridgeBio

Medical Director

• The Field Medical Director (FMD)/Sr. FMD is a field-based scientific expert responsible for communicating with a variety of internal and external stakeholders, providing medical and scientific information on the appropriate utilization of therapy(s), and advancing therapeutic disease state knowledge.
• The FMD/Sr. FMD will be experienced, working in a fast-paced, highly collaborative environment, specifically with product launch planning, rare disorders, or underdiagnosed patient populations.
• This includes developing and executing a comprehensive territory medical plan, attending conferences, delivering scientific presentations, and scientific exchange with physicians and other healthcare providers.
• This role will be critical to cultivating relationships and establishing professional collaborations with academic researchers, therapeutic area leaders, relevant research centers, organizations, and clinical care teams.
• This position reports to the National Head, Field Medical Affairs, and will require extensive travel, sometimes involving weekends.

Senior Field Medical Director

• Identify and engage with external experts and HCPs, with the goal of providing disease state awareness, genetic identification, and scientific exchange
• Advance clinical practice and improve patient outcomes by engaging key stakeholders across the assigned territory
• Cultivate strong professional relationships with KOLs and influential HCPs to support scientific exchange and medical collaboration.
• Serve as a scientific resource and strategic partner to HCPs to support patient identification and appropriate care pathways
• Establish and maintain professional relationships with a range of HCPs – including physicians, pharmacists, nurses, and other medical experts – to support disease education, product awareness, and evidence-based practice in alignment with medical strategy.
• Conduct impactful customer engagements, including discussions around emerging data, clinical trial activity, treatment barriers, market dynamics, unmet medical needs, pipeline updates, and disease state education.
• Provide medical and scientific support for internal cross-functional teams, including clinical development commercial, and market access helping to ensure alignment with external insights and evolving scientific landscapes.
• Support Clinical Development by appropriately assisting with site and investigator identification, study awareness and education and act as a field liaison for study site staff
• Support investigator-initiated research efforts and collaborate on the development of scientific publications and congress presentations.
• Participate in the planning and execution of advisory boards, speaker training programs, and medical education initiatives
• Serve as a medical and scientific expert at major medical conferences, symposia, and external stakeholder meetings.
• Collect, synthesize, and relay field-based insights to internal teams to inform clinical strategy, product development, and evidence generation plans.
• Identify opportunities to connect KOLs with appropriate BridgeBio colleagues and follow through to support ongoing collaboration and alignment.
• Ensure compliance with all internal policies and external regulatory requirements, including company travel and expense policies, institutional guidelines, and applicable local, state, and federal laws.
• Operate in full accordance with company Ethics, Compliance, and Promotional policies, fostering a culture of accountability and integrity among peers and collaborators.

Associate Director, Senior Field Medical Director – Mid-Atlantic

• Cultivating strong scientific relationships with external experts
• Delivering clinical and scientific insights
• Serving as a strategic partner to both internal teams and the broader medical community
• Building trusted partnerships with key opinion leaders (KOLs)
• Facilitating scientific exchange
• Collaborating cross-functionally to advance internal initiatives
• Providing healthcare professionals (HCP) appropriate education and information to improve patient outcomes
• Shaping and driving medical affairs tactics and operations from the ground up
• Supporting Clinical Development by appropriately assisting with site and investigator identification, study awareness, and education

Associate Director, Senior Field Medical Director – West

• Support the generation and communication of clinical and real-world evidence for AI-enabled cardiovascular solutions in ATTR-CM.
• Help advance AI-driven insights across diagnosis and disease management, with a key focus on coordinating BBIO's collaboration with Yale CarDS.
• Work cross-functionally and externally to support adoption and scientific credibility of AI initiatives.

