Global Development Lead, Internal Medicine – MD

Pfizer

Global Development Lead advancing Pfizer’s Internal Medicine therapies through late-stage clinical development. Leading cross-functional studies, regulatory submissions, and clinical strategy for cardiometabolic assets.

Posted 8/13/2026full-timeNew York City • California, Illinois, New York, Washington • 🇺🇸 United StatesSenior💰 $274,500 - $457,500 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates extensive knowledge in Clinical Development, Regulatory Submissions, and Project Management, with a strong focus on Cardiometabolic late-stage development and Internal Medicine. Proven ability to lead cross-functional teams, develop comprehensive clinical strategies, and ensure compliance with regulatory standards.

Highest-signal resume keywords

MD Or DOCardiometabolic Late-Stage Development ExperienceClinical Development KnowledgeProject Management CapabilitiesLeadership Experience

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Applicant Tracking System Keywords

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Hard Skills

Clinical Development PlansRegulatory SubmissionsAdverse Event ManagementStatistical Analysis PlansClinical Trial Data InterpretationProtocol DesignMedical MonitoringDigital/Innovation StrategiesPediatric Investigation PlansIAP And IARP Development

Soft Skills

Effective Communication SkillsTeam-Building CapabilitiesConflict ManagementMentoring And CoachingAbility To Influence Cross-Functional Teams

Industry Keywords

ICH/GCPBiopharmaceutical IndustryInternal MedicineType 2 DiabetesClinical ResearchGlobal RegulationPatient EngagementRegulatory StandardsClinical PharmacologySafety Narrative Plans

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Represent Clinical on the Global Medicine Team and serve as the single clinical point of accountability for clinical development of assigned Internal Medicine assets
Lead cross-functional Clinical Development Teams across clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations
Design, execute, and interpret studies supporting worldwide regulatory submissions
Create and gain endorsement for Clinical Development Plans and protocol design documents
Partner with Medicine Team Leads to negotiate tradeoffs and milestones and deliver clinical programs within agreed timelines and budgets
Develop comprehensive global clinical development plans, including pediatric investigation/study plans
Provide input for target product profiles and regulatory activities, labels, core data sheets, Investigator Brochures, DSURs, and PBRERs
Develop clinical development enabling strategies, including digital/innovation and patient engagement approaches
Partner with trial clinicians on governance reviews and provide therapeutic-area clinical development strategy input
Provide clinical review of data, including CRF design, adverse-event contextualization, and signal interpretation
Provide specialized medical monitoring support when required
Partner with statistics and programming on statistical analysis plans, TLFs, and database release
Develop submission-level deliverables, including IAP, IARP, submission TLFs, SCE, and SCS
Support interpretation and communication of clinical trial data
Review and approve submission-level safety narrative plans
Support product label development and maintenance
Engage external stakeholders, including advisory boards, steering committees, DMCs, adjudication committees, patients, and patient advocates
Provide regulatory submission, disclosure, and product-defense support
Ensure compliance with internal SOPs and external regulatory standards
Review IIR proposals
May provide specialized monitoring support and lead clinical leadership activities for other late-stage assets in the Obesity portfolio

Requirements

What you’ll need

MD or DO
Endocrinologist or internal medicine physician
Cardiometabolic late-stage development experience, including type 2 diabetes experience
8+ years of relevant experience
Track record of success in academia and/or the biopharmaceutical industry in clinical research and development
Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, and adverse event management
Demonstrated clinical/medical, administrative, and project management capabilities
Effective verbal and written communication skills
Demonstrated experience managing and training large teams in clinical development
Medical/scientific credibility and excellence in pharmaceutical development
Ability to coordinate and execute clinical development or lifecycle strategy
Understanding of complexities and recent developments in principal disease areas
Ability to discuss scientific/mechanistic, commercial, and regulatory aspects of drug development
Management experience in a highly complex matrixed environment
Ability to influence cross-functional teams
Leadership experience as a persuasive and effective leader of staff
Ability to manage and motivate internal clinical-trial teams
Conflict-management, mentoring, and coaching capabilities
Team-building capabilities
Accountability for results and delivery
Ability to remain effective amid organizational change
Ability to influence and collaborate with peers, develop and coach others, and oversee colleagues’ work
Candidates must be authorized to be employed in the U.S. by any employer
This position requires permanent work authorization in the United States
U.S. work visa sponsorship is not available now or in the future
Up to 30% travel may be required
Must live within commuting distance of the assigned work location and work on-site an average of 2.5 days per week

Benefits

Comp & perks

Annual base salary range of $274,500.00 to $457,500.00
Eligible for Pfizer’s Global Performance Plan with a bonus target of 25.0% of base salary
Eligibility to participate in Pfizer’s share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Paid holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation support available
Relocation assistance may be available based on business needs and/or eligibility