Senior Upstream Process Engineer, Commercial

Thermo Fisher Scientific

Senior Upstream Process Engineer leading upstream bioprocess solutions for capital projects at Thermo Fisher Scientific. Engaging with biopharma companies to translate process requirements into technical solutions.

Posted 6/27/2026full-timeRemote • California, Massachusetts, Montana, New York, Pennsylvania • 🇺🇸 United StatesSenior💰 $120,000 - $210,000 per yearWebsite

About the role

Key responsibilities & impact

Lead upstream process design, including PFDs, P&IDs, balances, and equipment specs
Develop scalable solutions for media prep and bioreactor-based manufacturing with automation
Ensure compliance with cGMP and global regulatory standards
Lead FEL/FEED efforts, translating customer needs into defined scopes
Develop costed proposals with scope, assumptions, risks, and exclusions
Support CAPEX estimates aligned with commercial and margin goals
Serve as primary technical contact for customers and project teams
Lead design reviews, technical discussions, and executive presentations
Collaborate cross-functionally across sales, engineering, and global teams
Contribute to technical marketing (white papers, webinars, presentations)
Represent Thermo Fisher at industry events to promote bioproduction solutions
Ensure smooth handoff to execution teams with clear scope and continuity

Requirements

What you’ll need

Bachelor’s degree in Chemical Engineering, Biochemical Engineering, Mechanical Engineering, or related technical field required; Master’s or PhD preferred
8+ years of experience in process engineering or bioprocess system design within the biopharma or life sciences industry
Strong expertise in upstream bioprocessing, including cell culture, media preparation, and single-use technologies
Experience with capital equipment projects and development of complex engineering proposals
Demonstrated ability to lead front-end engineering, scope definition, and technical solution development
Familiarity with automation platforms (e.g., DeltaV, PLC/SCADA systems) and integration within bioprocess facilities preferred
Strong understanding of cGMP and global regulatory frameworks (FDA, EMA, ICH)
Proven ability to influence and collaborate across cross-functional and global teams
Excellent communication and presentation skills, with experience engaging customer stakeholders and executive audiences
Ability to manage multiple priorities in a fast-paced, customer-driven environment

Benefits

Comp & perks

Competitive remuneration
Annual incentive plan bonus scheme
Healthcare
Company 401(k)
At least 120 hours paid time off (PTO)
10 paid holidays annually
Paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave)
Accident and life insurance
Short- and long-term disability
Retirement and savings programs
Employees’ Stock Purchase Plan (ESPP)

ATS Keywords

✓ Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools

upstream process designPFDsP&IDsmedia preparationbioreactor-based manufacturingautomationcapital equipment projectsengineering proposalscell culturesingle-use technologies

Soft Skills

leadershipcollaborationcommunicationpresentation skillsinfluencescope definitiontechnical solution developmentcustomer engagementmulti-priority managementcross-functional teamwork

Certifications

Bachelor’s degreeMaster’s degreePhD