Distinguished Scientist, Translational Safety
Johnson & Johnson
full-time
Posted on:
Location Type: Hybrid
Location: Spring House • California • Massachusetts • United States
Visit company websiteExplore more
Salary
💰 $164,000 - $282,900 per year
About the role
- Lead efforts to build and refine robust high-throughput in vitro organ specific cellular screening workflows
- Serve as the liaison between High throughput screening, Data Sciences, In Silico Modeling and Preclinical Safety Teams
- In collaboration with External Scientific Innovation and Business Development, evaluate external environment to identify new technologies, platforms & CROs with novel, cutting edge applications for in vitro toxicology
- Partner with members of Translation Safety & Discovery, Product Development and Supply (DPDS) functional groups to oversee the conversion of mechanistic cellular, molecular & biochemical toxicology assays into high throughput predictive screening assays
- Function as a key member of Global Translational Safety Team partnering with global leads to establish strategic goals and objectives
- Communicate screening plans and updates to leadership and multidisciplinary teams
- Maintain toxicology expertise through collaborations within TPPIT & PSTS globally, DPDS, and through organizational associations, literature reviews, continuing education, and publications.
- Partner with Global Lead of Cellular & Molecular Toxicology, as well as Safety Pharmacology leads to establish strategic goals and objectives.
- Identify topics appropriate for internal and external scientific publication, author scientific publications, posters and or draft documents for official communication (i.e. Contributing Scientist Reports, weight of evidence packages).
Requirements
- A minimum of a Ph.D. and postdoctoral work in Toxicology, Pharmacology, Biology or related field is required.
- A minimum of 2-5 years postdoctoral training with a total of 12+ years of relevant work experience is required.
- Demonstrated knowledge in designing and conducting mechanistic in vitro studies incorporating high throughput applications of cell-based models required.
- Experience with high throughput applications of organotypic models incorporating multiple cell types including immune cells required.
- Demonstrated knowledge of drug discovery and experience with drug modalities beyond small molecules required.
- Advanced knowledge of cellular and molecular toxicology and demonstrated experience driving projects to completion required.
- Track record of working collaboratively to solve sophisticated scientific problems required.
- Experience working on & leading highly matrixed, multi-disciplinary teams required.
- Experience with AI/ML and in silico toxicology modeling preferred.
- Board Certification in Toxicology preferred.
- Must be highly motivated, curious, and organized individual with a team-oriented mentality who enjoys working in a fast-paced, dynamic environment, and working collaboratively across functions.
- Excellent written, visual, and oral communication skills.
Benefits
- medical
- dental
- vision
- life insurance
- short- and long-term disability
- business accident insurance
- group legal insurance
- Company's consolidated retirement plan (pension)
- savings plan (401(k))
- Vacation - up to 120 hours per calendar year
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year
- Holiday pay, including Floating Holidays - up to 13 days per calendar year
- Work, Personal and Family Time - up to 40 hours per calendar year
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
in vitro toxicologyhigh throughput screeningmechanistic studiescell-based modelsorganotypic modelsdrug discoverycellular toxicologymolecular toxicologyAI/MLin silico modeling
Soft skills
collaborative problem solvingteam-oriented mentalityhighly motivatedcuriousorganizedexcellent communication skillsleadershipstrategic goal settingmultidisciplinary teamworkadaptability
Certifications
Board Certification in Toxicology