
Director, Integrative Sciences
GSK
full-time
Posted on:
Location Type: Hybrid
Location: Upper Providence • Massachusetts • Pennsylvania • United States
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Salary
💰 $189,750 - $316,250 per year
Job Level
Tech Stack
About the role
- Lead innovation in emerging diagnostic technologies, including ctDNA, computational pathology, advanced imaging techniques, and multi-modal biomarker platforms, to enhance patient stratification, therapeutic targeting, and mechanism-of-action insights.
- Develop and apply oncology foundational models and AI/ML analytical approaches to complex clinical, real-world and biomarker datasets, including high-dimensional data such as single-cell transcriptomics, spatial omics, proteomics, and cfDNA.
- Serve as a subject matter expert in application of analytical methods and emerging diagnostic technologies to enable biomarker discovery and diagnostic strategies to optimize patient selection, dose determination, and combination therapy approaches with a focus on antibody-drug conjugates (ADCs).
- Oversee the integration of oncology foundational models to inform translational medicine and clinical development strategies ensuring robust interpretation, practical implementation and timely communication across matrix teams.
- Collaborate with cross-functional teams, clinical development, CPMS (Clinical Pharmacology and Modeling Simulation), Diagnostic, Translational Research, and AI/ML teams, to evaluate and apply complementary data analytics approaches for meaningful insights into complex biology.
- Lead efforts to identify, evaluate, and implement emerging technology platforms to advance diagnostic innovation and support pipeline growth.
- Provide leadership and accountability for clear and timely communication of data analysis outputs, complex analytical principles, and models to diverse stakeholders, including senior leaders and non-technical partners.
- Champion the integration of biomarker and diagnostic strategies into clinical development plans, ensuring alignment with oncology research unit and translational medicine objectives
- Drive the application of computational pathology and AI-driven image analysis to enhance diagnostic capabilities and biomarker discovery in oncology programs.
- Support the evaluation of academic partnerships and external technology platforms, ensuring alignment with Oncology Translational Medicine goals and innovation priorities.
- Contribute to due diligence efforts for business development opportunities, leveraging expertise in advanced analytics and emerging diagnostic technologies.
Requirements
- PhD degree or equivalent experience/training in computational biology, bioinformatics, machine learning, computational pathology, or a related field
- 7+ years of applied experience in Pharma/Biotech or an academic setting, with a focus on oncology research, diagnostic innovation, and biomarker analysis
- Demonstrated ability to lead and influence cross-functional teams in a matrix environment, driving alignment and delivering impactful outcomes
- Experience with emerging diagnostic platforms and technologies, including their application to translational medicine and clinical development
- Demonstrated advanced knowledge of statistical and analytical methods relevant to the analysis of complex high-dimensional heterogeneous datasets
- Experience with GitHub, development of R Shiny applications/R markdown, and working in cloud or high-performance computing (HPC) environments.
Benefits
- health care and other insurance benefits (for employee and family)
- retirement benefits
- paid holidays
- vacation
- paid caregiver/parental and medical leave
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
computational biologybioinformaticsmachine learningcomputational pathologystatistical methodsanalytical methodshigh-dimensional data analysisbiomarker analysisAI/ML analytical approachesadvanced imaging techniques
Soft Skills
leadershipinfluencecommunicationcollaborationaccountabilitycross-functional teamworkstrategic thinkingproblem-solvingtimely communicationstakeholder engagement
Certifications
PhD degree