Associate Medical Director

Associate Director, Senior Field Medical Director – Northeast

Content Writer

• Oversee the Cardiorenal Medical Writing group, including leading, training, and mentoring for effective performance
• Lead medical writing (including coordination of other Medical Writers) from concept to final product for clinical study protocols and associated forms, protocol amendments, clinical study reports, investigator brochures, and related clinical study documents
• Provide strategic leadership to study teams to direct the preparation of protocols and CSRs, submissions, and other regulatory documents, and associated public disclosure documents.
• Lead medical writing (including coordination of other Medical Writers) from concept to final product for regulatory submissions including IND applications, health agency interaction Meeting Requests, Briefing Documents, and related submissions, NDA/MAA data modules and overall submission packages, and other related documentation for initial and/or supplemental applications for marketing authorization or label expansion
• Demonstrate in-depth knowledge of regulatory writing and data disclosure requirements
• Ensure company SOPs related to document development, templates, and medical writing deliverables conform with regulatory requirements (eg, International Conference on Harmonization (ICH) and other relevant regulatory guidelines). Take ownership of processes related to documents and guide teams through these processes
• Partner with clinical development, biostatistics, and data management in the review and development of tables, figures, and listings (TFLs), and for case narrative planning
• Work closely with study teams to ensure that results and messages in clinical documents accurately reflect the data in TFLs and other data sources
• Project manage the document review process, ensuring conflicting and/or ambiguous comments are clarified and appropriately addressed in a timely and efficient manner
• Ensure documents are generated in accordance with agreed internal processes and standards, are submission-ready, and are appropriately archived in the agreed document management system
• Ensure that appropriate documented quality control (QC) checks are performed on medical writing deliverables, respond to findings, and recommend quality process improvements
• Establish Medical Writing support models and implement strategies to improve operational efficiencies. Suggest or identify modifications and improvements to document preparation processes and company templates to continuously improve quality, efficiency, and productivity. Apply relevant experience in process initiative and/or vendor management

Executive Director, Medical Writing

• Identify and engage with external experts and HCPs, with the goal of providing disease state awareness, genetic identification, and scientific exchange.
• Advance clinical practice and improve patient outcomes by engaging key stakeholders across the assigned territory.
• Cultivate strong professional relationships with KOLs and influential HCPs to support scientific exchange and medical collaboration.
• Serve as a scientific resource and strategic partner to HCPs to support patient identification and appropriate care pathways.
• Establish and maintain professional relationships with a range of HCPs – including physicians, pharmacists, nurses, and other medical experts – to support disease education, product awareness, and evidence-based practice in alignment with medical strategy.
• Conduct impactful customer engagements, including discussions around emerging data, clinical trial activity, treatment barriers, market dynamics, unmet medical needs, pipeline updates, and disease state education.
• Provide medical and scientific support for internal cross-functional teams, including clinical development, commercial, and market access helping to ensure alignment with external insights and evolving scientific landscapes.
• Support Clinical Development by appropriately assisting with site and investigator identification, study awareness and education and act as a field liaison for study site staff.
• Support investigator-initiated research efforts and collaborate on the development of scientific publications and congress presentations.
• Participate in the planning and execution of advisory boards, speaker training programs, and medical education initiatives.
• Serve as a medical and scientific expert at major medical conferences, symposia, and external stakeholder meetings.
• Collect, synthesize, and relay field-based insights to internal teams to inform clinical strategy, product development, and evidence generation plans.
• Identify opportunities to connect KOLs with appropriate BridgeBio colleagues and follow through to support ongoing collaboration and alignment.
• Ensure compliance with all internal policies and external regulatory requirements, including company travel and expense policies, institutional guidelines, and applicable local, state, and federal laws.
• Operate in full accordance with company Ethics, Compliance, and Promotional policies, fostering a culture of accountability and integrity among peers and collaborators.

Associate Director, Senior Field Medical Director – Midwest

Financial Planning and Analysis

• Be ready to absorb information at a rapid pace.
• Given the brief nature of this role, emphasis will be placed on rapidly getting interns up to speed to encourage meaningful experience.
• Learn effectively through both direction and experience in a fast-paced environment.
• Formulate and communicate novel ideas.
• Provide valuable insights and direction in their time with the company, employing their research and unique skill set to offer novel perspectives.
• Present project conclusions meaningfully and effectively to senior leadership.
• Remain accountable and maintain an “ownership mindset” over projects.
• Perform tasks in a timely manner and remain accountable to the leaders to which they report.

