Ionis Pharmaceuticals, Inc.

Associate Director – Health Economics and Outcomes Research, HEOR, Early Stage Pipeline

Ionis Pharmaceuticals, Inc.

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $180,000 - $250,000 per year

Job Level

Senior

About the role

  • The Associate Director/ Director of Health Economics and Outcomes Research (Early Stage Pipeline) will be responsible for defining and executing early evidence generation strategies and deliverables across multiple programs.
  • Support HEOR/COA endpoint strategy from Phase 1 to 3 clinical studies ensuring inclusion of patient-centric, clinically meaningful, and economically relevant outcomes.
  • Contribute to commercial and global market access strategy to influence trial designs that meet expectations from multiple stakeholders.
  • Lead development of HTA-grade cost-effectiveness and budget-impact models to support early decision-making, identify value drivers, pricing, value dossiers, and individual country-specific submissions.
  • Contribute to global HEOR evidence-generation strategies by asset, aligning development programs with regulatory, HCP, and payer/HTA expectations.
  • Build relationships with clinical and HEOR/HTA thought leaders and academic collaborators shaping input to specific projects and methodologies, particularly in rare disease.

Requirements

  • Advanced degree(s) (MD, PhD, PharmD, MSc, MPH, or equivalent) in Health Economics, Outcomes Research, Economics, Health Services Research, Business or psychometrics.
  • Associate Director: 8+ years and a master’s degree; or a PhD with 5+ years’ experience in pharmaceutical, biotechnology, or HEOR consulting environments; rare disease or neurology/cardiometabolic experience preferred.
  • Director: 12+ years and a master’s degree; or a PhD with 8+ years’ experience in pharmaceutical, biotechnology, or HEOR consulting environments; rare disease or neurology/cardiometabolic experience preferred.
  • Excellent communicator with proven interpersonal skills and ability to influence R&D, Commercial, Medical, and Regulatory teams.
  • Strong scientific writing and oral presentation skills.
  • Travel expectation is 30%.
  • Solid, firsthand experience with analysis of HTA-grade cost-effectiveness and budget-impact models; experience with evidence development for payer/HTA early scientific advice is a plus.
Benefits
  • Highly competitive benefits
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
health economicsoutcomes researchcost-effectiveness modelsbudget-impact modelsevidence generationclinical studiesdata analysisscientific writingoral presentation
Soft Skills
communicationinterpersonal skillsinfluencecollaborationrelationship building
Certifications
MDPhDPharmDMScMPH