Senior AI Applications Engineer

Twin Health

Senior AI Applications Engineer shaping AI-driven solutions for Twin Health's metabolic health initiatives. Collaborating with diverse teams to enhance personalized member experiences and improve clinical decision-making.

Posted 7/10/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $195,000 - $210,000 per yearWebsite

Tech Stack

Tools & technologies

JavaMicroservicesMySQLPostgresPythonSpringSpring BootSpringBootSQL

About the role

Key responsibilities & impact

Lead the design, development, and deployment of sophisticated AI agents and tools that streamline clinical decision-making, automate complex administrative tasks, and enhance clinical workflows.
Explore and implement the full-stack architecture required for AI-agentic systems, from context engineering, MCP servers, to API design and deployment.
Architect and build robust, scalable backend services and integrations (using Python, Java Spring Boot, SQL) that serve as the foundation for our AI applications.
Collaborate with cross-functional teams to shape the user experience of AI systems, translating clinical and operational needs into concrete technical specifications and prototypes.
Champion best practices for developing reliable, secure, and scalable AI applications, ensuring all solutions meet compliance standards such as HIPAA.
Mentor and coach other engineers, modeling cross-functional thinking and helping to elevate the team’s capabilities in building AI-driven products.
Monitor and optimize the performance of AI systems in production to handle rapid growth and ensure a seamless user experience.
Take on additional responsibilities as needed, including on-call rotations.
Regular travel to our Menlo Park headquarters for planning workshops and team collaboration sessions.
Other duties as assigned.

Requirements

What you’ll need

Bachelor’s degree in Computer Science or a STEM-related field (Master’s preferred).
5+ years of software engineering experience, with a strong foundation in building backend services.
Demonstrated experience in developing and deploying AI-powered applications using Large Language Models (LLMs) like GPT, Claude, or Gemini.
Strong practical knowledge of prompt engineering, vector databases, Retrieval-Augmented Generation (RAG), and other techniques for building reliable LLM-based systems.
Proficiency in Java and/or Python and experience developing microservices.
Hands-on experience with SQL databases (PostgreSQL, MySQL) and query optimization.
Proven ability to work across disciplines, collaborating effectively with product, design, and non-technical stakeholders to build user-centric solutions.
Excellent communication skills and a demonstrated ability to navigate ambiguity and drive projects from concept to completion.
Experience in healthcare, biosensors, or related fields is a plus but not required.
This remote opportunity based out of the U.S. Applicants must be authorized to work for any employer in the U.S.

Benefits

Comp & perks

A competitive compensation package in line with leading technology companies
A remote and accomplished global team
Opportunity for equity participation
Unlimited vacation with manager approval
16 weeks of 100% paid parental leave for delivering parents; 8 weeks of 100% paid parental leave for non-delivering parents
100% Employer sponsored healthcare, dental, and vision for you, and 80% coverage for your family; Health Savings Account and Flexible Spending Account options
401k retirement savings plan

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

PythonJavaSQLPostgreSQLMySQLAPI DesignVector DatabasesRetrieval-Augmented Generation (RAG)Software EngineeringQuery Optimization

Soft Skills

Excellent CommunicationCross-Functional CollaborationProblem-SolvingMentoringNavigating Ambiguity

Certifications

Bachelor’s Degree in Computer ScienceMaster’s Degree Preferred