GondolaBio

Director/Senior Director, DMPK

GondolaBio

full-time

Posted on:

Location Type: Hybrid

Location: Palo Alto • California • United States

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Salary

💰 $255,000 - $285,000 per year

Job Level

Senior

About the role

  • Work closely with cross-functional project team members.
  • Participate as a functional representative on clinical trial project teams
  • Provide guidance on project teams for candidate selection, develop and drive DMPK strategies and solve ADME-related issues
  • Design, coordinate, and interpret in vitro and in vivo DMPK studies
  • Determine PK parameters for nonclinical studies using Phoenix WinNonlin and assist with the application of modeling approaches (PK, PKPD) to support human PK and dose predictions
  • Support GLP toxicology studies, review toxicokinetic reports, and monitor regulated bioanalysis
  • Monitor bioanalytical method development, validation, sample analysis, and review/approve reports
  • Generate, analyze and present data, both orally and as written reports

Requirements

  • PhD or Pharm D. in Pharmacokinetics, Pharmaceutical Sciences, or related field with a specific focus on small molecule pharmacokinetics and metabolism with at least 5 years of relevant industry experience
  • Strong understanding of DMPK principles and drug development processes
  • Expertise in drug metabolism is desirable
  • Hands-on experience using pharmacokinetic data analysis software such as Phoenix WinNonlin
  • Able to work independently and possess excellent interpersonal skills
  • Possess effective problem-solving, oral, and written communication skills.
Benefits
  • Patient Days, where we are fortunate to hear directly from individuals living with the conditions we are seeking to impact throughout the year and learn how we can improve our efforts
  • A culture inspired by our values: put patients first, think independently, be radically transparent, every minute counts, and let the science speak
  • An unyielding commitment to always putting patients first. Learn more about how we do this here
  • A de-centralized model that enables our program teams to focus on advancing science and helping patients. Our affiliate structure is designed to eliminate bureaucracy and put decision-making power in the hands of those closest to the science
  • A place where you own the vision – both for your program and your own career path
  • A collaborative, fast-paced, data-driven environment where we inspire ourselves and each other to always perform at the top of our game
  • Access to learning and development resources to help you get in the best professional shape of your life
  • Robust and market-competitive compensation & benefits package (Base, Performance Bonus, Equity, health, welfare & retirement programs)
  • Flexible PTO
  • Rapid career advancement for strong performers
  • Potential ability to work on multiple BridgeBio Pharma programs across multiple therapeutic areas over time
  • Partnerships with leading institutions
  • Commitment to Diversity, Equity & Inclusion
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
DMPK strategiesADME-related issuesin vitro studiesin vivo studiesPK parametersmodeling approachesPKPKPDbioanalytical method developmenttoxicokinetic reports
Soft Skills
interpersonal skillsproblem-solvingoral communicationwritten communication
Certifications
PhDPharm D