Ionis Pharmaceuticals, Inc.

Executive Director, US Value & Access

Ionis Pharmaceuticals, Inc.

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $260,000 - $296,000 per year

Job Level

Lead

About the role

  • Own the development and execution of integrated U.S. payer strategies across the Ionis commercial portfolio.
  • Establish long-range access vision, coverage objectives, and reimbursement strategies aligned with brand and corporate priorities.
  • Shape and implement enterprise-level access frameworks that can scale across current and future launches.
  • Identify, quantify, and proactively mitigate access risks and reimbursement barriers.
  • Provide forward-looking analysis of payer landscape shifts, policy changes, and competitive access dynamics.
  • Lead U.S. access readiness strategy from pre-launch planning through lifecycle optimization.
  • Oversee development of payer-facing and field access materials.
  • Ensure alignment of clinical and economic evidence generation with payer requirements in partnership with HEOR and Medical Affairs.
  • Influence economic modeling, value frameworks, and budget impact strategies to support coverage negotiations.
  • Oversee pull-through strategies to accelerate coverage adoption and minimize patient access friction.
  • Lead and develop a high-performing U.S. Value & Access organization and drive team execution to achieve measurable access outcomes.
  • Establish clear strategic priorities and ensure alignment of resources against enterprise objectives.
  • Build scalable capabilities to support portfolio expansion and future product launches.
  • Foster a culture of collaboration, accountability, and continuous improvement.
  • Partner closely with Brand, Medical Affairs, HEOR, Regulatory, Government Affairs, Pricing, Field Access, and Sales leadership to ensure cohesive execution.
  • Integrate payer insights into brand planning, evidence strategies, and lifecycle investment decisions.
  • Provide executive-level recommendations to senior leadership on reimbursement strategy and payer engagement.

Requirements

  • Bachelor’s degree required; advanced degree preferred
  • 18+ years of experience with a Bachelor’s degree (or 12+ with advanced degree) in U.S. Market Access, Value & Access, Payer Marketing, or related roles
  • Demonstrated success leading U.S. payer strategy for specialty and/or rare disease therapies.
  • Proven experience managing and building scalable, high-performing teams.
  • Deep expertise in U.S. payer systems, reimbursement policy, and access dynamics.
  • Strong executive presence with the ability to influence cross-functional and enterprise-level decision-making.
Benefits
  • Highly competitive benefits
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
U.S. Market AccessValue & AccessPayer Marketingreimbursement strategieseconomic modelingvalue frameworksbudget impact strategiesaccess frameworkspayer insightsclinical and economic evidence generation
Soft Skills
leadershipcollaborationaccountabilitycontinuous improvementinfluencestrategic prioritizationteam executionexecutive presencecross-functional decision-makingcommunication
Certifications
Bachelor’s degreeadvanced degree