
Data Scientist, Computational & Mechanistic
Thermo Fisher Scientific
full-time
Posted on:
Location Type: Office
Location: Grand Island • California • Maryland • United States
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Salary
💰 $88,000 - $116,000 per year
About the role
- Develop hybrid modeling approaches that integrate mechanistic models with machine learning to optimize cell culture media, improve media design success rates, and accelerate development timelines.
- Build intuitive, user-friendly interfaces for implementing the hybrid models and deploy web applications on AWS EC2.
- Collaborate with cross-functional teams to understand scientific and operational requirements and develop modeling solutions that optimize various aspects of the bioproduction workflow.
- Communicate results and insights effectively to interdisciplinary project teams and stakeholders.
- Provide training and mentorship to R&D scientists and junior data scientists, supporting skill development and adoption of modeling tools.
- Contribute to grant proposals and other funding initiatives to support new data science and modeling capabilities.
Requirements
- Ph.D. in Computational Biology, Bioinformatics, Mathematics, Data Science, or related field.
- M.S. with 3+ years of industry or academic experience in mechanistic modeling, machine learning, or bioproduction applications.
- Experience in stoichiometric modelling of cell metabolism including metabolic flux analysis (MFA), flux balance analysis (FBA) etc.
- Demonstrated experience in mechanistic modeling, including development and application of first-principles models such as ODE/PDE-based, kinetic, mass-balance, or systems biology models.
- Proficiency in machine learning methods such as regression, classification, neural networks, ensemble methods, or Gaussian processes.
- Hands-on experience in building hybrid (mechanistic + ML) models and applying them to complex, data-driven problems such as bioprocess optimization, systems biology, digital twins, and process control.
- Experience working with high-dimensional and time-series experimental data.
- Strong programming skills in Python, with proficiency in relevant ML and modeling libraries such as scikit-learn, TensorFlow, and PyTorch.
- Proven experience in building and deploying interactive dashboards in Python, ideally using Dash or similar frameworks.
- Experience working with cloud-based data platforms (e.g. Databricks) and proficiency with version control systems such as GitHub.
Benefits
- A choice of national medical and dental plans, and a national vision plan, including health incentive programs
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement
- At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
- Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
- Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
mechanistic modelingmachine learningstoichiometric modelingmetabolic flux analysisflux balance analysisfirst-principles modelsordinary differential equationspartial differential equationsPythondata-driven problem solving
Soft Skills
communicationcollaborationmentorshiptraininginterdisciplinary teamwork
Certifications
Ph.D. in Computational BiologyM.S. in Data Science