
Principal Data Scientist
Veracyte, Inc.
full-time
Posted on:
Location Type: Hybrid
Location: San Diego • California • United States
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Salary
💰 $182,000 - $215,000 per year
Job Level
About the role
- Lead research into novel MMAI models while closely collaborating with other machine learning experts across the computational team on strategy, study design, cohort selection, data acquisition, and data generation.
- Architect, train, and validate MMAI models integrating modalities including genomics, transcriptomics, whole-slide imaging (e.g. H&E tumor tissue slides), and clinical features for cancer prognosis, risk stratification, diagnosis, and therapy selection.
- Drive proof-of-concept and feasibility projects from definition through model development, benchmarking, interpretation, and dissemination of results.
- Design and implement pipelines for ingesting, harmonizing, and integrating diverse data modalities (including whole-slide images, RNA-seq, WGS, clinical metadata).
- Work closely with wet lab scientists, bioinformatics/data science teams, medical/clinical/pathology teams, software/data/cloud engineers, and other cross-functional teams to ensure models are biologically interpretable and clinically applicable.
- Prepare and present findings to technical and non-technical audiences, including conference abstracts and presentations, scientific publications, and internal reports.
Requirements
- Ph.D. in bioinformatics, computational biology, genomics, biostatistics, computer science, or a related field applying quantitative computational methodologies to biological/clinical problems.
- Minimum 8 years of relevant experience, with at least 5 years in an industry setting (biotech, diagnostics, or healthcare preferred).
- Demonstrated expertise in multimodal data integration, machine learning, and model development for NGS-based clinical diagnostics.
- Strong programming skills in Python, R, and SQL.
- Strong experience with cloud computing environments (AWS preferred).
- Deep knowledge of genomics, transcriptomics, digital pathology, and clinical data analysis.
- Proven track record of technical leadership, project ownership, and successful delivery of high-impact R&D projects.
- Excellent communication skills and ability to mentor and lead interdisciplinary teams.
- Strong publication record in peer-reviewed journals, including first and senior authorship.
- Preferred: Experience with advanced ML architectures (transformers, multimodal fusion, attention mechanisms).
- Familiarity with regulatory requirements (HIPAA, GDPR) and data governance in clinical research.
- Experience with medical imaging analysis and cytopathology.
- Knowledge of cancer biology, immunology, and clinical trial design.
Benefits
- Competitive compensation and benefits
- Career opportunities
- Inclusive workforce
- Discretionary bonuses/incentives
- Restricted stock units
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
MMAI modelsmultimodal data integrationmachine learningmodel developmentPythonRSQLcloud computinggenomicstranscriptomics
Soft Skills
technical leadershipproject ownershipcommunication skillsmentoringinterdisciplinary team leadership
Certifications
Ph.D. in bioinformaticsPh.D. in computational biologyPh.D. in genomicsPh.D. in biostatisticsPh.D. in computer science