
Senior Data Scientist II, Real World Evidence, Pharma R&D
Tempus AI
full-time
Posted on:
Location Type: Hybrid
Location: Chicago • California • Illinois • United States
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Salary
💰 $130,000 - $175,000 per year
Job Level
Tech Stack
About the role
- Lead the design and execute delivery of RWE analyses for key pharma clients
- Responsible for translating complex drug development questions into actionable research plans that use Tempus data for trial design and outcomes research
- Lead the derivation of complex real-world endpoints using extensive coding, demonstrating deep comprehension of Tempus clinical and molecular data structures and complexity
- Set the technical standard for the team by implementing advanced methods in survival analysis, machine learning, and predictive modeling
- Actively mentor more junior scientists, guiding their technical development, reviewing code, and developing tools that set best practices across the organization
- Drive the practical adoption of LLMs and agentic tools into daily workflow
- Own the communication of high-stakes results to both internal executives and external partners
- Collaborate with internal product, oncology, and clinical abstraction, and real-world data science teams to continually enhance Tempus data quality, products, and analytical best practice
- Maintain deep expertise in oncology clinical guidelines (e.g., NCCN) and emerging RWE methodologies.
Requirements
- Advanced education in epidemiology, biostatistics, data science, public health, or related fields, to the level of either: PhD and 4+ years of additional work experience or Master’s degree and 6+ years of additional work experience
- Expert-level proficiency in observational real-world healthcare data, specifically in designing and implementing complex time-to-event methodologies (survival analysis)
- Track record of leading RWD analytical studies from initial scoping through to publication or dissemination
- Proficient in using R and SQL, especially statistical tools and packages
- Proficiency applying machine learning, LLM-based coding assistants (e.g., Copilot, Cursor) and agentic frameworks to support data analysis, code review, or scientific documentation workflows
- Adherence to good software engineering practices (version control, modular code, documentation)
- Experience with code review
- Experience as a primary technical point of communication for pharma clients, with a proven ability to collaborate on study design and translate highly technical findings into strategic recommendations for senior-level stakeholders
- Strong project leadership with excellent written and verbal communication skills
- Experience mentoring junior scientists, providing rigorous technical review, and fostering a culture of continuous methodological improvement.
Benefits
- incentive compensation
- restricted stock units
- medical and other benefits depending on the position
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
survival analysismachine learningpredictive modelingobservational real-world healthcare datatime-to-event methodologiesRSQLdata analysiscode reviewstatistical tools
Soft skills
project leadershipmentoringcommunicationcollaborationtechnical reviewguidancecontinuous improvementwritten communicationverbal communicationstrategic recommendations
Certifications
PhDMaster’s degree