Senior Director, Program Management

Summit Therapeutics, Inc.

Senior Director leading program management initiatives for Summit Therapeutics, ensuring alignment across multiple development programs. Focus on oncology to improve patients' lives through strategic leadership and operational execution.

Posted 7/6/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $217,000 - $271,000 per yearWebsite

Tech Stack

Tools & technologies

About the role

Key responsibilities & impact

Manage multiple programs or a therapeutic portfolio to maximize pipeline
Partner with executive leadership on program, indication, and portfolio strategy, including prioritization and sequencing
Define and oversee major milestones, decision points, objectives, and inflection points across programs
Lead scenario planning, trade-off analyses, and decision frameworks to support executive decision-making
Ensure alignment across Development, Regulatory, Manufacturing, and Corporate Strategy
Lead and integrate complex cross-functional workstreams across Research, Development, Regulatory, and Manufacturing
Facilitate effective decision-making and accountability across global teams and external partners
Present clear insights, recommendations, and program status to C-suite and senior leadership
Mentor and develop Program Management leaders and strengthen organizational capability
Oversee end-to-end program execution, including activation of new indications post–Go decision
Ensure consistent application of program management standards, dashboards, and governance models
Chair timely, efficient, and action-oriented team meetings to coordinate operations and communications.
Review and validate integrated program plans, timelines, and metrics for accuracy and strategic alignment
Represent Program Management on senior governance forums and key internal or external teams
Oversee integrated, cross-program timelines aligned with enterprise goals
Partner with functional leaders on budgets and forecast planning
Lead portfolio-level scenario and contingency planning to support strategic agility
Ensure data integrity and transparency in executive reporting
Identify and manage program- and portfolio-level risks and mitigation strategies
Communicate risks, opportunities, and trade-offs clearly to executive leadership
Drive continuous improvement of program management processes, tools, and operating models
Lead strategic initiatives to mature the Program Management function as the company grows
All other duties as assigned

Requirements

What you’ll need

Bachelor’s degree and minimum 15 years of relevant project management/scientific experience within the pharmaceutical industry; OR a MS or MBA and minimal 12 years of relevant experience; OR a PhD in a scientific field or a PharmD, DVM or MD degree with 7+ years of relevant experience
12–15+ years of pharmaceutical or biotech industry experience with progressive responsibility in program or portfolio management
Extensive pharmaceutical drug development experience required;
Prior solid tumor oncology experience, including late-stage development and registrational trials, required
Demonstrated success leading complex, global, cross-functional programs and influencing senior executives
Experience managing alliances and external partners strongly preferred
Proven ability to balance strategic leadership with operational execution
Exceptional communication, facilitation, and presentation skills
Strong proficiency in program management and planning tools (e.g., MS Office, Project, Smartsheet)
Willing to travel for key meetings.

