Ionis Pharmaceuticals, Inc.

Operations

• Define and lead Ionis’ channel operations strategy across Specialty Pharmacies, Specialty Distributors, and other key distribution channel accounts in support of current brands, launches, and future portfolio growth.
• Own the design, governance, and continuous improvement of the end-to-end distribution channel operating model, including forecasting, inventory management, allocation, reporting, partner management, and issue escalation with assigned accounts.
• Serve as the senior Trade & Distribution lead for U.S Commercial Distribution operations in S&OP/IBP, launch readiness, and cross-functional business planning forums, ensuring channel considerations are incorporated into enterprise decisions.
• Own short-, mid-, and long-range distribution channel demand forecasting and support product and account level forecasting through integration of channel data, launch assumptions, access dynamics, and commercial insights.
• Establish distribution channel inventory strategies, targets, and guardrails, and lead recommendations on allocation decisions by balancing patient need, contractual commitments, service expectations, and commercial priorities.
• Provide strategic oversight of distribution channel inventory, ordering patterns, service performance, and other operational KPIs, and lead cross-functional action plans to address emerging risks and performance gaps.
• Develop and maintain executive-level reporting, dashboards, and business reviews that translate distribution channel performance, demand signals, and market developments into clear, actionable recommendations.
• Build and sustain senior-level relationships with external distribution channel partners and key accounts, representing Ionis as a strategic and effective manufacturer partner.
• Lead governance with distribution channel partners, including business reviews, performance management, service issue resolution, and expectations related to data, reporting, and operational execution.
• Influence channel-related contracting strategy by providing operational, service-level, inventory, and reporting perspectives during contract discussions and renewals.
• Partner closely with Supply Chain, I&A, Finance, FP&A, Brand, Market Access, Sales, Marketing, and Patient Services leaders to align distribution channel strategy with commercial objectives and business plans.
• Define policies, standards, and decision frameworks for channel operations that improve consistency, control, scalability, and readiness across products and channels.
• Apply deep understanding of the operational implications associated with pharmacy benefit and medical benefit products, including specialty pharmacy, buy-and-bill, site-of-care, and patient journey considerations.
• Lead the ongoing development of Distribution Channel Operations as a capability, including organizational structure, process design, talent strategy, and succession planning.
• Lead through direct and matrix influence to strengthen accountability, execution, and collaboration across internal stakeholders and external partners.
• Ensure distribution channel operations decisions and actions support compliance expectations, operational rigor, and Ionis’ commitment to patient access and business continuity.
• Manage work and decisions with a longer-term view, recognizing the impact of channel strategy on launches, product performance, patient experience, and enterprise results.

Director – Head of Distribution Channel Operations

Director

• Provides safety science and pharmacovigilance support to assigned molecules within Ionis portfolio
• Ensuring high quality of aggregate report production
• Development of risk management documents in collaboration with Drug Safety Physicians
• Safety review meeting coordination
• Signal detection activities as well as evaluating emerging safety data from all sources
• Identifying and managing safety signal(s)
• Authoring key sections of periodic safety reports and other PV documents
• Providing safety support for clinical development

Director, Drug Safety Surveillance – PV Scientist

Learning and Development

• Execute the Commercial L&D strategy and vision to inform the direction of the learning expectations across Ionis’ Commercial positions.
• Operationalize and execute remote and live training curricula for existing brands.
• Work cross functionally to create strategic partnerships with Sales and Marketing teams, Patient Services, Access, Medical, and other internal key stakeholders to ensure training programs and resources are in alignment with brand/company strategies and support achievement of objectives.
• Develop and manage the execution of core and role specific training curricula to support the ongoing performance improvement for all Ionis Commercial employees.
• Lead and ensure product, therapeutic, and marketplace content is current, compliant, and relevant for multiple user groups, including Sales, Field Leaders, Access, Patient Services, and other Commercial teams.
• Uphold behaviors that are in alignment with Ionis’ Culture and Core Principles.
• Effectively manage training processes and vendor projects

Director – Head of Distribution Channel Operations

Director, Drug Safety Surveillance – PV Scientist

Associate Director, Commercial Learning and Development