MSD

Senior Principal Scientist, Oncology Translational Science, Clinical Biomarkers

MSD

full-time

Posted on:

Location Type: Hybrid

Location: South San Francisco • California • Massachusetts • United States

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Salary

💰 $206,200 - $324,600 per year

Job Level

Senior

About the role

  • Identify asset-specific translational deliverables & gaps.
  • Building testable hypothesis & forming BMx strategy: collaborate across different LFs, to formulate testable clinical and translational hypotheses; and develop clinical biomarker and translational research strategy to test the hypothesis.
  • Alignment, risk mitigation & strategy implementation: align with asset development team strategy. Build critical scientific insight to identify gaps and risks, pro-actively develop mitigation plans.
  • Collaborate with Asset Development Teams, Early Development Teams; Product Development Teams, Clinical Trial Teams, Discovery, Informatics; Diagnostics, quantitative modeling team; Biostats, Molecular Assay teams, and other key LFs to author protocol-specific biomarker plans and ensure their efficient implementation.
  • Proactively identify and engage external KOL’s on specific hypothesis-driven collaborations to complement internal effort.
  • Drive the publication of biomarker and translational research for respective studies.
  • Analysis, interpretation & impact: collaborate with forementioned line functions to build formal analysis plans, participate in data analysis and interpretation.
  • Effectively communicate the study plan, update and output across different function areas to for optimal impact on projects.
  • Contribute to Health Authority engagements; Registrational Effort and Post Marketing Commitments.

Requirements

  • PH.D., M.D. or M.D./Ph.D. with a minimum of 10 years' experience in oncology biomarker studies and translational clinical research
  • Experience in clinical trial development and execution; clear strategic view on the translational needs in clinical studies;
  • experience & familiarity with experimental and bioinformatic aspects of translational research and biomarker development
  • Ability to demonstrate a broad understanding of the end-to-end drug and diagnostic development process, and specific expertise in oncology, preferably immuno-oncology
  • Track record in cross-functional, highly matrixed collaborative groups on drug discovery and/or clinical development
  • Strong interpersonal skills, as well as the ability to function in a team environment
  • A proven track record in biomedical research
  • Demonstrated record of scientific scholarship and achievement
Benefits
  • medical, dental, vision healthcare and other insurance benefits (for employee and family)
  • retirement benefits, including 401(k)
  • paid holidays
  • vacation
  • compassionate and sick days

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard skills
oncology biomarker studiestranslational clinical researchclinical trial developmentbioinformaticsdrug development processdiagnostic developmentbiomedical researchdata analysisscientific scholarshiphypothesis testing
Soft skills
interpersonal skillsteam collaborationstrategic thinkingcommunicationrisk mitigationproblem-solvingleadershipcross-functional collaborationcritical thinkingengagement
Certifications
PH.D.M.D.M.D./Ph.D.