Principal Scientist, Pathology

Roche

Principal Scientist in Pathology providing scientific leadership and expertise in drug development at Genentech. Collaborating with teams to implement safety assessment programs and regulatory studies.

Posted 6/10/2026full-timeSouth San Francisco • California • 🇺🇸 United StatesLead💰 $181,200 - $336,400 per yearWebsite

About the role

Key responsibilities & impact

Provide veterinary clinical, technical, and scientific expertise on in-house and CRO-based studies from protocol development through necropsy, clinical pathology, and histopathology evaluations.
Collaborate closely with toxicologists and study operations professionals.
Work independently to leverage literature to develop and optimize best-evidence arguments in support of data interpretation or experimental approaches.
Lead or coauthor high quality scientific manuscripts and regulatory documents.
Collaborate with in vitro systems scientists to characterize and qualify assays for assessment of toxicity.
Design and conduct in vitro and/or in vivo investigative and mechanistic studies in collaboration with toxicologists and subject matter experts.
Advance applications of digital pathology for greater scientific insights and workflow efficiencies.
Participate in the therapeutic area focused Expert Working Groups.
Participate in and lead interdisciplinary project teams.

Requirements

What you’ll need

A DVM/VMD, or equivalent, and board certification in the American College of Veterinary Pathology or European College of Veterinary Pathology.
PhD in Integrative Pathobiology, or related discipline, preferred.
Alternatively, a minimum of 5 years of relevant industry experience.

Benefits

Comp & perks

Relocation Assistance benefits are not available for this posting.
A discretionary annual bonus may be available based on individual and Company performance.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical pathologyhistopathologytoxicologyin vitro studiesin vivo studiesdata interpretationscientific manuscript writingregulatory document preparationassay characterizationmechanistic studies

Soft Skills

collaborationindependent workleadershipcommunicationinterdisciplinary teamwork

Certifications

DVMVMDboard certification in American College of Veterinary Pathologyboard certification in European College of Veterinary Pathology