
Principal Data Scientist – R&D DSDH, Preclinical Sciences, Translational Safety
Johnson & Johnson
full-time
Posted on:
Location Type: Hybrid
Location: Spring House • California • Massachusetts • United States
Visit company websiteExplore more
Salary
💰 $117,000 - $201,250 per year
Job Level
About the role
- Develop and deploy ML/AI models to support safety signal detection, dose selection, PK/PD modeling, toxicology insights, and translational interpretation.
- Implement representation‑learning, predictive modeling, and multivariate analytics for datasets spanning in vivo studies, in vitro assays, exposure‑response data, and pathology information.
- Partner with scientific SMEs to design modeling strategies aligned with PSTS decision points.
- Apply model governance, versioning, and validation standards consistent with R&D AI practices.
- Build and maintain scalable data pipelines that integrate PSTS‑relevant data sources (e.g., toxicology studies, PK/PD datasets, biomarker readouts, animal study repositories).
- Transform raw experimental outputs into standardized, analysis‑ready, AI‑ready datasets using Python, R, and cloud‑native services.
- Work directly with toxicology, DMPK, and safety stakeholders to interpret scientific context and translate study designs into computational requirements.
- Collaborate with PSTS functional experts, R&D Data Science teams, and platform architects to ensure high-quality, scalable data solutions.
Requirements
- Advanced degree (MS or PhD) in Data Science, Computational Biology, Toxicology, Pharmacology, Biomedical Engineering, Computer Science, or related field.
- 3+ years of experience applying machine learning and/or data engineering to scientific or biomedical datasets.
- Proficiency with Python and/or R, SQL, and modern data engineering tooling (cloud computing, workflow orchestration, version control).
- Experience with ML model development, evaluation, and deployment pipelines.
- Experience working with biological, toxicology, PK/PD, or in vivo datasets.
Benefits
- Vacation –120 hours per calendar year
- Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
- Holiday pay, including Floating Holidays –13 days per calendar year
- Work, Personal and Family Time - up to 40 hours per calendar year
- Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
- Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
- Caregiver Leave – 80 hours in a 52-week rolling period
- Volunteer Leave – 32 hours per calendar year
- Military Spouse Time-Off – 80 hours per calendar year
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
machine learningdata engineeringpredictive modelingmultivariate analyticsmodel governanceversioningvalidation standardsdata pipelinesdata transformationcloud-native services
Soft Skills
collaborationcommunicationscientific interpretationproblem-solvingstakeholder engagement