FP&A Summer Intern

Clinical Research

• Coordinate and drive operational activities across assigned study workstreams (e.g., start-up, enrollment, monitoring, database lock, close-out), working under the Study Lead.
• Maintain and update study trackers, timelines, and deliverable logs; proactively escalate timeline risks and propose mitigation plans.
• Manage CROs and external vendors across all phases of study start-up, conduct, and close-out, ensuring deliverables are on time, within budget, and fully compliant with GCP, SOPs, and regulatory requirements.
• Provide oversight of clinical monitoring activities, including review of monitoring visit reports and conduct monitoring oversight visits to confirm adherence to study protocols and quality standards.
• Participate in cross-functional and vendor operational meetings as required; document decisions and action items.
• Oversee site-level operational activities such as specimen management, subject visit tracking, and timely data review to identify trends, discrepancies, and potential risks.
• Contribute to site feasibility, selection, and initiation activities while supporting the development and approval of essential study documents, including monitoring plans, ICFs, CRFs, pharmacy, and laboratory manuals.
• Oversee study supply management, review site and study budgets, and evaluate CRO/vendor invoices to ensure financial accountability and transparency.
• Ensure the Trial Master File is current, accurate, and inspection-ready.
• Participate in Investigator Meetings
• Support protocol and study report development

Clinical Trial Manager

Manager

• Oversee contract development and manufacturing organizations (CDMOs) to manage analytical development and quality control (QC) activities for drug substance (DS) and product (DP)
• Manage analytical documentation (i.e., CofAs, test methods, protocols, reports, specifications, stability, and raw data) within Quality Management System (QMS)
• Support and author analytical content for CMC Regulatory content for U.S. and Rest of World dossiers
• Manage GMP stability studies and provide trend analysis in support of retest and shelf-life extension
• Manage reference standard program (i.e., qualification, storage, inventory, distribution)
• Development and approval of specifications for raw materials, intermediates, and finished product and knowledge of regulatory requirements in the setting of specifications
• Development and validation of analytical methods and verification of compendial methods
• Able to communicate results both internally and externally through oral and written updates and formal reports as necessary
• Provide analytical support for API and Drug Product process development
• Authoring of development reports, protocols, and methods
• Support quality audits as a technical representative and contribute to authoring of audit reports

Senior Manager, CMC Analytical Development

• Leads the Clinical Study Team for assigned projects; may lead one or more clinical studies, from concept to protocol, and achieve corporate objectives and key milestones such as First Patient In, Interim Analysis, Database lock, etc.
• Manage external vendors and contract research organizations, may manage internal resources such as Clinical Research Associates (CRAs) and Clinical Trial Assistants (CTAs)
• Prepare/Review/Approve study documents such as the Monitoring Manual, Study Operational Manual, Source Data Verifications Plan, and Laboratory Manual
• Coordinate and design study materials such as CRFs, patient diaries, study participation cards, and source documents.
• Manage operational activities at the study level and monitoring activities (may include routine on-site clinical monitoring) at clinical study sites to assure adherence to GCP, Standard Operating Procedures (SOPs), and study protocols
• Negotiate and manage vendor work agreements and site contracts

Senior Clinical Trial Manager – Imaging Study

• Review of analytical data for release, stability, and in-process testing at the contract manufacturing organizations in a timely manner.
• Oversight of laboratories including investigations for out of specification, out of trend, deviations, and/or anomalous results.
• Follow up with the contract laboratories to correct any deficiencies/omissions in the provided test packages.
• Submitting test packages to QA for their review and loading all data into the electronic storage program.
• Review of analytical data related to reference standard qualification, method validation and method transfer activities.
• Travel, when necessary, to analytical testing sites or other sites

