Karius

Senior Software Engineer, Developer/SDET

Karius

full-time

Posted on:

Location Type: Hybrid

Location: Redwood City • California • 🇺🇸 United States

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Salary

💰 $137,725 - $206,587 per year

Job Level

Senior

Tech Stack

AWSAzureCloudDockerGoogle Cloud PlatformGraphQLKafkaKubernetesPythonSelenium

About the role

  • Software Development (Back-End Focus) - Drive the design and implementation of production software systems that power Karius’s analytical pipelines.
  • Design, build, and maintain back-end software systems spanning analytical pipelines, APIs, data processing services, and supporting infrastructure.
  • Implement scalable, reliable, and secure services for ingesting, storing, and processing large volumes of genomic data.
  • Collaborate with bioinformaticians on integrating algorithms and analytical pipelines into production systems.
  • Contribute to architecture and design reviews, emphasizing performance, reliability, and maintainability.
  • Contribute to peer code reviews, design discussions, and sprint planning as part of the team.
  • Software Testing - Build and sustain the frameworks and processes that ensure our systems meet the highest standards of reliability, performance, and compliance.
  • Develop and maintain test automation frameworks and tools (e.g., Pytest, Postman, custom command-line tooling/scripts) to ensure comprehensive coverage of unit, integration, regression, and system-level testing.
  • Translate requirements and specifications into well-structured test cases and test plans, ensuring traceability between requirements, risks, and test cases using modern tools and processes.
  • Support the execution and documentation of verification and validation (V&V) activities, ensuring compliance with regulated software development practices.
  • Advocate for testability and quality throughout the software lifecycle, helping shape designs that are easier to validate and maintain.

Requirements

  • BS or MS degree in Computer Science, Software Engineering, Electrical Engineering, Bioengineering, or a related technical field involving algorithms or coding (e.g., physics or mathematics).
  • 5+ years of experience designing, developing, and maintaining production software systems (Python preferred), ideally with experience in regulated environments (e.g., healthcare, life sciences).
  • Experience with cloud platforms (e.g., AWS, Azure, GCP) and developing distributed cloud-based systems using modern technologies and flows (e.g., Docker, Kubernetes, Git/GitHub, CI/CD, Kafka, GraphQL).
  • Experience across the full software development lifecycle, including project management, requirements traceability, and test automation using Python and modern frameworks (e.g., Pytest, Postman, Playwright, Selenium).
  • Familiarity with bioinformatics tools and genomic data formats is a strong plus.
  • Familiarity with regulations pertaining to IVD and/or LDT development (e.g., 21 CFR Part 11, 21 CFR Part 820, CAP/CLIA, NYS DOH) and related standards (e.g., IEC 62304, ISO 13485, ISO 14971) is a strong plus.

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard skills
Pythonsoftware developmenttest automationdata processingAPI developmentgenomic data processingcloud-based systemsdistributed systemsrequirements traceabilitysoftware testing
Soft skills
collaborationcommunicationdesign reviewcode reviewproject managementadvocacy for qualityproblem-solvingattention to detailteamworkadaptability
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