Ionis Pharmaceuticals, Inc.

Director

• Develop and lead U.S. market access strategies aligned with brand and portfolio objectives across a 3+ year horizon.
• Define value proposition and access roadmap from pre-launch through lifecycle management.
• Shape and implement integrated evidence plans, in partnership with HEOR and Medical Affairs to support access and payer negotiations
• Serve as the enterprise subject matter expert on access, payer dynamics, and policy trends across the landscape and within specialty and rare disease
• Oversee development of AMCP dossiers, payer communication tools (including Pre-approval Information Exchange and Payer Value Proposition) and field access tools (including product coverage, prior authorization criteria and patient support options).
• Guide economic modeling and budget impact analyses to support payer discussions
• Collaborate and partner closely with Commercial to align access strategy with brand strategy.
• Engage with Government Affairs on policy implications and advocacy priorities.
• Represent the organization in external advisory boards and industry forums.
• Monitor payer landscape, competitive dynamics, and regulatory changes to inform strategy.
• Lead, coach, and develop high-performing Market Access professionals.
• Select and retain agency partners, holding full budget authority for access strategies
• Drive cross-functional alignment in matrixed environments.

Director, Value & Access

• Develop and leverage relationships with business and clinical executives at PBMs/GPOs, National & Regional Commercial Plans.
• Responsible for the development and implementation of strategic business plans.
• Provides and presents the IONIS enterprise view of our pipeline with key decision makers at Commercial and Med D payers.

Director, National Accounts

• Assess strategic engagement and sales implications of short- and long-term actions with each payer customer and take action to move payer decisions in a direction that continue to open patient access to care with IONIS products.
• Provides and represents the IONIS enterprise view of our pipeline with key decision makers at VHA and DoD
• Collaborate with Patient Services and Chanel/Distribution to ensure reimbursement confidence and unimpeded access to all in-line brands to FDA label.
• Works closely with Value & Access, Marketing, Field Access Managers, Field Medical Directors, Government Affairs and Field Sales Leadership, to ensure consistent exchange of important payer information and messages that should be communicated.
• Provides periodic market updates to Sales Management that link important provider, payer and health care reform trends and issues as well as documents initiatives and their outcomes.

Director, Government Accounts

Compliance

• Develop and maintain the annual risk-based monitoring plan, including collaboration with third-party consultants to support execution and continuous program improvement
• Lead and execute live (in-person and virtual) and transactional/desktop monitoring in partnership with other compliance team members and third-party consultants
• Define, track, and report key performance indicators (KPIs) and key risk indicators (KRIs) to assess compliance risk trends and monitoring program effectiveness
• Analyze monitoring data to identify trends, outliers, and emerging risk signals that inform monitoring priorities
• Oversee remediation and corrective action plans, including tracking progress and ensuring timely and effective resolution of monitoring findings
• Develop and maintain monitoring dashboards and reports (e.g., Excel, Tableau, Power BI, monitoring system)
• Translate analytics and monitoring results into clear, executive-ready insights
• Support monitoring system implementation and ongoing enhancement efforts
• Partner cross-functionally with Commercial, Medical, Finance, IT, HR, and other stakeholders to align compliance activities
• Provide compliance operational guidance and support for additional compliance initiatives, as needed

Assistant Director, Compliance Operations, Monitoring Lead

Marketing

• Lead strategic Heath Care Provider (HCP) and Patient initiatives aimed to shape the AxD market, build a compelling brand, support a successful product launch, and drive brand growth
• Responsible for executing market development through HCP and Patient/Caregiver DSE with AOR and omni teams
• Create and deliver core brand elements, HCP and Patient campaigns, messaging, and core claims, ensuring alignment with strategy and complimentary to other key audience engagement plans
• Develop field sales materials and patient facing materials with consistent pull-through of aligned messages
• Partner closely with cross-functional partners and Above Brand Leads (Comm Ops, US MAx, Patient Services) to prioritize, focus, and gain alignment on the most impactful campaigns and associated messaging to deliver brand objectives
• Lead opportunities for external influence with HCPs, including speaker bureau, congress strategy and execution, and expert theaters
• Develop, evolve, and optimize non-personal promotion in close collaboration with AOR and omnichannel, including websites, media drivers, emails, etc.
• Manage materials, projects, and resources through the internal review committee process (Promotional Review Committee)
• Oversee relationships with external creative and strategic agencies/vendors to ensure execution toward business objectives
• Lead/Support the integrated strategic planning process (ISPP), including brand planning, tactical planning, and budget accountability
• Attends key medical and patient conferences and builds strong, appropriate relationships with patients and advocacy groups to understand the patient journey and support the community
• Partners with Launch Excellence and Planning (LEAP) team on Integrated Launch Plan and Launch Readiness Reviews
• Supports Launch Readiness Workstreams (Commercial, GTM, etc)

