Director, Quantitative Clinical Pharmacologist

GSK

Quantitative Clinical Pharmacologist at GSK focusing on innovative clinical pharmacology for Infectious Disease and Oncology. Lead modeling, simulations, and support drug development initiatives.

Posted 4/17/2026full-timeUpper Providence • Massachusetts, Pennsylvania • 🇺🇸 United StatesLead💰 $183,150 - $305,250 per yearWebsite

About the role

Key responsibilities & impact

Lead key activities to progress your career in quantitative clinical pharmacology
Contribute to the design of clinical development program and support life cycle management of an asset
Provide application of Clinical Pharmacokinetic (PK), Pharmacodynamic (PD), and Modeling & Simulation (MS) principles towards efficient drug development
Predict human dose range, characterize exposure-response relationship and justify dose recommendations
Develop mathematical models to understand disease and drug pharmacodynamics
Write sections of drug development documents and clinical trial protocols

Requirements

What you’ll need

Advanced Degree in Life science such as PhD, PharmD or MD
5 years + experience in clinical pharmacokinetics, modelling & simulation and model-informed drug development including designing, analysing and reporting clinical studies
Pharmacometric experience for Oncology assets including ADCs
2 years + experience of pharmacokinetic and pharmacodynamic principles and commonly applied models
1 year + experience working with common tools for quantitative clinical pharmacology such as NONMEM, R, WINNONLIN, SIMCYP, SAS and MATLAB
1 year + experience with regulatory submission documents
1 year + experience applying appropriate FDA and ICH guidelines

Benefits

Comp & perks

health care and other insurance benefits (for employee and family)
retirement benefits
paid holidays
vacation
paid caregiver/parental and medical leave

ATS Keywords

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Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools

clinical pharmacokineticspharmacodynamicsmodeling & simulationmathematical modelingdrug developmentdose recommendationsexposure-response relationshipclinical study designdata analysisreporting

Certifications

PhDPharmDMD