Director, Translational Pharmacology

Travere Therapeutics

Director of Translational Pharmacology at Travere Therapeutics focused on drug development for rare disease therapies. Collaborating with diverse teams for innovative solutions and impactful outcomes.

Posted 7/17/2026full-timeSan Diego • California • 🇺🇸 United StatesLead💰 $189,000 - $246,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in pharmacology, translational medicine, and clinical development, with a strong focus on evaluating drug candidates and their mechanisms of action. Proven ability to synthesize complex data and communicate strategic recommendations in a collaborative biopharmaceutical environment.

Highest-signal resume keywords

Pharmacology PrinciplesTranslational MedicineRegulatory RequirementsScientific LeadershipData Synthesis and Communication

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

PharmacologyTranslational BiologyBiochemistryMolecular BiologyClinical DevelopmentNonclinical DevelopmentBiomarker StrategyMechanism of Action EvaluationDrug Candidate EvaluationToxicology Data Interpretation

Soft Skills

CollaborationCommunicationOrganizational SkillsScientific CuriosityInfluencing Skills

Certifications & Qualifications

PhDMDPharmD

Industry Keywords

Biopharmaceutical IndustryClinical Development ProgramsDiligence ActivitiesPatient ImpactEmerging Technologies

About the role

Key responsibilities & impact

Serve as a preclinical biology lead or key scientific contributor for evaluation of business development opportunities ranging from small-molecule to biologics at all stages of development, including external assets, platform-based technologies and research-based collaborations.
Assess scientific rationale, mechanism of action, disease biology, pharmacology and toxicology data, translational relevance and therapeutic safety window, biomarker strategy, and development feasibility for potential opportunities.
Review and interpret nonclinical and translational data alongside clinical, regulatory, and competitive information to identify strengths, risks, gaps, and key value drivers.
Partner with Business Development and cross-functional diligence teams to develop scientific assessment reports, diligence questions, risk summaries, and recommendations.
Identify critical experiments, analyses, or expert input needed to reduce scientific uncertainty for potential opportunities.
Support evaluation of strategic fit with Travere’s portfolio, therapeutic areas of interest, rare disease focus, and translational development capabilities.
Provide translational pharmacology expertise across preclinical and clinical-stage opportunities, including interpretation of in vitro, in vivo, ex vivo, biomarker, pharmacodynamic, and clinical pharmacology data.
Evaluate whether available pharmacology and translational data support proposed mechanisms of action, target engagement, dose rationale, patient selection, and clinical development strategy.
Integrate mechanistic biology, pharmacology, biomarker, and clinical observations to assess therapeutic potential and development risk.
Stay abreast of industry trends, emerging technologies, advances in disease biology and therapeutic targets and competitive activities to inform search strategies and evaluations relevant to Travere’s areas of interest.
Lead or contribute to scientific interactions with external companies, academic collaborators, CROs, consultants, key opinion leaders, and subject matter experts during diligence and collaboration activities.
Identify and engage external experts to inform evaluation of disease biology, pharmacology, biomarkers, clinical translation, and development risk.
Support assessment of external research proposals, collaboration opportunities, and emerging scientific areas relevant to Travere’s strategic interests.
Interpret pharmacology, toxicology, translational, and biomarker data in the context of potential clinical development and regulatory expectations.
Contribute to evaluation of whether available nonclinical packages are adequate to support current or proposed clinical development plans.
Contribute to development plans and budget for selected opportunities, including translational strategy, nonclinical pharmacology and safety needs, biomarker plans, and early clinical development considerations.
Support preparation and review of relevant sections of investigator brochures, briefing documents, regulatory submissions, and development-related documents as needed.
Provide scientific leadership within a collaborative, matrixed Research and Nonclinical Development organization.

Requirements

What you’ll need

Bachelor’s Degree in Life Science or other related discipline required
PhD, MD, PharmD, or equivalent advanced degree in Pharmacology, Biology, Biochemistry, Molecular Biology, Cell Biology, Translational Medicine, or a related scientific discipline preferred
Equivalent combination of education and applicable job experience may be considered
Minimum 10 years of relevant experience in the biopharmaceutical industry required; or 6 years with PhD, MD, PharmD, or equivalent
Strong knowledge of pharmacology principles in nonclinical and clinical development settings
Demonstrated commitment to keeping patients at the center of scientific evaluation and decision-making, ensuring external opportunities are assessed with a focus on potential for meaningful patient impact
Experience evaluating drug candidates, mechanisms of action, disease biology and pharmacology data to support development decisions and translational strategy
Working knowledge of regulatory requirements and expectations for nonclinical and translational support of clinical development programs
Experience leading scientific initiatives, project workstreams, diligence activities, or multidisciplinary teams
Demonstrated ability to synthesize complex data, identify key risks and opportunities, and communicate clear recommendations
Excellent verbal and written communication, presentation, collaboration, and influencing skills
Strong organizational skills with demonstrated ability to successfully manage multiple priorities, timelines, and shifting responsibilities
Scientific curiosity, intellectual rigor, and commitment to improving outcomes for patients with serious diseases
Ability to thrive in a collaborative, fast-paced, virtual biotechnology environment.

Benefits

Comp & perks

premium health
financial
work-life and well-being offerings for eligible employees and dependents
wellness and employee support programs
life insurance
disability
retirement plans with employer match
generous paid time off