Benefits

Comp & perks

🌐 Worldwide ❌ Jobs You've Hidden ⭐️ Saved Jobs ✅ Applied Jobs ✉️ Email Alerts 👤 Account Summit Therapeutics, Inc. Website LinkedIn All Job Openings 201 - 500 employees Founded 2003 🧬 Biotechnology 💊 Pharmaceuticals 🔥 Funding within the last year 💰 $500M Post-IPO Equity - Summit Therapeutics on 2025-10 Biotechnology
Pharmaceuticals Summit Therapeutics, Inc. is a biopharmaceutical oncology company focused on the discovery, development, and commercialization of novel medicinal therapies to improve quality and duration of life for patients with serious unmet medical needs. The company is advancing ivonescimab (SMT112), a novel bispecific antibody targeting PD-1 and VEGF, through multiple Phase 3 clinical trials for non-small cell lung cancer and other solid tumors under license from Akeso. Summit emphasizes clinical development, regulatory filing strategies, and potential commercialization in its licensed territories while promoting patient- and caregiver-friendly treatment options. Senior Director, Program Management 🔥 8 minutes ago 🇺🇸 United States – Remote 💵 $217k - $271k / year ⏰ Full Time 🟠 Senior 📋 Program Manager Apply Now Find Hiring Managers Customize resume + cover letter Report problem ☆ Save ☑️ Mark as applied ❌ Hide 📋 Description
Manage multiple programs or a therapeutic portfolio to maximize pipeline
Partner with executive leadership on program, indication, and portfolio strategy, including prioritization and sequencing
Define and oversee major milestones, decision points, objectives, and inflection points across programs
Lead scenario planning, trade-off analyses, and decision frameworks to support executive decision-making
Ensure alignment across Development, Regulatory, Manufacturing, and Corporate Strategy
Lead and integrate complex cross-functional workstreams across Research, Development, Regulatory, and Manufacturing
Facilitate effective decision-making and accountability across global teams and external partners
Present clear insights, recommendations, and program status to C-suite and senior leadership
Mentor and develop Program Management leaders and strengthen organizational capability
Oversee end-to-end program execution, including activation of new indications post–Go decision
Ensure consistent application of program management standards, dashboards, and governance models
Chair timely, efficient, and action-oriented team meetings to coordinate operations and communications.
Review and validate integrated program plans, timelines, and metrics for accuracy and strategic alignment
Represent Program Management on senior governance forums and key internal or external teams
Oversee integrated, cross-program timelines aligned with enterprise goals
Partner with functional leaders on budgets and forecast planning
Lead portfolio-level scenario and contingency planning to support strategic agility
Ensure data integrity and transparency in executive reporting
Identify and manage program- and portfolio-level risks and mitigation strategies
Communicate risks, opportunities, and trade-offs clearly to executive leadership
Drive continuous improvement of program management processes, tools, and operating models
Lead strategic initiatives to mature the Program Management function as the company grows
All other duties as assigned 🎯 Requirements
Bachelor’s degree and minimum 15 years of relevant project management/scientific experience within the pharmaceutical industry; OR a MS or MBA and minimal 12 years of relevant experience; OR a PhD in a scientific field or a PharmD, DVM or MD degree with 7+ years of relevant experience
12–15+ years of pharmaceutical or biotech industry experience with progressive responsibility in program or portfolio management
Extensive pharmaceutical drug development experience required;
Prior solid tumor oncology experience, including late-stage development and registrational trials, required
Demonstrated success leading complex, global, cross-functional programs and influencing senior executives
Experience managing alliances and external partners strongly preferred
Proven ability to balance strategic leadership with operational execution
Exceptional communication, facilitation, and presentation skills
Strong proficiency in program management and planning tools (e.g., MS Office, Project, Smartsheet)
Willing to travel for key meetings. Apply Now 📊 Check your resume score for this job Improve your chances of getting an interview by checking your resume score before you apply. Check Resume Score Similar Jobs Senior Program Manager – Federal Programs 🔥 1 hour ago Essnova Solutions, Inc. 11 - 50 🏛️ Government 🔒 Cybersecurity 🤖 Artificial Intelligence Website LinkedIn All Job Openings Senior Program Manager leading federal IT programs and managing contracts for Essnova Solutions. Delivering technical solutions across government sectors with a focus on operational excellence. 🇺🇸 United States – Remote ⏰ Full Time 🟠 Senior 📋 Program Manager Program Manager 🔥 1 hour ago Natera 1001 - 5000 🧬 Biotechnology ⚕️ Healthcare Insurance 💊 Pharmaceuticals Website LinkedIn All Job Openings Program Manager leading product development initiatives at Natera, driving execution across cross-functional teams. Responsibilities include regulatory alignment and project management to ensure timely delivery of milestones. 🇺🇸 United States – Remote ⏰ Full Time 🟡 Mid-level 🟠 Senior 📋 Program Manager 🦅 H1B Visa Sponsor Senior Partner Program Manager – Strategic Initiatives 🔥 4 hours ago Datadog 1001 - 5000 🔒 Cybersecurity ☁️ SaaS 🏢 Enterprise Website LinkedIn All Job Openings Senior Partner Program Manager designing and scaling strategic initiatives for Datadog's Channels & Alliances. Collaborating with cross-functional stakeholders to drive partner-driven growth. 🇺🇸 United States – Remote 💵 $163k - $204k / year ⏰ Full Time 🟠 Senior 📋 Program Manager 🦅 H1B Visa Sponsor Chemical Warfare Material Program Manager 🔥 15 hours ago AECOM 10,000+ employees Website LinkedIn All Job Openings Chemical Warfare Material Program Manager managing remediation services to Federal market clients. Collaborating with technical experts to ensure project delivery and compliance. 🇺🇸 United States – Remote 💵 $150k - $200k / year ⏰ Full Time 🟠 Senior 🔴 Lead 📋 Program Manager 🦅 H1B Visa Sponsor Strategic Program Manager 🔥 19 hours ago Fictiv 201 - 500 Website LinkedIn All Job Openings Strategic Program Manager partnering with enterprises to accelerate product launches at MISUMI Americas. Leading cross-functional teams to deliver high-quality standards within complex programs. 🇺🇸 United States – Remote 💵 $105k - $150k / year 💰 $100M Series E on 2022-05 ⏰ Full Time 🟡 Mid-level 🟠 Senior 📋 Program Manager 🦅 H1B Visa Sponsor View More Program Manager Jobs 🌐 Worldwide Built by Lior Neu-ner. I'd love to hear your feedback — Get in touch via DM or support@remoterocketship.com Search Search Jobs by country Search jobs by city Search jobs by job title Search entry-level jobs Search junior-level jobs Search senior-level jobs Search jobs by tech stack Search jobs by contract type Search remote internships Search remote part-time jobs Remote jobs Anywhere in the World Companies Hiring Anywhere in the World Companies Hiring Sales People Anywhere in the World Companies Hiring Software Engineers Anywhere in the World Resources Advice Tips for finding remote jobs Interview questions and answers Resume examples Cover letter examples Post a job Affiliates Privacy policy Terms of service Job board SEO course AI Apply Copilot OpenClaw job finder Find jobs using your resume Jobs by Country Remote jobs anywhere in the world (Worldwide remote jobs) Remote jobs United States Remote jobs Australia Remote jobs Brazil Remote jobs Canada Remote jobs France Remote jobs Ireland Remote jobs Germany Remote jobs Netherlands Remote jobs Spain Remote jobs UK Popular Jobs Remote data analyst jobs Remote customer support jobs Remote executive assistant jobs Remote marketing jobs Remote product designer jobs Remote product manager jobs Remote project manager jobs Remote recruiter jobs Remote sales jobs Remote software engineer jobs Jobs by Type Remote full-time jobs Remote part-time jobs Remote contract jobs Remote internship jobs Remote entry-level jobs Remote jobs with no experience required Remote junior jobs (1-3 years of experience) Digital nomad jobs Remote jobs with no degree required Freelance remote jobs Temporary remote jobs Remote jobs hiring now Stay at home mom jobs

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Hard Skills & Tools

Project ManagementPortfolio ManagementRisk ManagementScenario PlanningDecision FrameworksMilestone DefinitionData IntegrityProgram ExecutionBudget PlanningRegulatory Compliance

Soft Skills

FacilitationMentoringAccountabilityInfluencingContinuous Improvement