Senior Director, Biostatistics

Sabin Vaccine Institute

Senior Director of Biostatistics leading statistical activities supporting late-stage vaccine development programs. Ensuring statistical rigor and providing strategic input for Phase 2/3 clinical trials through team collaboration.

Posted 5/22/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $200,000 - $240,000 per yearWebsite

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Provide strategic leadership for statistical activities supporting late-stage vaccine development programs
Ensure statistical rigor across clinical development, translational sciences, and CMC
Provide strategic input to senior leadership on statistical implications of development strategies
Lead statistical strategy for Phase 2/3 clinical trials
Oversee statistical deliverables from CROs and external partners
Partner with clinical and translational teams to support immunobridging models
Guide statistical design and analysis of pivotal nonclinical studies
Manage relationships with external vendors, key opinion leaders, and regulatory agencies
Mentor and develop internal statisticians and other team members

Requirements

What you’ll need

Minimum of a graduate degree in Biostatistics, Statistics, or related field; doctoral degree strongly preferred
14+ years of biostatistics experience in pharma/biotech, with substantial leadership in late-phase clinical development
Expertise in clinical trial design, regulatory submissions, and statistical modeling in vaccines or infectious diseases.
Experience with immunobridging, logistical regression methods, and Bayesian or frequentist modeling
Working knowledge of CMC statistics, assay validation, and nonclinical study design.
Proficiency in statistical programming (e.g., SAS, R, Python); experience with CDISC standards is a plus
Proven leadership, communication, and cross-functional collaboration skills

Benefits

Comp & perks

medical, dental, and vision coverage
flexible spending accounts
flexible vacation and sick leave
employer-paid life and disability insurance
11 federal holidays
end-of-year winter break
employer-matching 401(k) plan

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

biostatisticsclinical trial designregulatory submissionsstatistical modelingimmunobridginglogistical regressionBayesian modelingfrequentist modelingCMC statisticsassay validation

Soft Skills

leadershipcommunicationcross-functional collaborationmentoring

Certifications

graduate degree in Biostatisticsgraduate degree in Statisticsdoctoral degree in related field