Director, Commercial – Marketing, US Neurology – Alexander Disease

• Lead strategic Heath Care Provider (HCP) and Patient initiatives aimed to shape the AxD market, build a compelling brand, support a successful product launch, and drive brand growth
• Responsible for executing market development through HCP and Patient / Caregiver DSE with AOR and omni teams
• Create and deliver core brand elements, HCP and Patient campaigns, messaging, and core claims, ensuring alignment with strategy and complimentary to other key audience engagement plans
• Develop field sales materials and patient facing materials with consistent pull-through of aligned messages
• Partner closely with cross-functional partners and Above Brand Leads (Comm Ops, US MAx, Patient Services) to prioritize, focus, and gain alignment on the most impactful campaigns and associated messaging to deliver brand objectives
• Lead opportunities for external influence with HCPs, including speaker bureau, congress strategy and execution, and expert theaters
• Develop, evolve, and optimize non-personal promotion in close collaboration with AOR and omnichannel, including websites, media drivers, emails, etc.
• Manage materials, projects, and resources through the internal review committee process (Promotional Review Committee)
• Oversee relationships with external creative and strategic agencies / vendors to ensure execution toward business objectives
• Lead / Support the integrated strategic planning process (ISPP), including brand planning, tactical planning, and budget accountability
• Attends key medical and patient conferences and builds strong, appropriate relationships with patients and advocacy groups to understand the patient journey and support the community
• Partners with Launch Excellence and Planning (LEAP) team on Integrated Launch Plan and Launch Readiness Reviews
• Supports Launch Readiness Workstreams (Commercial, GTM, etc)

Director, Commercial – US Neurology, Alexander Disease (AxD)

Operations

• Conduct deep-dive analytics to understand drivers of high performance and identify operational gaps
• Develop and monitor leading indicators to proactively surface operational risks and opportunities
• Generate actionable, forward-looking insights and recommendations beyond existing KPIs to support strategic decision-making
• Translate complex operational data into clear, compelling insights for diverse stakeholders
• Identify operational pain points and optimization opportunities aligned with overall commercial objectives
• Gather and synthesize direct and indirect feedback from internal and external customers
• Propose and help prioritize solutions that enhance current operations, partnering with functional leaders to drive execution
• Explore and pilot innovative operational approaches, leveraging the Innovation Lab and external partnerships as appropriate
• Support implementation and ongoing oversight of hub and affordability platform services
• Lead day-to-day vendor management, escalating risks and performance issues as needed, to ensure efficient, high-quality delivery of Patient Services
• Partner with cross-functional teams to ensure vendor compliance with quality, regulatory, and contractual standards
• Validate data-driven trends and insights and assess operational implications through collaboration with cross-functional execution teams
• Ensure alignment across Patient Services and Commercial Operations/Analytics on data definitions, analysis, and reporting
• Represent Patient Services in cross-functional forums, as requested

Associate Director, Patient Services – Operational Excellence

• Deliver disease state and product education regarding Ionis brand(s) and their approved indication(s) using approved training/education materials to support and empower patients/caregivers as they navigate the treatment journey
• Educate account nurses and office staff, when requested, on the role and service model of the Patient Education Manager to support patients (coordinated with other field-based representatives)
• Serve as a liaison to access teams and partners to address patient specific needs
• Contributes to and engages with cross-functional team in a highly integrated way
• Demonstrates commitment to the regional team by sharing perspectives, territory insight, and recommends strategies to integrate perspectives across patient education solutions
• Responsible for delivery of approved education programs (in person and webinar) to patients, families, and caregivers
• Participate in ongoing refinement of patient engagement strategy and educational materials to increase awareness and optimize service offerings
• Respond to customer inquiries, provide appropriate education and support and triages to available resources
• Meet documentation requirements to facilitate tracking of critical metrics
• Complete all requisite training and ensure full compliance with all applicable corporate and industry policies
• In collaboration with the Corporate Affairs teams, share advocacy insights from regional and local levels
• Identify, develop, and execute a multidisciplinary team approach for the company/disease to help execute a successful launch

Associate Director, Patient Education Manager, Great Lakes Region – IL, IN, MI, OH, KY, TN

• Clarify and share vision of the Patient Innovation Lab as a Center of Excellence for Ionis
• Showcase completed Patient Innovation Lab initiatives and define a prioritized annual roadmap aligned to Ionis business objectives
• Proactively identify actions needed to elevate awareness and value of Patient Innovation Lab with operational partners, leadership, and cross functional partners
• Actively discuss ways in which Patient Innovation Lab can support other functional areas and find opportunities to build confidence in what the Lab can deliver
• Oversee the day-to-day operations of the Innovation Lab, including vendor collaboration, project management, and cross-functional activities
• Serve as the strategic liaison between Patient Services subject matter experts and the Ionis Learning and Development team, ensuring training strategy and execution meet Patient Services and field needs
• Lead the design of training program(s), partnering with subject matter experts and Learning and Development to incorporate adult learning principles and best practices
• Proactively connect with Field and Patient Services leaders to identify continuous learning opportunities and a plan to address ongoing training needs
• Hold our key operational vendor partners accountable to delivering operational excellence
• Motivate vendor partners and Ionis’ dedicated teams to perform their best for Ionis’ programs
• Engage vendor partners in understanding and addressing operational excellence gaps
• Proactively plan for upcoming operational challenges with seamless execution

