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Pfizer

Principal Software Engineer

Pfizer

Principal Software Engineer shaping Pfizer’s AI-enabled digital transformation and enterprise technology strategy. Architecting full-stack, cloud, data, ML, and LLM solutions to accelerate drug discovery and improve patient outcomes.

Posted 8/17/2026full-timeThessaloniki • 🇬🇷 GreeceLeadWebsite

Core Competencies

Role fit
Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in full-stack development, AI integration, and data architecture while driving technical strategy and fostering high-performing teams. Capable of transforming complex challenges into actionable solutions through effective stakeholder management and communication.

Highest-signal resume keywords
Full-Stack DevelopmentAI Evaluation and VerificationData Integration ArchitectureTechnical LeadershipCloud-Native Solutions

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Software DesignCode QualityArchitecture and DesignData ModelingCI/CD PipelinesMachine Learning StrategyTechnical WritingService ManagementSite Reliability EngineeringRapid Prototyping
Soft Skills
Team CollaborationStakeholder ManagementProblem DiscoveryCuriosityPrecise Communication
Tools & Technologies
Cloud PlatformsAI ToolsInfrastructure as CodeMonitoring ToolsDevOps Practices
Certifications & Qualifications
Bachelor's Degree in Computer ScienceEngineering or Related Field
Industry Keywords
Technical StrategyEngineering Delivery PracticesDeployment Best PracticesKnowledge ManagementPolymathic Engineering

Tech Stack

Tools & technologies
Cloud

About the role

Key responsibilities & impact
  • Design, build, and maintain software systems that deliver business value
  • Focus on code quality, architecture decisions, and reliable delivery
  • Leverage AI tools to enhance productivity and verify AI-generated code against quality standards
  • Bridge product development and business problem-solving through rapid solution delivery and domain expertise
  • Identify recurring patterns and lead validated solution generalization into enterprise capabilities
  • Define organization-wide technical strategy and architectural direction
  • Drive delivery of critical technical initiatives and establish engineering delivery practices
  • Shape deployment strategy, platform adoption, and deployment best practices
  • Define data integration patterns, architect large-scale data flows, and solve complex integration challenges
  • Deliver production full-stack solutions rapidly and shape full-stack engineering practices
  • Transform ambiguous situations into clear opportunities through problem discovery
  • Establish prototype-to-production practices, handoff standards, and quality gates
  • Shape AI engineering strategy, AI observability, evaluation, literacy, augmented development, and LLM integration
  • Shape developer experience, knowledge management, pattern generalization, and technical writing strategy
  • Define machine learning strategy and lead model development, fine-tuning, and retrieval augmentation initiatives
  • Shape technology-driven business strategy and represent the technical perspective at executive level
  • Manage executive stakeholder relationships and represent engineering at the highest levels
  • Develop technical leaders, shape engineering talent strategy, build high-performing teams, and mentor others
  • Shape organizational practices around curiosity, outcome ownership, polymathic engineering, precise communication, and systems thinking

Requirements

What you’ll need
  • Bachelor's degree in Computer Science, Engineering, or related field with extensive relevant experience
  • Deep technical expertise
  • Proven track record of organization-wide technical leadership
  • Expert-level business immersion, data integration, full-stack development, multi-audience communication, problem discovery, rapid prototyping and validation, stakeholder management, and team collaboration
  • Practitioner-level AI evaluation and verification, AI literacy, AI-augmented development, architecture and design, code quality and review, developer experience, knowledge management, pattern generalization, service management, site reliability engineering, and technical writing
  • Working-level cloud platforms, data modeling, DevOps and CI/CD, lean thinking and flow, technical debt management, and time management/deep work
  • Ability to work comfortably in any programming language and rapidly acquire new skills
  • Ability to architect large-scale data flows and complex multi-component systems
  • Ability to design cloud-native solutions, infrastructure as code, CI/CD pipelines, monitoring, and deployment strategies
  • Ability to establish AI governance, evaluation standards, human-in-the-loop workflows, and verification processes
  • Ability to define reliability, documentation, developer experience, and knowledge management standards across teams

Benefits

Comp & perks
  • Flexible workplace culture
  • Work-life harmony
  • Reasonable adjustments for disability inclusion
  • Opportunity to grow and develop a career
  • Ownership culture
  • Diverse and inclusive workforce
  • Opportunity to impact the health and lives of millions of people