Principal Scientist – In Vivo Pharmacology
Novo Nordisk
full-time
Posted on:
Location Type: Office
Location: Måløv • Denmark
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Job Level
About the role
- Lead scientific excellence in obesity and diabetes research to advance target discovery, innovation, and project progression.
- Design and conduct pivotal in vivo experiments to assess pharmacokinetics, pharmacodynamics, efficacy, safety signals, and mechanism-of-action by applying state‑of‑the‑art tools.
- Develop, optimize, and implement new disease‑relevant models and methods to evaluate biological activity of new targets and modalities.
- Develop study protocols; analyse and interpret data; ensure rigorous documentation; report findings; excellent in project management and clearly communicate results to project teams, governance boards, and Global Research leadership.
- Collaborate closely within a matrix environment—partnering with internal teams, external CROs, scientific advisors, and academic centres of excellence—to deliver high-quality, decision-enabling data.
- Mentor, coach, and develop junior scientists; foster a culture of scientific rigor, innovation, and accountability.
Requirements
- PhD in pharmacology, physiology, endocrinology, metabolism or related field, with significant experience; preferably 5-10 years in pharma/biotech R&D.
- Experience in rodent obesity and Type 2 diabetes pharmacology, including hands-on study design and execution to assess body weight, food intake, energy expenditure, and body composition; familiarity with translational endpoints and model limitations is a strong plus.
- Experience advancing drug candidates in obesity or related cardiometabolic indications into development, with strong publication record and evidence of impactful decision‑making is advantageous.
- Experience of working with different therapeutic modalities and with combination strategies targeting complementary pathways will be a clear advantage.
- Experience leveraging data to guide decisions, working with digital tools, and collaborating with bioinformatics teams.
- Excellent collaboration, team player spirit, clear communication, and problem‑solving skills; fluent in written and spoken English.
Benefits
- Health insurance
- Professional development opportunities
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
pharmacokineticspharmacodynamicsin vivo experimentsstudy designdata analysisproject managementdisease-relevant modelsbiological activity evaluationdrug candidate advancementtherapeutic modalities
Soft Skills
collaborationcommunicationproblem-solvingmentoringcoachingscientific rigorinnovationaccountabilityteam player spiritclear communication
Certifications
PhD in pharmacologyPhD in physiologyPhD in endocrinologyPhD in metabolism