MapLight Therapeutics, Inc.

Director, Clinical Pharmacology – Pharmacometrics

MapLight Therapeutics, Inc.

full-time

Posted on:

Location Type: Hybrid

Location: California • Massachusetts • United States

Visit company website

Explore more

✨ AI Apply
Apply

Salary

💰 $208,000 - $260,000 per year

Job Level

Lead

About the role

  • Serve as both the Clinical Pharmacology and Pharmacometrics Lead for clinical programs.
  • Apply expertise in pharmacokinetics, pharmacodynamics, and quantitative modeling to guide dose selection.
  • Collaborate with Clinical Operations, Biometrics, Regulatory Affairs, Medical Affairs, Toxicology, and Pharmacology.
  • Provide strategic input into the progression of drug candidates from pre-IND through NDA submission.
  • Design and provide input into clinical study protocols, reports, and related documentation.
  • Perform, interpret, and communicate PK and PD analyses to support dose selection and clinical decision-making.
  • Author and contribute to regulatory submissions and represent the company in interactions with global health authorities.

Requirements

  • Ph.D. in Pharmaceutical Sciences or a related discipline.
  • Formal training in Pharmacokinetics, Pharmacodynamics, and Drug Metabolism.
  • Minimum of 6 years of experience in clinical drug development, preferably with small molecules.
  • Demonstrated expertise in PK and PK/PD modeling, including recent applications using NONMEM.
  • Strong scientific communication and presentation skills.
  • Proven publication record in the field of clinical pharmacology and pharmacometrics.
Benefits
  • annual bonus opportunity
  • medical insurance
  • dental insurance
  • vision insurance
  • life insurance
  • Accidental Death & Dismemberment insurance
  • short term disability insurance
  • long term disability insurance
  • 401(K) plan with match
  • stock options
  • flexible non-accrual paid time off
  • parental leave
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
pharmacokineticspharmacodynamicsquantitative modelingPK and PD analysesPK/PD modelingNONMEMclinical study protocolsregulatory submissionsdrug metabolismclinical drug development
Soft Skills
scientific communicationpresentation skills
Certifications
Ph.D. in Pharmaceutical Sciences