Associate Scientific Director, Pharmacometrics
Biogen
full-time
Posted on:
Location Type: Remote
Location: United States
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Salary
💰 $167,000 - $230,000 per year
Job Level
About the role
- Provide pharmacometrics expertise to activities throughout the drug development lifecycle and effectively collaborate with cross functional teams
- Execute advanced pharmacometrics analyses, with emphasis on PK/PD modeling and simulation and exposure-response analysis for high priority programs
- Identify opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy and safety
- Contribute to Model Informed Drug Development (MIDD) activities to support dose selection, regimen optimization and clinical trial design
- Communicate the pharmacometrics analysis results to program teams to support data-driven decision-making process
- Mentor and guide Clinical Pharmacology and Pharmacometrics colleagues on pharmacometrics analyses methodologies
- Serve as a lead author and key contributor for pharmacometrics sections of clinical and regulatory documents
- Publish in scientific journals and present at internal and external scientific events
Requirements
- PhD in Pharmacology, Pharmacokinetics, Pharmaceutics or a related quantitative discipline.
- 5+ years of relevant industry experience applying population PK/PD and other advanced quantitative methodologies to decision making.
- Deep and extensive experience with advanced population PK/PD methodology
- Strong understanding of the clinical pharmacology principles and methodologies and their application in drug development
- Solid knowledge of the drug development process and regulatory expectations for pharmacometrics analyses
- Ability to interpret quantitative results and translate analyses into actionable program insights
- Hands-on experience with pharmacometrics software tools such as NONMEM, Monolix, and R.
- Experience with mechanistic or systems pharmacology models is a plus.
Benefits
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
pharmacokineticspharmacodynamicsPK/PD modelingexposure-response analysispopulation PK/PD methodologyquantitative methodologiesdose selectionregimen optimizationclinical trial designdata-driven decision-making
Soft Skills
collaborationmentoringcommunicationguidanceinterpretation of quantitative resultstranslating analyses into actionable insights
Certifications
PhD in PharmacologyPhD in PharmacokineticsPhD in Pharmaceutics