Principal Scientist, PK/PD

Zoetis

PK/PD Principal Scientist responsible for designing and analyzing studies in veterinary medicine. Collaborating with multidisciplinary teams to advance therapeutics from research to development phases.

Posted 4/14/2026full-timeRemote • 🇺🇸 United StatesLead💰 $114,000 - $185,000 per yearWebsite

About the role

Key responsibilities & impact

Independently design and analyze in vivo PK/PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports
Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens
Collaborate with bioanalytical team to assess suitability of analytical assays and forecast analytical requirements for projects
Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms/biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions
Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project
Present research results to scientific teams, management, and regulatory agencies
Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

Requirements

What you’ll need

Ph.D in pharmacology, biochemistry, or related field with 4 or more years of relevant pharmaceutical development experience
DVM DACVCP or DVM Dipl. ECVPT is highly desirable
Proven ability to design, analyze and interpret in vivo PK and PK/PD studies
Experience with biotherapeutics (protein therapeutics) is highly desirable
Skilled in the use of PK and PK/PD analysis software such as WinNonlin, Monolix or Watson
Working knowledge of bioanalytical methodology
Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics is highly desirable
Experience in PK/PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software is highly desirable
Experience interacting with regulatory agencies is highly desirable
Experience conducting GLP studies is desirable.
Must have excellent verbal & written communication skills.
Self-starter, able to prioritize work and work efficiently with minimal supervision.

Benefits

Comp & perks

Healthcare and insurance benefits beginning on day one
401K plan with a match and profit-sharing contribution from Zoetis
4 weeks of vacation
Short-term incentive compensation
Long-term incentives

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

in vivo PK studiesin vivo PD studiesPK/PD modelingdose regimen optimizationbiotherapeuticsbioanalytical methodologyADA assaysimmunogenicity assessmentPBPK modelingpopulation PK modeling

Soft Skills

collaborationcommunicationscientific strategy developmentpresentation skillsself-starterprioritizationindependenceteamworkproblem-solvingadaptability

Certifications

Ph.D in pharmacologyPh.D in biochemistryDVM DACVCPDVM Dipl. ECVPT