Thermo Fisher Scientific

Data Scientist, Computational & Mechanistic

Thermo Fisher Scientific

full-time

Posted on:

Location Type: Office

Location: Grand IslandCaliforniaMarylandUnited States

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Salary

💰 $88,000 - $116,000 per year

About the role

  • Develop hybrid modeling approaches that integrate mechanistic models with machine learning to optimize cell culture media, improve media design success rates, and accelerate development timelines.
  • Build intuitive, user-friendly interfaces for implementing the hybrid models and deploy web applications on AWS EC2.
  • Collaborate with cross-functional teams to understand scientific and operational requirements and develop modeling solutions that optimize various aspects of the bioproduction workflow.
  • Communicate results and insights effectively to interdisciplinary project teams and stakeholders.
  • Provide training and mentorship to R&D scientists and junior data scientists, supporting skill development and adoption of modeling tools.
  • Contribute to grant proposals and other funding initiatives to support new data science and modeling capabilities.

Requirements

  • Ph.D. in Computational Biology, Bioinformatics, Mathematics, Data Science, or related field.
  • M.S. with 3+ years of industry or academic experience in mechanistic modeling, machine learning, or bioproduction applications.
  • Experience in stoichiometric modelling of cell metabolism including metabolic flux analysis (MFA), flux balance analysis (FBA) etc.
  • Demonstrated experience in mechanistic modeling, including development and application of first-principles models such as ODE/PDE-based, kinetic, mass-balance, or systems biology models.
  • Proficiency in machine learning methods such as regression, classification, neural networks, ensemble methods, or Gaussian processes.
  • Hands-on experience in building hybrid (mechanistic + ML) models and applying them to complex, data-driven problems such as bioprocess optimization, systems biology, digital twins, and process control.
  • Experience working with high-dimensional and time-series experimental data.
  • Strong programming skills in Python, with proficiency in relevant ML and modeling libraries such as scikit-learn, TensorFlow, and PyTorch.
  • Proven experience in building and deploying interactive dashboards in Python, ideally using Dash or similar frameworks.
  • Experience working with cloud-based data platforms (e.g. Databricks) and proficiency with version control systems such as GitHub.
Benefits
  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
mechanistic modelingmachine learningstoichiometric modelingmetabolic flux analysisflux balance analysisfirst-principles modelsordinary differential equationspartial differential equationsPythondata-driven problem solving
Soft Skills
communicationcollaborationmentorshiptraininginterdisciplinary teamwork
Certifications
Ph.D. in Computational BiologyM.S. in Data Science