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Xenon Pharmaceuticals Inc.

Director, Pricing & Contracting

Xenon Pharmaceuticals Inc.

Director, Pricing and Contracting managing U.S. pricing strategy across payer organizations and market access at Xenon Pharmaceuticals.

Posted 4/24/2026full-timeBoston • Massachusetts • 🇺🇸 United StatesLead💰 $236,708 - $260,200 per yearWebsite

About the role

Key responsibilities & impact
  • Lead the development and execution of U.S. pricing strategy, including launch price recommendations and lifecycle pricing management
  • Design and implement payer contracting strategies, including rebate structures and contracting frameworks with pharmacy benefit managers (PBMs), national payer organizations, and regional health plans
  • Support contract negotiations and ensure pricing and rebate strategies align with payer coverage objectives
  • Lead financial modeling and pricing scenario analyses to evaluate the impact of pricing and contracting strategies on market access, reimbursement, and overall company financial performance
  • Develop and manage gross-to-net (GTN) models that support financial forecasting, access strategy decisions, and pricing scenario planning
  • Collaborate closely with Finance to ensure pricing assumptions, GTN forecasts, and contracting scenarios are accurately reflected in financial planning and forecasting models
  • Monitor payer contracting trends, competitive pricing dynamics, and reimbursement environments to inform pricing strategy and market access planning
  • Provide strategic oversight of government pricing considerations, including AMP, Best Price, Medicaid rebate implications, and 340B pricing impacts, ensuring pricing and contracting strategies align with regulatory requirements
  • Support the development of pricing governance processes and provide strategic recommendations to senior leadership regarding pricing decisions and contracting strategies
  • Partner with Legal and Compliance to ensure pricing and contracting practices adhere to regulatory requirements and company compliance standards
  • Develop and propose short- and long-term objectives for the function in accordance with overall Company strategies and plans
  • Plan and manage budget proposals and approved budgets in accordance with the Company’s strategic and operating plans and Finance policies
  • Recruit, lead, direct, develop, coach and evaluate direct reports, if any, in accordance with the Company’s Human Resource policies and practices
  • Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any
  • Some international travel may be required
  • Other duties as assigned

Requirements

What you’ll need
  • Bachelor’s degree required; advanced degree or MBA preferred
  • 10+ years of experience in the pharmaceutical or biotechnology industry, including at least 5 plus years in Pricing, Contracting, or Market Access roles
  • Demonstrated experience developing U.S. pricing strategy, including launch pricing recommendations and lifecycle pricing management for specialty-lite and/or specialty therapies
  • Proven experience developing and managing gross-to-net (GTN) models to support financial forecasting, pricing scenario planning, and contracting strategy
  • Demonstrated experience designing and implementing payer contracting strategies, including rebate structures and negotiations with pharmacy benefit managers (PBMs), national payer organizations, government payers and regional health plans
  • Experience evaluating government pricing implications including AMP, Best Price, Medicaid rebate exposure, and 340B pricing considerations
  • Experience supporting product launches or late-stage pipeline assets strongly preferred
  • Strong financial modeling and analytical skills with the ability to translate complex pricing and contracting scenarios into strategic recommendations
  • Demonstrated ability to collaborate cross-functionally with Finance, Legal, Compliance, Medical Affairs, and Commercial teams
  • Experience supporting pricing governance processes and cross-functional pricing decision frameworks preferred
  • Strong leadership, communication, and executive presentation skills
  • Ability to thrive in a fast-paced, growth-stage environment.

Benefits

Comp & perks
  • medical
  • dental
  • vision
  • short-& long-term disability
  • accidental death & dismemberment
  • life insurance programs
  • Employee Assistance Program
  • travel insurance
  • retirement savings programs with company matching contributions
  • vacation
  • personal days
  • sick days
  • end-of-year company shutdown
  • employee development

ATS Keywords

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Hard Skills & Tools
U.S. pricing strategylifecycle pricing managementpayer contracting strategiesrebate structuresfinancial modelinggross-to-net (GTN) modelspricing scenario planninggovernment pricing implicationscontract negotiationspricing governance processes
Soft Skills
leadershipcommunicationanalytical skillscollaborationstrategic recommendationscoachingexecutive presentation skillsability to thrive in fast-paced environments
Certifications
Bachelor’s degreeMBA