Karius

Data Scientist

• Own EHR data extraction specifications for the AXIS registry, including data element definitions, data dictionaries, field mappings, and site-specific translation logic across heterogeneous EHR environments.
• Serve as the primary technical liaison to site informatics and IT teams, translating clinical research data requirements into executable data queries and extraction protocols; primary experience with Epic Clarity and/or Caboodle required.
• Design and validate data extraction pipelines that ingest structured EHR data (diagnoses, medications, labs, procedures, utilization) from multiple health systems into a harmonized, analysis-ready format.
• Perform data quality assessment, anomaly detection, and cross-site consistency validation; implement processes to identify and resolve data integrity issues with sites.
• Partner closely with the biostatistics team to deliver clean, structured, well-documented datasets; support data preparation, variable derivation, and dataset specifications for statistical analysis plans.
• Collaborate with clinical operations on site onboarding for clinical site data integration, including support for data governance agreements, BAAs, and technical feasibility assessments.
• Build and maintain the registry data model, data lineage documentation, and codebook to ensure reproducibility and audit-readiness.
• Apply working knowledge of real-world data standards (OMOP CDM, HL7 FHIR, SNOMED, ICD-10, LOINC) to support data harmonization across sites with diverse EHR configurations.
• Support seamless integration between EHR data, the registry EDC, and Karius' standardized internal clinical database.
• Support broader clinical research data analytics across programs, including integrating datasets from multiple sources, building analysis-ready analytic files, and data visualization to support clinical development and biostatistics teams
• Contribute to the design of data collection strategies for future real-world evidence studies and registry expansions.

Senior Clinical Data Scientist

Director

• Consistently exceed performance expectations, driving measurable growth in test volume and account value across the assigned health system portfolio.
• Build trusted, long-term strategic relationships with executive leaders, administrators, and clinical stakeholders.
• Lead Business and Utilization Reviews with system executives, demonstrating clinical, operational, and financial ROI.
• Identify and prioritize expansion opportunities within assigned health systems, including additional sites and service lines.
• Establish Centers of Excellence and cultivate Clinical Champions to accelerate adoption and advocacy.
• Secure and manage enterprise agreements, contracts, and renewals in collaboration with Legal.
• Serve as the primary point of coordination across Sales, Medical Affairs, Marketing, Legal, and Customer Success for assigned accounts.

Director, Health Systems

Research Analyst

• Perform on-site and remote monitoring visits for assigned sites in accordance with the Clinical Monitoring Plan, ICH GCP guidelines, and applicable local regulations.
• Conduct source data verification to ensure Case Report Form (CRF) data is accurate, complete, and consistent with source documents and the protocol.
• Manage day-to-day communication with assigned sites, supporting enrollment, query resolution, and overall site performance.
• Proactively identify and document site level risks and issues, respond to study specific questions, and manage escalations through to resolution.
• Oversee the collection, review, and maintenance of essential regulatory and study documents to ensure inspection readiness.
• Collaborate closely with investigators and internal clinical teams to support effective study start up, conduct, and close out and to ensure successful trial execution.
• Oversee the execution of clinical trial activities in accordance with Good Clinical Practices.

Senior Clinical Data Scientist

Director, Health Systems

Senior Clinical Research Associate – Temporary