
Principal Scientist – Reagent Bioinformatics
Roche
full-time
Posted on:
Location Type: Office
Location: Pleasanton • California • United States
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Salary
💰 $121,400 - $225,400 per year
Job Level
About the role
- Proactively investigate "first-in-kind" technical challenges in novel sequencing prep and applications on the new SBX platform
- Design and prototype computational tools for cutting-edge applications where standard pipelines may not apply
- Be eager to delve into internal and third-party tools to understand their assumptions and limits
- Develop a deep understanding of the interplay between reagent chemistry and data quality to recommend iterative improvements for laboratory workflows and bioinformatics pipelines
- Collaborate closely with wet lab and computational scientists on experimental design, data analysis, QC, and visualization, ensuring high-quality results are communicated clearly across the team
Requirements
- Ph.D. in Bioinformatics, Computational Biology, or a related quantitative field
- In-depth knowledge of NGS, molecular biology, human genomics, and the "why" behind various sequencing modalities
- Expertise in diverse NGS applications including single cell, spatial transcriptomics, NGS based proteomics preferred
- Proficiency in Python and workflow managers (Nextflow or Snakemake) within distributed Linux environments, with experience producing well-documented, reproducible code
- Strong desire to solve unprecedented problems and a commitment to scientific rigor, ensuring routine QC and data tasks are completed with seamless precision
- Ability to thrive in multi-disciplinary teams and communicate technical findings to audiences of varying technical backgrounds
Benefits
- A discretionary annual bonus may be available based on individual and Company performance
- Participation in a long-term incentive program
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
BioinformaticsComputational BiologyNextflowSnakemakePythonNGS applicationssingle cellspatial transcriptomicsNGS based proteomicsdata analysis
Soft Skills
problem-solvingscientific rigorcommunicationcollaborationteamworkattention to detailadaptabilityinterpersonal skillsorganizational skillscommitment
Certifications
Ph.D. in BioinformaticsPh.D. in Computational BiologyPh.D. in a related quantitative field