Tempus AI

Senior Data Scientist II, Real World Evidence, Pharma R&D

Tempus AI

full-time

Posted on:

Location Type: Hybrid

Location: ChicagoCaliforniaIllinoisUnited States

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Salary

💰 $130,000 - $175,000 per year

Job Level

Tech Stack

About the role

  • Lead the design and execute delivery of RWE analyses for key pharma clients
  • Responsible for translating complex drug development questions into actionable research plans that use Tempus data for trial design and outcomes research
  • Lead the derivation of complex real-world endpoints using extensive coding, demonstrating deep comprehension of Tempus clinical and molecular data structures and complexity
  • Set the technical standard for the team by implementing advanced methods in survival analysis, machine learning, and predictive modeling
  • Actively mentor more junior scientists, guiding their technical development, reviewing code, and developing tools that set best practices across the organization
  • Drive the practical adoption of LLMs and agentic tools into daily workflow
  • Own the communication of high-stakes results to both internal executives and external partners
  • Collaborate with internal product, oncology, and clinical abstraction, and real-world data science teams to continually enhance Tempus data quality, products, and analytical best practice
  • Maintain deep expertise in oncology clinical guidelines (e.g., NCCN) and emerging RWE methodologies.

Requirements

  • Advanced education in epidemiology, biostatistics, data science, public health, or related fields, to the level of either: PhD and 4+ years of additional work experience or Master’s degree and 6+ years of additional work experience
  • Expert-level proficiency in observational real-world healthcare data, specifically in designing and implementing complex time-to-event methodologies (survival analysis)
  • Track record of leading RWD analytical studies from initial scoping through to publication or dissemination
  • Proficient in using R and SQL, especially statistical tools and packages
  • Proficiency applying machine learning, LLM-based coding assistants (e.g., Copilot, Cursor) and agentic frameworks to support data analysis, code review, or scientific documentation workflows
  • Adherence to good software engineering practices (version control, modular code, documentation)
  • Experience with code review
  • Experience as a primary technical point of communication for pharma clients, with a proven ability to collaborate on study design and translate highly technical findings into strategic recommendations for senior-level stakeholders
  • Strong project leadership with excellent written and verbal communication skills
  • Experience mentoring junior scientists, providing rigorous technical review, and fostering a culture of continuous methodological improvement.
Benefits
  • incentive compensation
  • restricted stock units
  • medical and other benefits depending on the position

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard skills
survival analysismachine learningpredictive modelingobservational real-world healthcare datatime-to-event methodologiesRSQLdata analysiscode reviewstatistical tools
Soft skills
project leadershipmentoringcommunicationcollaborationtechnical reviewguidancecontinuous improvementwritten communicationverbal communicationstrategic recommendations
Certifications
PhDMaster’s degree