Senior Director, Global Commercial Strategy Transformation Lead

Pfizer

. The Global Commercial Strategy Transformation Lead is responsible for designing, governing, and continuously evolving the AI operating system that underpins how Global Commercial Strategy (GCS) works .

Posted 5/21/2026full-timeNew York City • Illinois, New York, Pennsylvania • 🇺🇸 United StatesSenior💰 $214,900 - $358,100 per yearWebsite

About the role

Key responsibilities & impact

The Global Commercial Strategy Transformation Lead is responsible for designing, governing, and continuously evolving the AI operating system that underpins how Global Commercial Strategy (GCS) works
Reporting to the Head of GCS, this leader owns the transformation architecture — the roadmap, standards, and operating model that ensure GCS compounds its AI investment into organizational intelligence
Lead the systems-thinking architecture across the three core parts of GCS
Continuously evaluate the external environment — new technology, competitor strategies, and changing customer, payer, and patient behaviors — and translate those signals into prioritized architectural improvements
Design, own, and evolve the GCS AI Blueprint and operating system in close coordination with the AI Acceleration organization
Lead the GCS AI transformation roadmap end to end, in close partnership with AI Acceleration leaders
Set, implement, and hold AI standards and policy across all three divisions
Design and deliver the GCS AI builder community capability framework and change management architecture
Operate as the GCS voice in CMO-level AI Acceleration transformation conversations

Requirements

What you’ll need

Bachelor's degree in Life Sciences, Business, Marketing, or related field required
MBA or other advanced degree (PhD, MD, PharmD) strongly preferred
Minimum 12+ years of marketing experience at Global, Regional, Local (GRL) level across in-line, launch, and LoE environments, US and ex-US
Deep subject-matter expertise across Brand Strategy, Customer Journey Design, Message Architecture, Creative Development, Omnichannel Journey Design, Tactical Execution, Measurement, Testing, and Optimization
Transformation experience, leading matrixed organizations undergoing significant change
Pharmaceutical or life sciences background required
Partner with AI Acceleration on the construction of AI agent systems, canonical reference architectures, and governed deployment frameworks in GCS settings
Large-scale transformation leadership in a complex multifunctional organization
Capability and change management at scale across geographically diverse regions and local markets
Demonstrated ability to lead cross-functional teams and influence without direct authority while managing complex stakeholder environments
Track record of building and developing high-performing teams
Systems thinking — ability to operate simultaneously at enterprise, divisional, and workflow level in a highly matrixed, rapidly changing organization

Benefits

Comp & perks

Comprehensive and generous benefits and programs to help our colleagues lead healthy lives
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

AI operating systemtransformation architectureGCS AI BlueprintBrand StrategyCustomer Journey DesignMessage ArchitectureOmnichannel Journey DesignTactical ExecutionMeasurementOptimization

Soft Skills

leadershipsystems thinkingchange managementinfluence without authoritystakeholder managementteam buildingcross-functional collaborationorganizational intelligencestrategic thinkingcommunication

Certifications

Bachelor's degreeMBAPhDMDPharmD