VP, Global In Vitro – Scientific Operations

Proofpoint

VP of Global In Vitro Scientific Operations at Crown Bioscience overseeing oncology and immunology drug discovery programs. Leading global scientific operations to ensure quality and operational excellence in drug development.

Posted 5/28/2026full-timeRemote • Florida, Maryland, New Jersey, North Carolina, Pennsylvania • 🇺🇸 United StatesLeadWebsite

About the role

Key responsibilities & impact

Lead all global in vitro scientific operations across Crown’s sites.
Ensure consistent and high-quality execution of in vitro studies, maintaining strong scientific rigor, reproducibility, and translational relevance.
Drive operational efficiencies through standardized workflows, SOP harmonization, and continuous improvement initiatives.
Oversee end-to-end operational workflows, including study design support, resource planning, execution, QC, reporting, and on-time delivery.
Drive improvements in productivity, reproducibility, cycle time, and cross-site alignment.
Establish and track operational KPIs (quality, timeliness, resource utilization, client satisfaction).
Identify opportunities to expand and modernize in vitro capabilities.
Lead implementation of new technologies, automation, and translational assays supporting MoA, PK/PD linkage, and IND-enabling studies.
Partner with biomarker, in vivo, and translational science leaders to ensure integration across platforms.
Act as a senior scientific representative for key client meetings, supporting proposal development, study design, troubleshooting, and data interpretation.
Support BD strategy with strong scientific storytelling, customer retention insights, and expansion of strategic partnerships.
Guide teams in translating client program objectives into actionable in vitro study plans.
Ensure alignment between scientific operations, project management, quality, and commercial teams.
Support cross-site initiatives, including platform harmonization and global capability mapping.
Build a high-performance culture emphasizing scientific rigor, innovation, accountability, and client-centricity.
Provide strategic mentorship, succession planning, and competency development across assay platforms.
Oversee global in vitro budgets, headcount planning, capital equipment strategy, and site capacity allocations.
Support revenue planning, operational forecasting, and margin optimization.
Partner with finance and senior leadership to drive operational efficiency and scalability.

Requirements

What you’ll need

Ph.D. in cancer biology, immunology, pharmacology, molecular/cell biology, or related discipline.
10+ years of experience in oncology/immunology preclinical research with deep expertise in in vitro assay platforms.
7+ years of leadership experience managing scientific teams, ideally across multiple global sites.
Demonstrated track record in CRO scientific operations, with strong understanding of client expectations and data delivery requirements.
Extensive experience designing, executing, and interpreting mechanistic in vitro assays, immune effector studies, co-culture systems, and imaging-based platforms.
Proven ability to manage operational workflows, introduce new capabilities, and ensure high-quality scientific output.
Excellent communication skills, with experience in client-facing scientific roles.

Benefits

Comp & perks

Health insurance
401(k) matching
Flexible work arrangements
Professional development opportunities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

in vitro studiesmechanistic in vitro assaysimmune effector studiesco-culture systemsimaging-based platformsoperational workflowsSOP harmonizationKPI trackingresource planningdata interpretation

Soft Skills

leadershipcommunicationstrategic mentorshipclient-centricityinnovationaccountabilityteam managementscientific storytellingtroubleshootingcross-site alignment

Certifications

Ph.D. in cancer biologyPh.D. in immunologyPh.D. in pharmacologyPh.D. in molecular biologyPh.D. in cell biology