Global Development Lead, Internal Medicine – Sr. Director

Pfizer

Global Development Lead guiding Pfizer’s Internal Medicine clinical programs and cross-functional teams. Driving late-stage drug development, regulatory submissions, and worldwide approval strategies.

Posted 8/13/2026full-timeNew York City • California, Illinois, New York, Washington • 🇺🇸 United StatesSenior💰 $214,900 - $358,100 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates extensive knowledge in clinical development and regulatory compliance, with a strong track record in leading cross-functional teams and managing complex clinical programs. Proficient in designing clinical development plans and executing studies for global regulatory submissions.

Highest-signal resume keywords

Clinical Development LeadershipRegulatory Submission ExpertiseProject Management SkillsCross-Functional Team CollaborationAdverse-Event Management

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical DevelopmentRegulatory ComplianceStudy DesignData InterpretationStatistical AnalysisProtocol DesignClinical Trial ManagementIAP DevelopmentICH/GCP KnowledgePediatric Investigation Plans

Soft Skills

Effective CommunicationTeam LeadershipConflict ManagementMentoringStakeholder Engagement

Industry Keywords

Cardiometabolic DevelopmentType 2 DiabetesBiopharmaceutical ResearchClinical PharmacologyPatient EngagementGlobal RegulationAdvisory BoardsSteering CommitteesDMCsAdverse-Event Contextualization

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Represent Clinical on the Global Medicine Team and serve as the single clinical point of accountability for assigned Internal Medicine assets
Lead cross-functional Clinical Development Teams across clinical, clinical pharmacology, statistics, safety, commercial, patient access, and operations
Design, execute, and interpret studies supporting worldwide regulatory submissions
Create and secure endorsement for Clinical Development Plans and associated protocol design documents
Partner with Product Team Leads to negotiate tradeoffs, milestones, timelines, and budgets
Develop comprehensive clinical development plans supporting global approval and reimbursement, including China and Japan
Create pediatric investigation/study plans and protocol design documents
Develop clinical development enabling strategies involving digital innovation and patient engagement
Partner with trial clinicians on governance reviews and provide therapeutic-area strategy input
Provide clinical review of data, including CRF design, signal interpretation, and adverse-event contextualization
Provide specialized medical monitoring support when required
Partner on statistical analysis plans, table listings, figures, and database release
Develop submission-level deliverables, including IAP, IARP, submission TLFs, SCE, and SCS
Support interpretation and communication of clinical trial data
Review and approve submission-level safety narrative plans
Support product label development and maintenance
Engage external stakeholders including advisory boards, steering committees, DMCs, adjudication committees, patients, and patient advocates
Provide regulatory submission, disclosure, and product-defense support
Ensure compliance with internal SOPs and external regulatory standards
Review IIR proposals
May provide specialized monitoring support and assume additional clinical leadership responsibilities for the Obesity portfolio

Requirements

What you’ll need

BS with 12 years of relevant clinical/industry experience, or PhD with 7 years of relevant clinical/industry experience
Experience leading cardiometabolic late-stage development programs, including type 2 diabetes
Relevant experience and track record of success in academic and/or biopharmaceutical clinical research and development
Extensive knowledge of clinical development, global and regional regulation, ICH/GCP, and adverse-event management
Demonstrated clinical/medical, administrative, and project-management capabilities
Effective verbal and written communication skills with internal and external stakeholders
Demonstrated experience managing and training large teams in clinical development
Demonstrated experience in designing and launching large teams preferred
Medical/scientific credibility and track record in pharmaceutical development
Understanding of complexities and recent developments in principal disease areas
Ability to discuss scientific, mechanistic, commercial, and regulatory aspects of drug development
Ability to work in a highly complex matrixed environment and influence cross-functional teams
Ability to lead, mentor, coach, motivate, and manage internal clinical-trial teams
Ability to manage conflict, build teams, drive accountability, and adapt to organizational change
Up to 30% travel may be required
Must be authorized to be employed in the U.S. by any employer
Permanent work authorization in the United States required
U.S. work visa sponsorship is not available now or in the future

Benefits

Comp & perks

Annual base salary ranging from $214,900.00 to $358,100.00
Eligible for Pfizer’s Global Performance Plan with a bonus target of 22.5% of base salary
Eligibility to participate in Pfizer’s share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Paid holiday and personal days
Paid caregiver/parental and medical leave
Medical, prescription drug, dental and vision coverage
Relocation support available
Relocation assistance may be available based on business needs and/or eligibility