Director, Patient Services Innovation – Operational Excellence

Associate Director, Patient Education Manager – Great Lakes Region

• Support the development and execution of pricing and contracting strategies for pre-launch and in-market brands, aligned with overarching commercial goals.
• Lead the creation of clear, compelling business cases to secure Executive Leadership approval for major contracting initiatives.
• Continuously monitor market dynamics, policy changes, and competitor pricing to inform recommendations and maintain competitive advantage.
• Collaborate cross-functionally with Sales, Marketing, Finance, Government Affairs, and other teams to refine pricing and contracting strategies and ensure optimal product commercialization and profitability.
• Support the National Account Team during key customer engagements and negotiations, representing Ionis’ pricing and contracting positions as needed.
• Provide pricing and reimbursement insights to help evaluate U.S. policy and legislative developments in partnership with Government Affairs and Policy.
• Partner with Finance to support quarterly close processes, including discount forecasting, GTN analytics, and utilization by contract segment.
• Drive continuous improvement and innovation in pricing and contracting processes, tools, and governance.
• Ensure compliance with all federal, state, and company policies related to pricing, contracting, and market access activities.

Director, Pricing – Contracting

• Develop and execute regional market development plans that enhance product awareness, market readiness, and customer engagement.
• Partner with field leadership to translate national brand strategy into regional commercial objectives and measurable outcomes.
• Identify, cultivate, and maintain strategic relationships with KOLs, healthcare providers, and key accounts to support brand advocacy and patient access.
• Serve as commercial liaison across departments, ensuring consistent and compliant communication with customers and internal partners.
• Deliver impactful, field-based education on disease state, product data, and Ionis’ value proposition.
• Collaborate with Regional Sales Directors, District Managers, and Market Access teams to achieve defined regional commercial performance goals, aligned with revenue and product adoption targets.
• Analyze regional market trends, performance data, and customer insights to identify growth opportunities and adjust tactics as needed.
• Support account-level planning and coordination to ensure optimized resource deployment and goal achievement.
• Participate in the establishment and execution of Key Sales Objectives (KSOs) and other measurable performance metrics.
• Collect, synthesize, and communicate actionable market insights that inform strategic decision-making and marketing strategy.
• Identify and develop high-quality peer-to-peer educational programs that align with compliance and brand priorities.
• Evaluate the impact of field initiatives, adjusting strategies to enhance effectiveness and ROI.
• Execute all activities in full compliance with Ionis’ Code of Ethics, Field Incentive Compensation Program policies, SOPs, and all applicable laws and regulations.
• Maintain all required certifications, training, and compliance attestations as a condition of incentive eligibility.
• Collaborate with Compliance and Field Leadership to ensure all speaker programs, events, and engagements are executed according to Ionis standards.

Associate Director, Market Development

Medical Director

• Identify and forge professional peer-to-peer relationships with National, Regional, and Local key opinion leaders.
• Align and execute field activities in support of Medical Affairs Strategic plan.
• Identify and communicate research gaps, opportunities, and relevant field intelligence to inform medical strategy.
• Accelerate recruitment efforts and enhance subject retention at targeted clinical trial sites.
• Leverage expertise to enhance and broaden knowledge among field medical team colleagues.
• Attend medical/scientific meetings to represent Medical Affairs with KOLs and other HCPs, strengthen individual expertise as well as capture, integrate, and summarize information of strategic interest.
• Appropriately facilitate submission of Medical Education grants and Investigator-Initiated Research Support cross-functional colleagues (e.g., commercial, clinical operations, clinical development) in appropriate activities.
• Actively participate in relevant team meetings, organizational activities, and HQ-driven medical affairs and clinical research activities (e.g., advisory boards, publication planning, investigator meetings)
• Leveraging unique skill sets, assume lead responsibility for project work identified by Medical Affairs leadership and/or organizational priorities.

CardioMetabolic Field Medical Director

Systems Engineer

• Support the execution of business initiatives as part of the Global Product Strategy and Operations (GPSO) IT team.
• Translate business needs into well-defined requirements, data specifications, and test artifacts.
• Ensure data accuracy, process consistency, and system reliability across data pipelines, platforms, and analytics products.
• Partner closely with Data Management & Governance to support delivery of scalable, fit-for-purpose data solutions across various teams.
• Create and maintain BRDs, FRDs, user stories, acceptance criteria, workflows, and data mapping documents.