Senior Director, Portfolio and Technology Strategy

Pfizer

Senior Director providing strategic leadership in bioprocess R&D’s non-GMP pilot plants and technology strategy. Overseeing project management and development for biopharmaceuticals and biologics.

Posted 5/29/2026full-timeAndover • Massachusetts, Montana, Washington • 🇺🇸 United StatesSenior💰 $230,900 - $384,800 per yearWebsite

About the role

Key responsibilities & impact

Lead portfolio operations across BRD ensuring alignment of development priorities, pilot capacity, resources, timelines, and execution risk across programs.
Design and implement metric driven portfolio tracking systems to allow rapid and flexible adjustments to resource allocations according to project prioritizations.
Collaborate with BRD clinical MFG and the BRD LT in the scheduling and prioritization of projects in the non-GMP and GMP pilot plants to deliver the portfolio.
Serve as the primary contact to BTxPS Portfolio group, ensuring that information on new projects and technologies and changes to on-going projects is transferred into BRD in a timely manner.
Work with ARD and PhRD portfolio groups to coordinate project initiations at PICM/PPMT and overall project progression through periodic touchpoints.
Provide a mature and experienced perspective on portfolio tracking, project issues, and prioritization to ensure robust oversight and communication of project milestones, deliverables and issues.
Provide strategic and technical leadership for non‑GMP pilot plants, enabling effective scale‑up, process characterization, and delivery of drug substance for pre‑clinical and clinical studies.
Oversees pilot plant readiness, including equipment strategy, maintenance and turnaround, media and buffer support, and inventory management across sites.

Requirements

What you’ll need

B.S. or M.S. in Chemical Engineering, Biochemical Engineering, Biology, or related field with a minimum of 12+ years of relevant experience in biopharmaceutical development or manufacturing, or Ph.D. with a minimum of 7+ years of experience.
Proven experience leading and managing direct reports
Extensive experience/knowledge in process development, pilot‑scale operations, and portfolio enablement for biologics and advanced therapeutic modalities.
Demonstrated leadership of complex, multi‑disciplinary, multi‑site organizations in a matrixed environment.
Deep understanding of GLP/GMP principles, regulatory guidance, and CMC development expectations.
Proven ability to make strategic decisions balancing technical rigor, portfolio priorities, and execution speed.

Benefits

Comp & perks

401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

portfolio tracking systemsprocess developmentpilot-scale operationsproject managementresource allocationscale-upprocess characterizationdrug substance deliveryinventory managementequipment strategy

Soft Skills

leadershipcommunicationstrategic decision-makingcollaborationoversightproblem-solvingprioritizationorganizational skillsinterpersonal skillsflexibility

Certifications

B.S. in Chemical EngineeringM.S. in Chemical EngineeringPh.D. in Chemical EngineeringB.S. in Biochemical EngineeringM.S. in Biochemical EngineeringPh.D. in Biochemical EngineeringB.S. in BiologyM.S. in BiologyPh.D. in Biology