Psivant Therapeutics

Research Scientist

• Design small molecule (and related modality) therapeutics using structural, simulation, ML and assay data aligned to project requirements and timelines
• Lead computational analysis and design activities on cross-functional projects from target selection and druggability analysis to clinical candidate nomination
• Integrate computational tools and medicinal chemistry knowledge for hit identification, hit-to-lead and lead optimization
• Utilize advanced computational strategies across all stages of drug discovery, including hit identification, hit-to-lead and lead optimization
• Analyze simulation and AI/ML results, derive actionable hypotheses, and effectively communicate findings to project teams
• Report to the Senior Director of CADD and collaborate closely with experimental medicinal chemistry, structural biology, and application engineering teams
• Collaborate with the computational development team to align priorities between platform application development and R&D projects
• Develop modifications and drive improvements in internal applications, building on internal physics-based simulation capabilities and assessing fidelity and accuracy of calculations
• Train and mentor team members across the organization on modeling and AI/ML concepts and applications to project needs

Principal Scientist, Computer-Aided Drug Design, CADD