Bioinformatics Engineer – Nextflow, AWS Specialist
Twist Bioscience
contract
Posted on:
Location Type: Remote
Location: Remote • 🇺🇸 United States
Visit company websiteJob Level
Mid-LevelSenior
Tech Stack
AWSCloudDockerLinuxPython
About the role
- Architect and develop advanced Nextflow pipelines for NGS data processing, analysis, and multi-step workflow orchestration.
- Deploy, operate, and optimize pipelines on AWS EKS and Batch.
- Build and maintain Docker-based container environments for reproducible and portable bioinformatics pipelines.
- Develop and maintain robust Python tooling to support workflow automation, QC reporting, monitoring, and data integration.
- Implement workflow observability, logging, and cost-optimized execution strategies for large-scale genomic data.
- Collaborate with sequencing, bioinformatics, and platform engineering teams to improve workflow reliability and performance.
- Establish best practices for pipeline versioning, continuous integration, automated testing, and cloud-based deployment.
- Ensure pipelines are highly reproducible, fault-tolerant, and suitable for production environments in regulated or high-stakes settings.
Requirements
- 5+ years of experience in bioinformatics, computational biology, workflow engineering, or related fields.
- Expert-level proficiency in Nextflow, including DSL2, modules, workflow optimization, and pipeline debugging.
- Strong hands-on experience with AWS, particularly:
- Deep expertise with Docker, including custom image creation, multi-stage builds, and best practices for pipeline reproducibility.
- Strong Python development skills with production-level experience, testing frameworks, packaging, and tooling.
- Experience operating in cloud-native environments with distributed computing, autoscaling, cost-optimization, and workflow orchestration.
- Solid understanding of NGS data formats, sequencing workflows, and common bioinformatics tools.
- Strong Linux skills and experience with CI/CD systems.
Benefits
- Equal Opportunity Employer
- Work in service of people changing the world for the better
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
NextflowPythonDockerAWSCI/CDNGS data processingworkflow orchestrationworkflow optimizationpipeline debuggingcloud-native environments
Soft skills
collaborationcommunicationproblem-solvingattention to detailadaptability