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University of Wisconsin-Madison

Scientist III – Wastewater Virome Genomic Surveillance

University of Wisconsin-Madison

Scientific lead in genome-resolved characterization of wastewater virome for the Lungfish surveillance program. Develop methodologies and manage project timelines and partner deliverables.

Posted 7/21/2026full-timeRemote • Wisconsin • 🇺🇸 United StatesMid-LevelSenior💰 $95,000 per yearWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in genome-resolved metagenomics and high-throughput sequencing workflows, with a strong focus on viral detection and characterization from low-biomass samples. Proven ability to lead research projects, secure funding, and mentor junior staff while effectively communicating complex scientific information.

Highest-signal resume keywords
Genome-Resolved MetagenomicsHigh-Throughput Sequencing WorkflowsProject LeadershipBioinformatics Pipeline DevelopmentWastewater-Based Epidemiology

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Genome-Resolved InterpretationShotgun Metagenomic SequencingProbe-Capture EnrichmentPython ProgrammingR ProgrammingLinux EnvironmentHigh-Performance ComputingData AnalysisResearch Methodology DevelopmentGrant Writing
Soft Skills
Excellent CommunicationStrong Organizational SkillsMentoringCollaborationProblem Solving
Certifications & Qualifications
PhD in MicrobiologyPhD in VirologyPhD in Molecular BiologyPhD in Genetics/GenomicsPhD in Environmental Microbiology
Industry Keywords
Viral CharacterizationEnvironmental Pathogen SurveillanceResearch FundingSample LogisticsPeer-Reviewed Publications

Tech Stack

Tools & technologies
AssemblyLinuxPython

About the role

Key responsibilities & impact
  • Serve as the computational lead for detecting and characterizing known and emerging viruses from complex, low-biomass samples while managing project timelines and partner deliverables.
  • Attend and assist with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information.
  • Identify, write, or assist in developing grant opportunities, grant applications, and proposals to secure research funding.
  • Supervise the day-to-day activities of a research unit and staff and resolve routine personnel issues.
  • Lead genome-resolved metagenomic characterization of the wastewater and environmental virome, including ultra-deep untargeted (shotgun) sequencing and targeted probe-capture/hybrid-capture enrichment of priority and emerging viruses, and develop and validate the associated low-biomass nucleic-acid recovery and sequencing-library workflows.
  • Identify research problems and develop highly complex research methodologies and procedures.
  • Publish and present results to help advance research.
  • Serve as scientific and project-management lead for the wastewater virome-surveillance program — coordinating sample logistics and timelines across partner sites and funders, and supervising and mentoring a Research Specialist and junior scientific staff.
  • Serve as an institutional subject matter expert and liaison with key internal and external stakeholders providing expert level information and representing the interests of a specialized research area.
  • Collect and analyze highly complex research data, conduct experiments and interviews, and document results according to established policies and procedures.
  • Partner with the lab’s bioinformatics group and external collaborators (including the ORCHARDS team and multi-campus wastewater-surveillance networks) to co-develop and implement improved methods for low-input viral recovery, sequencing, and downstream analysis, and establish SOPs, QC, and standardized data-return systems.
  • Conduct literature reviews, prepare reports and materials and disseminate information to appropriate entities.

Requirements

What you’ll need
  • Demonstrated expertise in genome-resolved metagenomics / metaomics of complex microbial or viral communities, including assembly, binning/classification, and genome-resolved interpretation of high-throughput sequencing data.
  • The successful applicant will likely have a track record of characterizing at least 5,000 novel viruses from complex samples.
  • PhD in microbiology, virology, molecular biology, genetics/genomics, environmental microbiology, or a closely related field, with an outstanding track record of peer-reviewed first- or corresponding-author publications, preprints, and conference presentations.
  • Documented experience developing, benchmarking, and validating both untargeted (shotgun metagenomic) and targeted (probe-capture / hybrid-capture enrichment) high-throughput viral sequencing workflows from low-biomass or environmentally derived samples and using computational tools to assess these benchmarking experiments.
  • Demonstrated experience developing or substantially adapting bioinformatic pipelines for pathogen detection and characterization in HTS data, including programming in Python and/or R and working in Linux / high-performance computing (HPC/HTC) environments.
  • Experience with wastewater-based epidemiology or environmental pathogen surveillance, including sample concentration and viral-recovery methods.
  • Demonstrated independent project leadership: coordinating multi-step laboratory and computational workflows, managing large sample sets, and meeting funder/stakeholder deliverables on defined timelines.
  • Experience supervising or mentoring junior scientists, technical staff, and/or students.
  • Track record of securing or substantially contributing to competitive research funding (e.g., lead or co-author on funded grant proposals).
  • Excellent written and verbal communication and strong organizational skills.

Benefits

Comp & perks
  • generous vacation, holidays, and sick leave
  • competitive insurances and savings accounts
  • retirement benefits