Manager, QC

• Oversee the planning, execution, and delivery of clinical trial operations, potentially across multiple studies
• Provide strong matrix management and guidance to ensure teams achieve key milestones on time and with quality
• Manage study operations within budget and established timelines, ensuring compliance with GCP, SOPs, and regulatory standards
• Champion collaboration and accountability across all aspects of study delivery
• Lead trial execution strategy and operational oversight by developing and driving the study operational plan, execution approach, and vendor-governance cadence
• Oversee quality control by developing, implementing, and training on SOPs
• Responsible for developing and managing clinical trial budgets, including site agreements, forecasting, accruals, and FTE allocations
• Build and maintain strong relationships with investigators and site staff
• Provide oversight of CROs and vendors, including selection, contracting, onboarding, and performance management
• Partner with cross-functional teams to ensure efficient trial operations
• Directly manage and develop team members (as applicable) by hiring/onboarding, setting clear goals, coaching, and providing timely feedback.

Senior Clinical Trial Manager/Associate Director

Director

• Reporting to the Vice President, Quality, the Director/Sr. Director, Vendor Quality Management provides strategic and operational leadership for the qualification, oversight, and performance management of contract manufacturers (CMOs), contract laboratories, suppliers, and service providers supporting GxP activities.
• Establish and maintain a risk-based vendor qualification and requalification program
• Define vendor risk classification criteria and oversight frequency
• Oversee vendor assessments and approval processes
• Monitor vendor performance through quality metrics
• Lead vendor transition or discontinuation activities as needed
• Oversee development and maintenance of Quality Agreements
• Ensure agreements clearly define roles and responsibilities
• Align Quality Agreements with business contracts
• Periodically review and update agreements
• Establish vendor performance metrics
• Conduct Quality Business Reviews with key vendors
• Implement risk-based monitoring strategies
• Proactively identify and mitigate compliance risks
• Ensure vendor oversight documentation supports inspection readiness
• Participate in regulatory inspections
• Coordinate vendor support during inspections
• Oversee remediation related to vendor findings
• Partner with CMC, Clinical Operations, Clinical Development, Supply Chain, Commercial, Regulatory, Legal and other functions as needed
• Provide vendor compliance risk expertise during program planning
• Support new product introductions and technology transfers as needed
• Benchmark vendor oversight practices
• Drive digital enablement of vendor management systems
• Promote proactive quality culture across partner network

Director/Sr. Director, Vendor Quality Management

• Develop and drive a proactive, multi-state strategy across priority states, aligned with enterprise priorities, portfolio objectives, and commercial planning
• Identify, assess, and influence state legislation, regulations, and executive actions impacting pricing, reimbursement, Medicaid, PBM reform, 340B, newborn screening, rare disease access, and innovation policy
• Anticipate state political, legislative, and regulatory trends, translating complex developments into clear business risks, opportunities, and recommended actions for executive leadership
• Lead coordinated advocacy campaigns in priority states, integrating direct lobbying, state trade association engagement, and coalition strategy to shape outcomes before they materially affect the business
• Maintain disciplined oversight of all state lobbying and political compliance processes, ensuring all activity meets reporting requirements and that advocacy activities adhere to applicable state ethics and disclosure laws
• Leverage established relationships and strategically build BridgeBio’s engagement with governors’ offices, state legislators and regulators, Medicaid and insurance leaders, and key staff to advance the company’s state policy priorities
• Represent BridgeBio in state coalitions, and industry forums, serving as a credible and persuasive voice for the company’s positions
• Lead engagement within state trade associations and coalitions, consultants, driving aligned action on priority issues while protecting BridgeBio’s independent strategy
• This role is responsible for executing and advancing BridgeBio’s enterprise policy positions at the state level, in close coordination with the Head of Public Policy and Federal Government Affairs
• Partner with key internal stakeholders including Commercial, Market Access and Patient Advocacy to integrate state policy strategy into coverage, reimbursement, and patient access planning, ensuring advocacy efforts directly support portfolio objectives and patient access across priority states
• Advise executive leadership and cross-functional teams on state-level legislative and regulatory developments, translating state political dynamics into clear implications for pricing, reimbursement, Medicaid coverage, and patient access strategy