Zoetis

Principal Scientist, PK/PD

Zoetis

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $114,000 - $185,000 per year

Job Level

Lead

About the role

  • Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports
  • Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens
  • Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects
  • Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions
  • Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project
  • Present research results to scientific teams, management, and regulatory agencies
  • Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

Requirements

  • Ph.D in pharmacology, biochemistry, or related field with 4 or more years of relevant pharmaceutical development experience
  • DVM DACVCP or DVM Dipl. ECVPT is highly desirable
  • Proven ability to design, analyze and interpret in vivo PK and PK/PD studies
  • Experience with biotherapeutics (protein therapeutics) is highly desirable
  • Skilled in the use of PK and PK/PD analysis software such as WinNonlin, Monolix or Watson
  • Working knowledge of bioanalytical methodology
  • Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics is highly desirable
  • Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable
  • Experience interacting with regulatory agencies is highly desirable
  • Experience conducting GLP studies is desirable.
  • Must have excellent verbal & written communication skills.
  • Self-starter, able to prioritize work and work efficiently with minimal supervision.
Benefits
  • Healthcare and insurance benefits beginning on day one
  • 401K plan with a match and profit-sharing contribution from Zoetis
  • 4 weeks of vacation
  • Short-term incentive compensation
  • Long-term incentives
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
in vivo PK studiesin vivo PD studiesPK/PD modelingdose regimen optimizationbiotherapeuticsbioanalytical methodologyADA assaysimmunogenicity assessmentPBPK modelingpopulation PK modeling
Soft Skills
collaborationcommunicationscientific strategy developmentpresentation skillsself-starterprioritizationindependenceteamworkproblem-solvingadaptability
Certifications
Ph.D in pharmacologyPh.D in biochemistryDVM DACVCPDVM Dipl. ECVPT