Director, Commercial Accounting – FP&A

Xenon Pharmaceuticals Inc.

. Serve as the primary finance partner to the Commercial organization, providing financial leadership, guidance, and insight across pricing, payer mix, pipeline conversion, top line performance, and operating expenses .

Posted 7/17/2026full-timeBoston • Massachusetts • 🇺🇸 United StatesLead💰 $213,200 - $239,100 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in financial leadership and commercial accounting within the biotech or pharmaceutical sectors, with a strong focus on Gross-to-Net accounting, revenue recognition, and compliance with US GAAP and SOX. Proven ability to manage financial reporting, forecasting, and strategic planning while building relationships with stakeholders.

Highest-signal resume keywords

CPA CertificationGross-To-Net AccountingRevenue RecognitionFinancial Systems TransformationU.S. Pharmaceutical Distribution Models

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Financial ReportingMonthly Close ProcessesVariance AnalysisAccruals ManagementForecastingCompliance ReportingData Flow ManagementInternal Controls DevelopmentCommercial Accounting ProcessesStrategic Investment Analysis

Soft Skills

Interpersonal SkillsCommunication SkillsOrganizational SkillsTeam CollaborationStrategic Thinking

Tools & Technologies

Oracle FusionAdaptive PlanningERP ImplementationsFinance Systems

Certifications & Qualifications

CPA

Industry Keywords

BiotechPharmaceuticalCommercial LaunchPayer MixPatient Support Programs340BSpecialty Pharmacy3PLPBMsGPOs

Tech Stack

Tools & technologies

ERPOracle

About the role

Key responsibilities & impact

Serve as the primary finance partner to the Commercial organization, providing financial leadership, guidance, and insight across pricing, payer mix, pipeline conversion, top line performance, and operating expenses
Design, implement, and maintain GTN reserve methodologies, including documentation of reasonable assumptions: commercial and government rebates, chargebacks, copay and patient assistance programs, distribution service fees, returns and other variable consideration
Responsible for monthly close processes for revenue, GTN, and operating expenses including journal entries, account reconciliations, true ups, and variance analysis
Lead all financial reporting initiatives for the Commercial function, including accruals and monthly and quarterly reporting of financial results for management and department heads
Manage the quarterly forecasting process by partnering with department managers to align the forecast with the most current business assumptions; ensure alignment between Commercial revenue forecast and guidance and report against such guidance, including analysis of pricing actions, margin dynamics, and market trends
Manage government pricing reporting and ensure appropriate compliance with regulatory requirements
Work within finance systems to implement or enhance systems to address planning and reporting needs of commercial accounting and GTN processes
Establish and maintain scalable data flows with 3PLs and other parties; review data provided by external parties for completeness, accuracy, and reasonable
Build SOX compliant internal controls, policies, and SOPs in preparation for commercial launch and first audit cycles
Serve as the primary commercial accounting contact for external auditors
Prepare analysis, commentary, and presentation materials for monthly and quarterly financial reviews, including executive leadership and Board of Directors meetings
Partner with Commercial team on long range planning, pricing strategy, and strategic investment analysis related to commercial growth opportunities
Develop and propose short- and long-term objectives for the function in accordance with overall Company strategies and plans
Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports
Other duties as assigned

Requirements

What you’ll need

Professional designation (CPA or equivalent) is required, technical training with Big Four CPA firm or large regional CPA firm preferred
10+ years of progressive finance and/or accounting experience with significant biotech or pharmaceutical commercial exposure
Demonstrated experience supporting at least one successful first commercial product launch and experience with designing commercial accounting processes under US GAAP and SOX environment
Strong expertise in Gross-to-Net accounting, revenue recognition, and government pricing
Strong knowledge of U.S. pharmaceutical distribution models, including specialty pharmacy, specialty distributor, 3PL, PBMs, GPOs, patient support programs, and 340B
Experience in ERP implementations or financial systems transformation initiatives; experience with Oracle Fusion and Adaptive Planning is a bonus
Proven experience building strong relationships with internal stakeholders and external service providers
Excellent organizational skills and the ability to manage concurrent deliverables and work effectively in a challenging, high performance, team environment
Exceptional interpersonal and communication skills (written and oral); communicates in a clear, concise and organized manner; listens and works collaboratively with others outside of Finance to obtain information
Able to think and act strategically, anticipate road-blocks and map out next steps in support of a fast-growing company
Self‐motivated, with initiative and the ability to take ownership of, and drive projects from start to finish
Demonstrated high level of integrity and ethics.

Benefits

Comp & perks

Our Total Rewards program includes base salary, target bonus, and stock options
Medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs
Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions
Time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown
Expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees