Global Development Lead, Internal Medicine – MD, Sr. Director

Pfizer

Pfizer clinical leader guiding global development of Internal Medicine and obesity therapies. Leading cross-functional trials, regulatory submissions, and development strategy for late-stage assets.

Posted 8/13/2026full-timeNew York City • California, Illinois, New York, Washington • 🇺🇸 United StatesSenior💰 $274,500 - $457,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive knowledge in Clinical Development, Regulatory Submissions, and Project Management, with a strong focus on Cardiometabolic late-stage development and Internal Medicine. Proven ability to lead cross-functional teams, develop clinical strategies, and ensure compliance with regulatory standards.

Highest-signal resume keywords

MD Or DOCardiometabolic Late-Stage Development ExperienceClinical Development ExpertiseProject Management CapabilitiesEffective Communication Skills

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical DevelopmentRegulatory SubmissionsStudy DesignAdverse Event ManagementStatistical Analysis PlansProtocol DesignClinical Trial Data InterpretationMedical Monitoring SupportPediatric Investigation PlansGlobal Regulation Knowledge

Soft Skills

Team LeadershipConflict ManagementMentoringCoachingChange Agility

Industry Keywords

Internal MedicineEndocrinologyICH/GCPBiopharmaceutical DevelopmentClinical PharmacologyPatient EngagementRegulatory StandardsCross-Functional CollaborationStakeholder EngagementClinical Research

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Represent Clinical on the Global Medicine Team and serve as the single clinical point of accountability for assigned Internal Medicine assets
Lead cross-functional Clinical Development Teams across clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations
Design, execute, and interpret studies supporting worldwide regulatory submissions
Create and gain endorsement for Clinical Development Plans and associated protocol design documents
Partner with Medicine Team Leads to negotiate tradeoffs and milestones and deliver programs within agreed timelines and budget
Develop global clinical development plans to secure approval and reimbursement, including in China and Japan
Create pediatric investigation/study plans and associated protocol design documents
Provide input for target product profiles and regulatory activities, including product labels, core data sheets, Investigator Brochures, DSURs, and PBRERs
Develop clinical development enabling strategies, including digital/innovation and patient engagement approaches
Partner with trial clinicians on governance reviews and provide clinical development strategy input
Provide therapy-area and indication expertise for clinical data review, CRF design, signal interpretation, and adverse-event contextualization
Provide specialized medical monitoring support when required
Partner with statistics and programming on statistical analysis plans, TLFs, and database release
Develop submission-level deliverables, including IAP, IARP, submission TLFs, SCE, and SCS
Support interpretation and communication of clinical trial data
Review and approve submission-level safety narrative plans
Support product label development and maintenance
Engage external stakeholders, including advisory boards, steering committees, DMCs, adjudication committees, patients, and patient advocates
Provide regulatory submission, disclosure, and product-defense support
Ensure compliance with internal SOPs and external regulatory standards
Review IIR proposals
Potentially assume clinical leadership responsibilities for other late-stage assets in Pfizer’s Obesity portfolio

Requirements

What you’ll need

MD or DO
Endocrinologist or internal medicine physician
Cardiometabolic late-stage development experience, including type 2 diabetes experience
8+ years of relevant experience
Track record of success in academia and/or biopharmaceutical clinical research and development
Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, and adverse event management
Demonstrated clinical/medical, administrative, and project management capabilities
Effective verbal and written communication skills with individuals inside and outside Pfizer
Demonstrated experience managing and training large teams in clinical development
Demonstrated experience in designing and launching large teams preferred
Medical/scientific credibility and excellence in pharmaceutical development
Ability to coordinate and execute clinical development or lifecycle strategy
Understanding of complexities and recent developments in principal disease areas
Ability to discuss scientific/mechanistic aspects of drug development and commercial and regulatory issues
Ability to work in a highly complex matrixed environment and influence cross-functional teams
Persuasive and effective staff leadership
Ability to manage and motivate internal clinical-trial teams
Conflict-management, mentoring, and coaching capabilities
Team-building and accountability capabilities
Change agility and ability to deliver amid organizational change
Breadth of diverse leadership experiences, including influencing and collaborating with peers, developing and coaching others, and overseeing colleagues’ work
Must be authorized to be employed in the U.S. by any employer
Must have permanent work authorization in the United States
U.S. work visa sponsorship is not available now or in the future
Up to 30% travel may be required

Benefits

Comp & perks

Relocation support available
Up to 30% travel may be required
Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary
Eligibility to participate in Pfizer’s share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Paid holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation assistance may be available based on business needs and/or eligibility